ATE472533T1 - N-(4-aryloxypiperidin-1-ylalkyl)zimtsäureamide als ccr3-rezeptorantagonisten - Google Patents

N-(4-aryloxypiperidin-1-ylalkyl)zimtsäureamide als ccr3-rezeptorantagonisten

Info

Publication number
ATE472533T1
ATE472533T1 AT01976285T AT01976285T ATE472533T1 AT E472533 T1 ATE472533 T1 AT E472533T1 AT 01976285 T AT01976285 T AT 01976285T AT 01976285 T AT01976285 T AT 01976285T AT E472533 T1 ATE472533 T1 AT E472533T1
Authority
AT
Austria
Prior art keywords
sub
sup
alkyl
img
character
Prior art date
Application number
AT01976285T
Other languages
English (en)
Inventor
Gurdip Bhalay
Trevor Howe
Grand Darren Le
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0024675A external-priority patent/GB0024675D0/en
Priority claimed from GB0120549A external-priority patent/GB0120549D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE472533T1 publication Critical patent/ATE472533T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT01976285T 2000-10-09 2001-10-08 N-(4-aryloxypiperidin-1-ylalkyl)zimtsäureamide als ccr3-rezeptorantagonisten ATE472533T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0024675A GB0024675D0 (en) 2000-10-09 2000-10-09 Organic compounds
GB0120549A GB0120549D0 (en) 2001-08-23 2001-08-23 Organic compounds
PCT/EP2001/011627 WO2002030898A1 (en) 2000-10-09 2001-10-08 N-(4-aryloxypiperidin-1-ylalkyl) cinnamic amides as ccr33 receptor antagonists

Publications (1)

Publication Number Publication Date
ATE472533T1 true ATE472533T1 (de) 2010-07-15

Family

ID=26245127

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01976285T ATE472533T1 (de) 2000-10-09 2001-10-08 N-(4-aryloxypiperidin-1-ylalkyl)zimtsäureamide als ccr3-rezeptorantagonisten

Country Status (12)

Country Link
US (1) US7034042B2 (de)
EP (1) EP1330436B1 (de)
JP (1) JP4199539B2 (de)
CN (1) CN1209351C (de)
AT (1) ATE472533T1 (de)
AU (1) AU2001295601A1 (de)
BR (1) BR0114485A (de)
CA (1) CA2423296C (de)
DE (1) DE60142484D1 (de)
ES (1) ES2348290T3 (de)
PT (1) PT1330436E (de)
WO (1) WO2002030898A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117387D0 (en) * 2001-07-17 2001-09-05 Novartis Ag Organic compounds
CN100360521C (zh) * 2002-04-25 2008-01-09 帝人株式会社 具有ccr3拮抗作用的4,4-二取代的哌啶衍生物
ZA200803939B (en) * 2005-11-24 2009-10-28 Eisai R&D Man Co Ltd Morpholine type cinnamide compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673684A (en) * 1984-04-04 1987-06-16 Terumo Corporation Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
JPS63139124A (ja) 1986-12-01 1988-06-10 Terumo Corp 腎炎治療剤
JPS63179869A (ja) 1987-01-20 1988-07-23 Dainippon Pharmaceut Co Ltd ピペリジン誘導体
DE19756235A1 (de) 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide
KR20010108394A (ko) 1999-03-26 2001-12-07 다비드 에 질레스 신규 화합물
TWI227231B (en) * 2000-07-12 2005-02-01 Novartis Ag 4-benzoyl-piperidine derivatives for treating conditions mediated by CCR-3

Also Published As

Publication number Publication date
PT1330436E (pt) 2010-10-11
CA2423296A1 (en) 2002-04-18
AU2001295601A1 (en) 2002-04-22
CN1468222A (zh) 2004-01-14
US7034042B2 (en) 2006-04-25
BR0114485A (pt) 2003-11-18
JP4199539B2 (ja) 2008-12-17
US20040087621A1 (en) 2004-05-06
WO2002030898A1 (en) 2002-04-18
EP1330436B1 (de) 2010-06-30
EP1330436A1 (de) 2003-07-30
DE60142484D1 (de) 2010-08-12
ES2348290T3 (es) 2010-12-02
CA2423296C (en) 2009-12-29
JP2004511467A (ja) 2004-04-15
CN1209351C (zh) 2005-07-06

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