BR0113637A - Composto, processo para a preparação desse composto, composição farmacêutica que compreende o mesmo, utilização do composto, processo para o tratamento e/ou profilaxia de enfermidade que estão associadas com a atividade de receptor melanocortin-4 - Google Patents

Composto, processo para a preparação desse composto, composição farmacêutica que compreende o mesmo, utilização do composto, processo para o tratamento e/ou profilaxia de enfermidade que estão associadas com a atividade de receptor melanocortin-4

Info

Publication number
BR0113637A
BR0113637A BR0113637-2A BR0113637A BR0113637A BR 0113637 A BR0113637 A BR 0113637A BR 0113637 A BR0113637 A BR 0113637A BR 0113637 A BR0113637 A BR 0113637A
Authority
BR
Brazil
Prior art keywords
compound
melanocortin
preparing
pharmaceutical composition
treating
Prior art date
Application number
BR0113637-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Li Chen
Adrian Wai-Hing Cheung
Xin-Jie Chu
Waleed Danho
Joseph Swistok
Yao Wang
Keith Alan Yagaloff
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0113637A publication Critical patent/BR0113637A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR0113637-2A 2000-08-30 2001-08-21 Composto, processo para a preparação desse composto, composição farmacêutica que compreende o mesmo, utilização do composto, processo para o tratamento e/ou profilaxia de enfermidade que estão associadas com a atividade de receptor melanocortin-4 BR0113637A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22918400P 2000-08-30 2000-08-30
PCT/EP2001/009630 WO2002018437A2 (en) 2000-08-30 2001-08-21 Cyclic peptides having melanocortin-4 receptor agonist activity

Publications (1)

Publication Number Publication Date
BR0113637A true BR0113637A (pt) 2004-02-25

Family

ID=22860145

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113637-2A BR0113637A (pt) 2000-08-30 2001-08-21 Composto, processo para a preparação desse composto, composição farmacêutica que compreende o mesmo, utilização do composto, processo para o tratamento e/ou profilaxia de enfermidade que estão associadas com a atividade de receptor melanocortin-4

Country Status (35)

Country Link
US (1) US7045591B2 (https=)
EP (1) EP1315750B1 (https=)
JP (1) JP4217069B2 (https=)
KR (1) KR100483300B1 (https=)
CN (1) CN100491396C (https=)
AR (2) AR030504A1 (https=)
AT (1) ATE353918T1 (https=)
AU (2) AU2001284026B2 (https=)
BR (1) BR0113637A (https=)
CA (1) CA2420058C (https=)
CY (1) CY1106562T1 (https=)
CZ (1) CZ2003584A3 (https=)
DE (1) DE60126624T2 (https=)
DK (1) DK1315750T3 (https=)
EC (1) ECSP034503A (https=)
ES (1) ES2280393T3 (https=)
HR (1) HRP20030126B1 (https=)
HU (1) HUP0303078A3 (https=)
IL (2) IL154575A0 (https=)
JO (1) JO2454B1 (https=)
MA (1) MA27681A1 (https=)
MX (1) MXPA03001721A (https=)
MY (1) MY137457A (https=)
NO (1) NO20030916L (https=)
NZ (1) NZ523989A (https=)
PA (1) PA8527201A1 (https=)
PE (1) PE20020483A1 (https=)
PL (1) PL366630A1 (https=)
PT (1) PT1315750E (https=)
RU (1) RU2239642C1 (https=)
SI (1) SI1315750T1 (https=)
TW (1) TWI248941B (https=)
WO (1) WO2002018437A2 (https=)
YU (1) YU15603A (https=)
ZA (1) ZA200301015B (https=)

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US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7732451B2 (en) 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
US7655658B2 (en) 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7354923B2 (en) 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
WO2004005324A2 (en) 2002-07-09 2004-01-15 Palatin Technologies, Inc. Peptide composition for treatment of sexual dysfunction
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
KR20060026011A (ko) 2003-05-09 2006-03-22 노보 노르디스크 에이/에스 비만 치료용 펩티드
BRPI0409976A (pt) * 2003-05-09 2006-05-09 Novo Nordisk As composto, métodos para retardar a progressão de igt diabetes do tipo 2, para retardar a progressão de diabetes do tipo 2 para diabetes que requer insulina, para tratar obesidade ou prevenir excesso de peso para regular o apetite para induzir saciedade, para prevenir ganho de peso após se ter tido sucesso em perder peso, para aumentar dispêndio de energia, para tratar uma doença ou estado e para tratar bulimia, composição farmacêutica, e, uso de um composto
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US7084111B2 (en) 2003-06-23 2006-08-01 University Of Florida Research Foundation, Inc. Melanocortin receptor templates, peptides, and use thereof
EP1670815A2 (en) * 2003-09-30 2006-06-21 Novo Nordisk A/S Melanocortin receptor agonists
US7550602B1 (en) 2004-01-14 2009-06-23 Palatin Technologies, Inc. Small molecule compositions for sexual dysfunction
US6974187B2 (en) * 2004-01-28 2005-12-13 Tachi-S Co., Ltd. Vehicle seat structure
US20070123453A1 (en) * 2004-03-29 2007-05-31 Heiman Mark L Uses of melanocortin-4 receptor (mc4r) agonist peptides administered by continuous infusion
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US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
EP1809665A2 (en) * 2004-11-04 2007-07-25 Novo Nordisk A/S Mc4r selective peptides and their use in the treatment of obesity
JP2008519008A (ja) * 2004-11-04 2008-06-05 ノボ ノルディスク アクティーゼルスカブ 肥満症の治療に使用するためのペプチド
EP1809666A2 (en) * 2004-11-04 2007-07-25 Novo Nordisk A/S Peptides for use in the treating obesity
JP2008519009A (ja) * 2004-11-04 2008-06-05 ノボ ノルディスク アクティーゼルスカブ 肥満症の治療に使用するためのペプチド
CN101203527A (zh) * 2005-05-31 2008-06-18 耶路撒冷希伯来大学伊森姆研究发展公司 主链环化的促黑皮质素激素（αMSH）类似物
US20090042790A1 (en) * 2005-06-13 2009-02-12 Nastech Pharmaceutical Company Inc. Transmucosal delivery of peptide derivatives
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ES2618315T3 (es) 2007-05-25 2017-06-21 Ipsen Pharma S.A.S. Ligandos del receptor de melanocortina modificados con hidantoína
US8258313B2 (en) 2007-07-19 2012-09-04 Tokuyama Corporation Compound having hydantoin ring and method of producing the same
ES2464102T3 (es) 2008-03-27 2014-05-30 Grünenthal GmbH Derivados de 4-aminociclohexano sustituidos
EP2280941B1 (de) * 2008-03-27 2015-05-06 Grünenthal GmbH (hetero-)aryl-cyclohexan-derivate
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Also Published As

Publication number Publication date
CN1451017A (zh) 2003-10-22
AR030504A1 (es) 2003-08-20
DE60126624D1 (de) 2007-03-29
PT1315750E (pt) 2007-05-31
IL154575A0 (en) 2003-09-17
WO2002018437A3 (en) 2002-06-06
MA27681A1 (fr) 2006-01-02
SI1315750T1 (sl) 2007-06-30
CY1106562T1 (el) 2012-01-25
TWI248941B (en) 2006-02-11
AR061422A2 (es) 2008-08-27
DK1315750T3 (da) 2007-06-11
JP4217069B2 (ja) 2009-01-28
US7045591B2 (en) 2006-05-16
ECSP034503A (es) 2003-04-25
NO20030916D0 (no) 2003-02-27
YU15603A (sh) 2006-05-25
AU2001284026B2 (en) 2007-03-01
JO2454B1 (en) 2008-10-09
HRP20030126A2 (en) 2005-10-31
ZA200301015B (en) 2004-05-05
JP2004507558A (ja) 2004-03-11
ATE353918T1 (de) 2007-03-15
WO2002018437A2 (en) 2002-03-07
CZ2003584A3 (cs) 2003-08-13
KR100483300B1 (ko) 2005-04-15
CN100491396C (zh) 2009-05-27
HUP0303078A2 (hu) 2003-12-29
PA8527201A1 (es) 2002-04-25
KR20030061788A (ko) 2003-07-22
PE20020483A1 (es) 2002-06-06
AU8402601A (en) 2002-03-13
RU2239642C1 (ru) 2004-11-10
ES2280393T3 (es) 2007-09-16
CA2420058A1 (en) 2002-03-07
NO20030916L (no) 2003-02-27
CA2420058C (en) 2009-04-07
NZ523989A (en) 2004-08-27
HRP20030126B1 (en) 2009-01-31
EP1315750A2 (en) 2003-06-04
MY137457A (en) 2009-01-30
US20020143141A1 (en) 2002-10-03
EP1315750B1 (en) 2007-02-14
MXPA03001721A (es) 2003-05-27
DE60126624T2 (de) 2007-11-22
HUP0303078A3 (en) 2012-02-28
IL154575A (en) 2008-12-29
PL366630A1 (en) 2005-02-07

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