CY1105868T1 - Χρηση υποκατεστημενων αμινομεθυλ χρωμανων στην θepαπεια των παρενepγειων των νευροληπτικων - Google Patents
Χρηση υποκατεστημενων αμινομεθυλ χρωμανων στην θepαπεια των παρενepγειων των νευροληπτικωνInfo
- Publication number
- CY1105868T1 CY1105868T1 CY20061101826T CY061101826T CY1105868T1 CY 1105868 T1 CY1105868 T1 CY 1105868T1 CY 20061101826 T CY20061101826 T CY 20061101826T CY 061101826 T CY061101826 T CY 061101826T CY 1105868 T1 CY1105868 T1 CY 1105868T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- neuroideptic
- dyes
- substituted aminomethyl
- adverse reactions
- Prior art date
Links
- 230000002411 adverse Effects 0.000 title abstract 2
- -1 AMINOMETHYL Chemical class 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 title 1
- 208000027776 Extrapyramidal disease Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000016285 Movement disease Diseases 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 229940035678 anti-parkinson drug Drugs 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Υποκατεστημένες αμινομεθύλ χρωμάνες, ένα από τα οπτικά τους ισομερή ή φαρμακολογικώς αποδεκτά άλατα τους, που χρησιμοποιούνται για την κατασκευή μιας φαρμακευτικής ουσίας για την θεραπεία των ανεπιθύμητων ενεργειών των αντί- παρκινσονικών φαρμάκων στις εξωπυραμιδικές κινητικές διαταραχές και/ή για την κατασκευή μιας φαρμακευτικής ουσίας για την θεραπεία των εξωπυραμιδικών συμπτωμάτων (EPS) που επάγονται από τα νευροληπτικά. Μια προτιμώμενη ένωση είναι το (-)- (R) -2- {4- [[3,4- δίεδρο-2Η- βενζοπυραν-2- ύλ)- μεθύλ] άμινο] βουτύλ}-1,2- βενζοϊσοθειαζολ-3- (2Η)-όνη-1,1- διοξείδιο ή ένα φυσιολογικώς αποδεκτό άλας εξ αυτού.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01121910 | 2001-09-12 | ||
| EP02767352A EP1425008B1 (en) | 2001-09-12 | 2002-08-09 | Use of substituted aminomethyl chromans in the treatment of side effects of neuroleptics |
| PCT/EP2002/008912 WO2003022269A1 (en) | 2001-09-12 | 2002-08-09 | Novel use of substituted aminomethyl chromans for the treatment of movement disorders and of adverse effects induced by drugs administered to treat extrapyramidal movement disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1105868T1 true CY1105868T1 (el) | 2011-02-02 |
Family
ID=8178618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101826T CY1105868T1 (el) | 2001-09-12 | 2006-12-20 | Χρηση υποκατεστημενων αμινομεθυλ χρωμανων στην θepαπεια των παρενepγειων των νευροληπτικων |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20040235920A1 (el) |
| EP (1) | EP1425008B1 (el) |
| JP (1) | JP2005522410A (el) |
| KR (1) | KR100886185B1 (el) |
| CN (1) | CN1303996C (el) |
| AR (1) | AR036509A1 (el) |
| AT (1) | ATE341322T1 (el) |
| AU (1) | AU2002331220B2 (el) |
| BR (1) | BR0212199A (el) |
| CA (1) | CA2458628A1 (el) |
| CY (1) | CY1105868T1 (el) |
| DE (1) | DE60215203T2 (el) |
| DK (1) | DK1425008T3 (el) |
| ES (1) | ES2272771T3 (el) |
| HU (1) | HUP0401317A3 (el) |
| MX (1) | MXPA04002304A (el) |
| MY (1) | MY130522A (el) |
| PL (1) | PL207146B1 (el) |
| PT (1) | PT1425008E (el) |
| RU (1) | RU2320336C2 (el) |
| SI (1) | SI1425008T1 (el) |
| WO (1) | WO2003022269A1 (el) |
| ZA (1) | ZA200402774B (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7211590B2 (en) | 2002-08-01 | 2007-05-01 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
| WO2012048710A1 (en) * | 2010-10-15 | 2012-04-19 | Concit Pharma Aps | Combinations of serotonin receptor agonists for treatment of movement disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983400A (en) * | 1986-06-16 | 1991-01-08 | Merck & Co., Inc. | Controlled release combination of carbidopa/levodopa |
| SE9303274D0 (sv) | 1993-10-07 | 1993-10-07 | Astra Ab | Novel phenylethyl and phenylproplamines |
| IL125950A0 (en) * | 1997-09-05 | 1999-04-11 | Pfizer Prod Inc | Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy |
| DE19751949A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
| DE10101917A1 (de) * | 2001-01-16 | 2002-07-18 | Bayer Ag | Verwendung von Chromanen |
-
2002
- 2002-08-09 WO PCT/EP2002/008912 patent/WO2003022269A1/en active IP Right Grant
- 2002-08-09 SI SI200230456T patent/SI1425008T1/sl unknown
- 2002-08-09 AT AT02767352T patent/ATE341322T1/de active
- 2002-08-09 DK DK02767352T patent/DK1425008T3/da active
- 2002-08-09 BR BR0212199-9A patent/BR0212199A/pt not_active IP Right Cessation
- 2002-08-09 PL PL369827A patent/PL207146B1/pl not_active IP Right Cessation
- 2002-08-09 EP EP02767352A patent/EP1425008B1/en not_active Expired - Lifetime
- 2002-08-09 RU RU2004111284/15A patent/RU2320336C2/ru not_active IP Right Cessation
- 2002-08-09 KR KR1020047001613A patent/KR100886185B1/ko not_active IP Right Cessation
- 2002-08-09 ES ES02767352T patent/ES2272771T3/es not_active Expired - Lifetime
- 2002-08-09 HU HU0401317A patent/HUP0401317A3/hu unknown
- 2002-08-09 JP JP2003526398A patent/JP2005522410A/ja active Pending
- 2002-08-09 CA CA002458628A patent/CA2458628A1/en not_active Abandoned
- 2002-08-09 US US10/489,249 patent/US20040235920A1/en not_active Abandoned
- 2002-08-09 DE DE60215203T patent/DE60215203T2/de not_active Expired - Lifetime
- 2002-08-09 MX MXPA04002304A patent/MXPA04002304A/es active IP Right Grant
- 2002-08-09 PT PT02767352T patent/PT1425008E/pt unknown
- 2002-08-09 CN CNB028179285A patent/CN1303996C/zh not_active Expired - Fee Related
- 2002-08-09 AU AU2002331220A patent/AU2002331220B2/en not_active Ceased
- 2002-09-10 MY MYPI20023379A patent/MY130522A/en unknown
- 2002-09-11 AR ARP020103436A patent/AR036509A1/es not_active Application Discontinuation
-
2004
- 2004-04-08 ZA ZA200402774A patent/ZA200402774B/en unknown
-
2006
- 2006-12-20 CY CY20061101826T patent/CY1105868T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1425008B1 (en) | 2006-10-04 |
| AR036509A1 (es) | 2004-09-15 |
| HUP0401317A2 (en) | 2004-10-28 |
| SI1425008T1 (sl) | 2007-02-28 |
| RU2320336C2 (ru) | 2008-03-27 |
| ZA200402774B (en) | 2005-01-13 |
| HUP0401317A3 (en) | 2007-05-29 |
| US20040235920A1 (en) | 2004-11-25 |
| DE60215203D1 (de) | 2006-11-16 |
| WO2003022269A1 (en) | 2003-03-20 |
| CN1555259A (zh) | 2004-12-15 |
| BR0212199A (pt) | 2004-10-05 |
| JP2005522410A (ja) | 2005-07-28 |
| RU2004111284A (ru) | 2005-05-10 |
| PT1425008E (pt) | 2007-01-31 |
| KR20040043175A (ko) | 2004-05-22 |
| MXPA04002304A (es) | 2004-06-29 |
| CN1303996C (zh) | 2007-03-14 |
| ES2272771T3 (es) | 2007-05-01 |
| CA2458628A1 (en) | 2003-03-20 |
| DE60215203T2 (de) | 2007-10-18 |
| DK1425008T3 (da) | 2007-01-15 |
| MY130522A (en) | 2007-06-29 |
| AU2002331220B2 (en) | 2007-06-07 |
| PL207146B1 (pl) | 2010-11-30 |
| KR100886185B1 (ko) | 2009-02-27 |
| EP1425008A1 (en) | 2004-06-09 |
| ATE341322T1 (de) | 2006-10-15 |
| PL369827A1 (en) | 2005-05-02 |
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