BR0100689A - Fabricação de ácido cìclico - Google Patents

Fabricação de ácido cìclico

Info

Publication number
BR0100689A
BR0100689A BR0100689-4A BR0100689A BR0100689A BR 0100689 A BR0100689 A BR 0100689A BR 0100689 A BR0100689 A BR 0100689A BR 0100689 A BR0100689 A BR 0100689A
Authority
BR
Brazil
Prior art keywords
dibenzyl
oxo
cis
imidazolidinedicarboxylic
metal salt
Prior art date
Application number
BR0100689-4A
Other languages
English (en)
Inventor
Juergen Fleckenstein
Bernd Kraemer
Joachim Veits
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0100689A publication Critical patent/BR0100689A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Patente de Invenção: <B>"FABRICAçãO DE áCIDO CìCLICO"<D>. Processo para produção de ácido 2-oxo-1,3-dibenzil-4,5-imidazolidinadicarboxílico e, respectivamente de anidrido de ácido 2-oxo-1,3-dibenzil-4,5-imidazolidinadicarboxílico partindo de um sal de metal dial-calino de ácido meso-2,3-bis(benzilamino)succínico que compreende reação do sal de metal dialcalino de ácido meso-2,3-bis(benzilamino)succínico com clorofomiato de fenila em um sistema de solvente monofásico, consistindo em uma mistura de cerca de 2:1 a 1:1 de um éter miscível em água e solução de hidróxido de metal alcalino aquosa, a uma temperatura não excedendo cerca de 40°C e convertendo o sal de metal dialcalino de ácido 2-oxo-1,3-dibenzil-cis-4,5-imidazolidinadicarboxílico, por acidificação no ácido de 1-oxo-1,3-dibenzil-cis-4,5-imidazolidinadicarboxílico desejado e isolando este ou convertendo por aquecimento com anidrido acético, em um hidrocarboneto aromático como o solvente orgânico no anidrido de ácido 2-oxo-1,3-dibenzil-cis-4,5-imidazolidinadicarboxílico desejado e isolando o mesmo. Cada produto é um intermediário importante no processo de múltiplas etapas para a fabricação de biotina (vitamina H).
BR0100689-4A 2000-02-25 2001-02-21 Fabricação de ácido cìclico BR0100689A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH3742000 2000-02-25

Publications (1)

Publication Number Publication Date
BR0100689A true BR0100689A (pt) 2001-09-25

Family

ID=4513524

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0100689-4A BR0100689A (pt) 2000-02-25 2001-02-21 Fabricação de ácido cìclico

Country Status (10)

Country Link
US (1) US6291681B1 (pt)
EP (1) EP1127879B1 (pt)
JP (1) JP4833419B2 (pt)
KR (1) KR100776104B1 (pt)
CN (1) CN1155578C (pt)
AT (1) ATE296291T1 (pt)
BR (1) BR0100689A (pt)
CA (1) CA2337620A1 (pt)
DE (1) DE50106283D1 (pt)
ES (1) ES2241699T3 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200300676A (en) * 2001-12-04 2003-06-16 Tanabe Seiyaku Co Biotin intermediate and its production
US20060074248A1 (en) * 2003-04-22 2006-04-06 Christof Wehrli Process for the stereoselective synthesis of lactones
US7032407B2 (en) 2003-06-27 2006-04-25 General Electric Company Methods and apparatus for refrigerator compartment
US7463481B2 (en) * 2005-03-09 2008-12-09 Hewlett-Packard Development Company, L.P. Computer with hinge post and hinge mount and related methods
CN113801125B (zh) * 2021-09-16 2023-11-03 安徽泰格维生素实业有限公司 一种环酸酐的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS518270A (en) 1974-07-11 1976-01-23 Sumitomo Chemical Co 22 okiso imidazorijin 4*55 jikarubonsanruino seiho
US5151525A (en) * 1991-06-18 1992-09-29 Ppg Industries, Inc. Process for producing 2-oxo-1,3-dibenzyl-4,5-cis-imidazolidinedicarboxylic acid
EP1081139A3 (de) * 1999-08-27 2001-09-05 F. Hoffmann-La Roche Ag Herstellung einer Imidazolidindicarbonsaüre

Also Published As

Publication number Publication date
EP1127879B1 (de) 2005-05-25
EP1127879A1 (de) 2001-08-29
JP4833419B2 (ja) 2011-12-07
CA2337620A1 (en) 2001-08-25
US6291681B1 (en) 2001-09-18
JP2001278867A (ja) 2001-10-10
ES2241699T3 (es) 2005-11-01
US20010020101A1 (en) 2001-09-06
KR100776104B1 (ko) 2007-11-15
DE50106283D1 (de) 2005-06-30
KR20010085473A (ko) 2001-09-07
CN1155578C (zh) 2004-06-30
CN1310176A (zh) 2001-08-29
ATE296291T1 (de) 2005-06-15

Similar Documents

Publication Publication Date Title
BR0100689A (pt) Fabricação de ácido cìclico
KR100788529B1 (ko) 3-(1-히드록시-펜틸리덴)-5-니트로-3ｈ-벤조푸란-2-온,그의 제조 방법 및 용도
HUP0204187A2 (hu) Eljárás 1-oxo-1,3-dihidro-izobenzofurán-5-karbonsav előállítására és a vegyület alkalmazása citaloprom szintézisére
AU3498999A (en) Process and intermediates for the manufacture of pyridine-2,3-dicarboxylate compounds
JPS61158966A (ja) 置換されたおよび未置換の２−カルバモイルニコチン酸類および３−キノリンカルボン酸類の製造方法
Khoramdelan et al. Synthesis of New Functionalized 1, 4-Dihydroquinolines and Pyrimido [4, 5-b] quinolines
CN106905177A (zh) 一种2‑氨基‑3‑联苯基丙酸乙酯衍生物盐酸盐的制备方法
DE50101761D1 (de) Verfahren zur herstellung von 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-yl-essigsäure
RU2561730C1 (ru) Способ получения 3-хлорметил-4-метоксибензальдегида
CN104030938A (zh) 盐酸丙帕他莫的制备方法
RU1779243C (ru) Способ получени 3-фтор-4-аминофенола
US4925970A (en) Process for producing cyclohexadiene thioether
EP0101004B2 (en) Process for preparing 4-oxo-4, 5, 6, 7-tetrahydroindole derivative
GB1093103A (en) Process for preparing alkene-sulphonates
CN108047177A (zh) 一步合成苯并呋喃类β-脱氢非天然氨基酸的方法
US4213905A (en) Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts
KR101590106B1 (ko) 1-옥사세팔로스포린 유도체의 제조방법
KR102658673B1 (ko) (1r,3s)-3-아미노기-1-사이클로펜탄올 및 그 염의 제조방법
CN103880693B (zh) 一种γ-氨基丁酸酯衍生物的合成方法
CN106866544B (zh) 2-(2-羟基苯基)-1h-苯并咪唑及其衍生物和合成方法及应用
US2545433A (en) 3-nitro-4-hydroxy-thiophanes
BR0004570A (pt) Produção de um ácido cìclico
SU421694A1 (ru) Способ получения 3-циклогексил-5,6-триметиленурацила
CN110642818A (zh) 一种制备苯并呋喃-2-甲酰胺类化合物的方法
SU1074855A1 (ru) Способ получени (-)-2-пентен-4-ола

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]