BR0114485A - Amidas n-(4-ariloxipiperidin-1-ilalquil)cin micas como antagonistas de receptor de ccr33 - Google Patents
Amidas n-(4-ariloxipiperidin-1-ilalquil)cin micas como antagonistas de receptor de ccr33Info
- Publication number
- BR0114485A BR0114485A BR0114485-5A BR0114485A BR0114485A BR 0114485 A BR0114485 A BR 0114485A BR 0114485 A BR0114485 A BR 0114485A BR 0114485 A BR0114485 A BR 0114485A
- Authority
- BR
- Brazil
- Prior art keywords
- sub
- sup
- alkyl
- img
- character
- Prior art date
Links
- APEJMQOBVMLION-UHFFFAOYSA-N cinnamamide Chemical class NC(=O)C=CC1=CC=CC=C1 APEJMQOBVMLION-UHFFFAOYSA-N 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 5
- 150000002367 halogens Chemical class 0.000 abstract 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- -1 cyano, hydroxy Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0024675A GB0024675D0 (en) | 2000-10-09 | 2000-10-09 | Organic compounds |
| GB0120549A GB0120549D0 (en) | 2001-08-23 | 2001-08-23 | Organic compounds |
| PCT/EP2001/011627 WO2002030898A1 (en) | 2000-10-09 | 2001-10-08 | N-(4-aryloxypiperidin-1-ylalkyl) cinnamic amides as ccr33 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0114485A true BR0114485A (pt) | 2003-11-18 |
Family
ID=26245127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0114485-5A BR0114485A (pt) | 2000-10-09 | 2001-10-08 | Amidas n-(4-ariloxipiperidin-1-ilalquil)cin micas como antagonistas de receptor de ccr33 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7034042B2 (OSRAM) |
| EP (1) | EP1330436B1 (OSRAM) |
| JP (1) | JP4199539B2 (OSRAM) |
| CN (1) | CN1209351C (OSRAM) |
| AT (1) | ATE472533T1 (OSRAM) |
| AU (1) | AU2001295601A1 (OSRAM) |
| BR (1) | BR0114485A (OSRAM) |
| CA (1) | CA2423296C (OSRAM) |
| DE (1) | DE60142484D1 (OSRAM) |
| ES (1) | ES2348290T3 (OSRAM) |
| PT (1) | PT1330436E (OSRAM) |
| WO (1) | WO2002030898A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117387D0 (en) * | 2001-07-17 | 2001-09-05 | Novartis Ag | Organic compounds |
| US7524841B2 (en) * | 2002-04-25 | 2009-04-28 | Teijin Limited | 4,4-disubstituted piperidine derivatives having CCR3 antagonism |
| ZA200803939B (en) * | 2005-11-24 | 2009-10-28 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673684A (en) | 1984-04-04 | 1987-06-16 | Terumo Corporation | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient |
| JPH0660160B2 (ja) | 1985-12-13 | 1994-08-10 | テルモ株式会社 | アミド誘導体およびこれを含有する抗アレルギ−剤 |
| JPS63139124A (ja) | 1986-12-01 | 1988-06-10 | Terumo Corp | 腎炎治療剤 |
| JPS63179869A (ja) | 1987-01-20 | 1988-07-23 | Dainippon Pharmaceut Co Ltd | ピペリジン誘導体 |
| DE19756235A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
| EE200100502A (et) | 1999-03-26 | 2002-12-16 | Astrazeneca Ab | Ühendid |
| TWI227231B (en) * | 2000-07-12 | 2005-02-01 | Novartis Ag | 4-benzoyl-piperidine derivatives for treating conditions mediated by CCR-3 |
-
2001
- 2001-10-08 EP EP01976285A patent/EP1330436B1/en not_active Expired - Lifetime
- 2001-10-08 BR BR0114485-5A patent/BR0114485A/pt not_active IP Right Cessation
- 2001-10-08 WO PCT/EP2001/011627 patent/WO2002030898A1/en not_active Ceased
- 2001-10-08 AU AU2001295601A patent/AU2001295601A1/en not_active Abandoned
- 2001-10-08 DE DE60142484T patent/DE60142484D1/de not_active Expired - Lifetime
- 2001-10-08 AT AT01976285T patent/ATE472533T1/de active
- 2001-10-08 PT PT01976285T patent/PT1330436E/pt unknown
- 2001-10-08 JP JP2002534284A patent/JP4199539B2/ja not_active Expired - Fee Related
- 2001-10-08 US US10/398,533 patent/US7034042B2/en not_active Expired - Fee Related
- 2001-10-08 CA CA002423296A patent/CA2423296C/en not_active Expired - Fee Related
- 2001-10-08 ES ES01976285T patent/ES2348290T3/es not_active Expired - Lifetime
- 2001-10-08 CN CNB018171028A patent/CN1209351C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7034042B2 (en) | 2006-04-25 |
| AU2001295601A1 (en) | 2002-04-22 |
| EP1330436A1 (en) | 2003-07-30 |
| EP1330436B1 (en) | 2010-06-30 |
| CN1209351C (zh) | 2005-07-06 |
| CA2423296A1 (en) | 2002-04-18 |
| WO2002030898A1 (en) | 2002-04-18 |
| CA2423296C (en) | 2009-12-29 |
| PT1330436E (pt) | 2010-10-11 |
| ATE472533T1 (de) | 2010-07-15 |
| ES2348290T3 (es) | 2010-12-02 |
| DE60142484D1 (de) | 2010-08-12 |
| JP2004511467A (ja) | 2004-04-15 |
| JP4199539B2 (ja) | 2008-12-17 |
| CN1468222A (zh) | 2004-01-14 |
| US20040087621A1 (en) | 2004-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2125 DE 27/09/2011. |