BR0015962A - Compostos tendo ligações multiplas que são agonistas de receptor adrenérgico (beta)2 úteis no tratamento e prevenção de doenças respiratórias - Google Patents
Compostos tendo ligações multiplas que são agonistas de receptor adrenérgico (beta)2 úteis no tratamento e prevenção de doenças respiratóriasInfo
- Publication number
- BR0015962A BR0015962A BR0015962-0A BR0015962A BR0015962A BR 0015962 A BR0015962 A BR 0015962A BR 0015962 A BR0015962 A BR 0015962A BR 0015962 A BR0015962 A BR 0015962A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- prevention
- compounds
- respiratory diseases
- adrenergic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 3
- 208000023504 respiratory system disease Diseases 0.000 title abstract 2
- 230000001800 adrenalinergic effect Effects 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 239000000048 adrenergic agonist Substances 0.000 abstract 2
- 229940126157 adrenergic receptor agonist Drugs 0.000 abstract 2
- 208000001738 Nervous System Trauma Diseases 0.000 abstract 1
- 208000005107 Premature Birth Diseases 0.000 abstract 1
- 206010036590 Premature baby Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000028412 nervous system injury Diseases 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Vehicle Body Suspensions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Abstract
"COMPOSTOS TENDO LIGAçõES MúLTIPLAS QUE SãO AGONISTAS DE RECEPTOR ADRENéRGICO <225>2 úTEIS NO TRATAMENTO E PREVENçãO DE DOENçAS RESPIRATóRIAS". São descritos compostos tendo ligações múltiplas que são agonistas de receptor adrenérgico <225>2 úteis no tratamento e prevenção de doenças respiratórias tais como asma, bronquite. Eles são também úteis no tratamento de lesão do sistema nervoso e no parto prematuro.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45761899A | 1999-12-08 | 1999-12-08 | |
US09/637,899 US6576793B1 (en) | 1999-12-08 | 2000-08-14 | β2-adrenergic receptor agonists |
PCT/US2000/033057 WO2001042193A1 (en) | 1999-12-08 | 2000-12-06 | β2-ADRENERGIC RECEPTOR AGONISTS |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0015962A true BR0015962A (pt) | 2002-07-30 |
Family
ID=27038674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0015962-0A BR0015962A (pt) | 1999-12-08 | 2000-12-06 | Compostos tendo ligações multiplas que são agonistas de receptor adrenérgico (beta)2 úteis no tratamento e prevenção de doenças respiratórias |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1235787B1 (pt) |
KR (1) | KR20070039968A (pt) |
CN (1) | CN1402702A (pt) |
AT (1) | ATE253039T1 (pt) |
AU (1) | AU781466B2 (pt) |
BR (1) | BR0015962A (pt) |
CA (1) | CA2391293C (pt) |
CZ (1) | CZ20021831A3 (pt) |
DE (1) | DE60006280T2 (pt) |
DK (1) | DK1235787T3 (pt) |
EA (1) | EA004263B1 (pt) |
ES (1) | ES2208453T3 (pt) |
HR (1) | HRP20020381A2 (pt) |
HU (1) | HUP0203638A3 (pt) |
IL (1) | IL149317A0 (pt) |
IS (1) | IS2164B (pt) |
MX (1) | MXPA02005599A (pt) |
NO (1) | NO327630B1 (pt) |
OA (1) | OA11558A (pt) |
PT (1) | PT1235787E (pt) |
SK (1) | SK287036B6 (pt) |
TR (1) | TR200302010T4 (pt) |
WO (1) | WO2001042193A1 (pt) |
Families Citing this family (133)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1487417A4 (en) | 2001-09-17 | 2010-03-17 | Glaxo Group Ltd | DRY POWDER DRUG FORMULATIONS |
TWI249515B (en) * | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
WO2003042160A1 (en) * | 2001-11-13 | 2003-05-22 | Theravance, Inc. | Aryl aniline beta-2 adrenergic receptor agonists |
EP1507754A1 (en) | 2002-05-28 | 2005-02-23 | Theravance, Inc. | Alkoxy aryl beta-2 adrenergic receptor agonists |
TW200409746A (en) * | 2002-07-26 | 2004-06-16 | Theravance Inc | Crystalline β2 adrenergic receptor agonist |
US6844362B2 (en) | 2002-10-11 | 2005-01-18 | Pfizer Inc | Indole derivatives useful for the treatment of diseases |
EP1622875B1 (en) | 2003-05-08 | 2009-12-02 | Theravance, Inc. | Crystalline forms of an arylaniline beta-2 adrenergic receptor agonist |
TW200510277A (en) | 2003-05-27 | 2005-03-16 | Theravance Inc | Crystalline form of β2-adrenergic receptor agonist |
US7067541B2 (en) | 2003-06-04 | 2006-06-27 | Pfizer Inc | 2-amino-pyridine derivatives useful for the treatment of diseases |
US7375100B2 (en) | 2003-06-04 | 2008-05-20 | Pfizer Inc | 2-amino-pyridine derivatives useful for the treatment of diseases |
GB0316290D0 (en) | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
ES2449718T3 (es) | 2003-08-11 | 2014-03-20 | Glaxo Group Limited | Inhalador de dosis farmacéutica medida y procedimiento relacionados con el mismo |
TW200526547A (en) | 2003-09-22 | 2005-08-16 | Theravance Inc | Amino-substituted ethylamino β2 adrenergic receptor agonists |
TW200531692A (en) | 2004-01-12 | 2005-10-01 | Theravance Inc | Aryl aniline derivatives as β2 adrenergic receptor agonists |
GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
DK1708992T3 (da) | 2004-01-22 | 2007-11-05 | Pfizer | Sulfonamidderivater til behandling af sygdomme |
EP1577291A1 (en) * | 2004-03-17 | 2005-09-21 | Pfizer Limited | Phenylethanolamine derivatives as beta-2 agonists |
EA200601510A1 (ru) * | 2004-03-17 | 2007-04-27 | Пфайзер Инк. | Производные фенилэтаноламина в качестве бета-2-агонистов |
GB0425054D0 (en) * | 2004-03-23 | 2004-12-15 | Pfizer Ltd | Formamide derivatives for the treatment of diseases |
BRPI0507877A (pt) * | 2004-03-23 | 2007-07-24 | Pfizer | derivados de formamida, composição farmacêutica, uso dos mesmos e combinação |
CA2561400A1 (en) * | 2004-04-02 | 2005-10-13 | Glaxo Group Limited | Chemical process and new crystalline form |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
US20080039495A1 (en) * | 2004-06-03 | 2008-02-14 | Linsell Martin S | Diamine Beta2 Adrenergic Receptor Agonists |
EP1778638A1 (en) | 2004-07-21 | 2007-05-02 | Theravance, Inc. | Diaryl ether beta2 adrenergic receptor agonists |
GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
WO2006066907A1 (en) * | 2004-12-21 | 2006-06-29 | Glaxo Group Limited | Pharmaceutical formulations |
EP1841780B1 (en) | 2005-01-10 | 2011-07-27 | Glaxo Group Limited | Androstane 17-alpha-carbonate derivatives for use in the treatment of allergic and inflammatory conditions |
PE20061351A1 (es) | 2005-03-25 | 2007-01-14 | Glaxo Group Ltd | COMPUESTOS 8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA 2,4,8-TRISUSTITUIDOS COMO INHIBIDORES DE LA QUINASA CSBP/RK/p38 |
GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
US7994211B2 (en) | 2005-08-08 | 2011-08-09 | Argenta Discovery Limited | Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses |
GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
TW200738658A (en) | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
JP5006330B2 (ja) | 2005-10-21 | 2012-08-22 | ノバルティス アーゲー | Il13に対するヒト抗体および治療的使用 |
TW200730498A (en) | 2005-12-20 | 2007-08-16 | Glaxo Group Ltd | Compounds |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
TW200745084A (en) * | 2006-03-08 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
AU2007242851A1 (en) | 2006-04-20 | 2007-11-01 | Glaxo Group Limited | Novel compounds |
AR060607A1 (es) | 2006-04-21 | 2008-07-02 | Novartis Ag | Derivados de purina,composiciones farmaceuticas que los contienen, metodo de preparacion y usos en enfermedades obstructivas o inflamatorias de las vias respiratorias. |
GB0611587D0 (en) | 2006-06-12 | 2006-07-19 | Glaxo Group Ltd | Novel compounds |
CL2007001829A1 (es) | 2006-06-23 | 2008-01-25 | Smithkline Beecham Corp | P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc. |
ES2302447B1 (es) * | 2006-10-20 | 2009-06-12 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
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ATE493174T1 (de) | 2007-01-10 | 2011-01-15 | Irm Llc | Verbindungen und zusammensetzungen als kanal- aktivierende proteasehemmer |
GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
ES2306595B1 (es) | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
US20100239551A1 (en) | 2007-02-09 | 2010-09-23 | Irm Llc | Compounds and compositions as channel activating protease inhibitors |
PE20081889A1 (es) | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
ES2361595T3 (es) | 2007-05-07 | 2011-06-20 | Novartis Ag | Compuestos orgánicos. |
ES2320961B1 (es) | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
CN101939054B (zh) | 2007-12-10 | 2014-10-29 | 诺华股份有限公司 | 有机化合物 |
BRPI0906838A2 (pt) | 2008-01-11 | 2015-07-14 | Novartis Ag | Pirimidinas como inibidores de quinase |
KR20160129109A (ko) | 2008-05-23 | 2016-11-08 | 아미라 파마슈티칼스 인코포레이티드 | 5-리폭시게나아제 활성화 단백질 억제제 |
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JP2012520845A (ja) | 2009-03-17 | 2012-09-10 | グラクソ グループ リミテッド | Itk阻害剤として使用されるピリミジン誘導体 |
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BE630296A (pt) * | 1962-03-31 | |||
AT322534B (de) * | 1972-03-16 | 1975-05-26 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen optisch aktiven 1-(4'-amino-3'-halogenphenyl)-2-aminoäthanolen und deren säureadditionssalzen |
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JPH10152460A (ja) * | 1996-11-21 | 1998-06-09 | Kissei Pharmaceut Co Ltd | 2−アミノ−1−(4−ヒドロキシ−2−メチルフェニル)プロパノール誘導体 |
US6541669B1 (en) * | 1998-06-08 | 2003-04-01 | Theravance, Inc. | β2-adrenergic receptor agonists |
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2000
- 2000-12-06 AU AU22546/01A patent/AU781466B2/en not_active Ceased
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- 2000-12-06 BR BR0015962-0A patent/BR0015962A/pt not_active Application Discontinuation
- 2000-12-06 CA CA002391293A patent/CA2391293C/en not_active Expired - Fee Related
- 2000-12-06 HU HU0203638A patent/HUP0203638A3/hu unknown
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- 2000-12-06 WO PCT/US2000/033057 patent/WO2001042193A1/en active IP Right Grant
- 2000-12-06 DK DK00986271T patent/DK1235787T3/da active
- 2000-12-06 MX MXPA02005599A patent/MXPA02005599A/es active IP Right Grant
- 2000-12-06 CZ CZ20021831A patent/CZ20021831A3/cs unknown
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- 2000-12-06 IL IL14931700A patent/IL149317A0/xx unknown
- 2000-12-06 PT PT00986271T patent/PT1235787E/pt unknown
- 2000-12-06 EA EA200200647A patent/EA004263B1/ru not_active IP Right Cessation
- 2000-12-06 TR TR2003/02010T patent/TR200302010T4/xx unknown
- 2000-12-06 DE DE60006280T patent/DE60006280T2/de not_active Expired - Lifetime
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- 2000-12-06 KR KR1020077004447A patent/KR20070039968A/ko not_active Application Discontinuation
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EA004263B1 (ru) | 2004-02-26 |
NO20022655L (no) | 2002-06-05 |
EP1235787A1 (en) | 2002-09-04 |
IL149317A0 (en) | 2002-11-10 |
HUP0203638A3 (en) | 2003-04-28 |
DK1235787T3 (da) | 2004-03-08 |
AU2254601A (en) | 2001-06-18 |
DE60006280T2 (de) | 2004-07-29 |
HUP0203638A2 (hu) | 2003-02-28 |
CA2391293A1 (en) | 2001-06-14 |
EP1235787B1 (en) | 2003-10-29 |
AU781466B2 (en) | 2005-05-26 |
NO20022655D0 (no) | 2002-06-05 |
CZ20021831A3 (cs) | 2002-11-13 |
DE60006280D1 (de) | 2003-12-04 |
IS2164B (is) | 2006-11-15 |
ES2208453T3 (es) | 2004-06-16 |
EA200200647A1 (ru) | 2002-12-26 |
IS6350A (is) | 2002-04-19 |
SK287036B6 (sk) | 2009-10-07 |
TR200302010T4 (tr) | 2004-01-21 |
PT1235787E (pt) | 2004-03-31 |
ATE253039T1 (de) | 2003-11-15 |
OA11558A (en) | 2004-06-03 |
CN1402702A (zh) | 2003-03-12 |
SK9922002A3 (en) | 2002-11-06 |
CA2391293C (en) | 2008-12-30 |
WO2001042193A1 (en) | 2001-06-14 |
KR20070039968A (ko) | 2007-04-13 |
HRP20020381A2 (en) | 2005-12-31 |
NO327630B1 (no) | 2009-09-07 |
MXPA02005599A (es) | 2002-09-18 |
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