BR0015786A - 1,2,3,4,5,6-hexaidro-2,6-metano-3-benzazocinas substituìdas e seu uso como composições farmacêuticas - Google Patents
1,2,3,4,5,6-hexaidro-2,6-metano-3-benzazocinas substituìdas e seu uso como composições farmacêuticasInfo
- Publication number
- BR0015786A BR0015786A BR0015786-4A BR0015786A BR0015786A BR 0015786 A BR0015786 A BR 0015786A BR 0015786 A BR0015786 A BR 0015786A BR 0015786 A BR0015786 A BR 0015786A
- Authority
- BR
- Brazil
- Prior art keywords
- benzazocines
- substituted
- pharmaceutical compositions
- hexahydro
- methane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/06—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"1,2,3,4,5,6-HEXAIDRO-2,6-METANO-3-BENZAZOCINAS SUBSTITUìDAS E SEU USO COMO COMPOSIçõES FARMACêUTICAS". A presente invenção refere-se a 1,2,3,4,5,6-hexaidro-2,6metano-3-benzazocinas substituídas da fórmula geral 1 em que os grupos R^ 1^, R^ 2^, R^ 3^, R^ 4^, R^ 5^, R^ 6^, X e A podem ter os significados dados no relatório e nas reivindicações, processos para a preparação deles e seu uso como composições farmacêuticas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19957156A DE19957156A1 (de) | 1999-11-27 | 1999-11-27 | Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel |
PCT/EP2000/011585 WO2001051471A1 (de) | 1999-11-27 | 2000-11-21 | Substituierte 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine und ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0015786A true BR0015786A (pt) | 2002-08-13 |
Family
ID=7930562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0015786-4A Expired - Fee Related BR0015786A (pt) | 1999-11-27 | 2000-11-21 | 1,2,3,4,5,6-hexaidro-2,6-metano-3-benzazocinas substituìdas e seu uso como composições farmacêuticas |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP1235809B1 (pt) |
JP (1) | JP2003519687A (pt) |
KR (1) | KR20020058042A (pt) |
CN (1) | CN1177825C (pt) |
AR (1) | AR026586A1 (pt) |
AT (1) | ATE254108T1 (pt) |
AU (1) | AU5789701A (pt) |
BG (1) | BG106682A (pt) |
BR (1) | BR0015786A (pt) |
CA (1) | CA2383114C (pt) |
CO (1) | CO5251469A1 (pt) |
CZ (1) | CZ20022120A3 (pt) |
DE (2) | DE19957156A1 (pt) |
DK (1) | DK1235809T3 (pt) |
EA (1) | EA005681B1 (pt) |
EE (1) | EE200200267A (pt) |
ES (1) | ES2210036T3 (pt) |
HK (1) | HK1052176A1 (pt) |
HR (1) | HRP20020460A2 (pt) |
HU (1) | HUP0204169A3 (pt) |
IL (1) | IL149607A0 (pt) |
MX (1) | MXPA02003822A (pt) |
NO (1) | NO20022457L (pt) |
NZ (1) | NZ519758A (pt) |
PL (1) | PL355493A1 (pt) |
PT (1) | PT1235809E (pt) |
SK (1) | SK9302002A3 (pt) |
TR (1) | TR200302031T4 (pt) |
UA (1) | UA72566C2 (pt) |
UY (1) | UY26448A1 (pt) |
WO (1) | WO2001051471A1 (pt) |
YU (1) | YU37902A (pt) |
ZA (1) | ZA200204056B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6683089B2 (en) | 2002-02-02 | 2004-01-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | N-allyoxyethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-10-ols |
DE10204276A1 (de) * | 2002-02-02 | 2003-08-07 | Boehringer Ingelheim Pharma | N-Allyloxyethyl-1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel |
US10138207B2 (en) * | 2012-11-09 | 2018-11-27 | Purdue Pharma, L.P. | Benzomorphan analogs and the use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4121821A1 (de) * | 1991-07-02 | 1993-01-14 | Boehringer Ingelheim Kg | Neue benzomorphane und ihre verwendung als arzneimittel |
US5354758A (en) * | 1992-12-16 | 1994-10-11 | Japan Tobacco Inc. | Benzomorphans useful as NMDA receptor antagonists |
DE19740110A1 (de) * | 1997-09-12 | 1999-03-18 | Boehringer Ingelheim Pharma | Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE19907874A1 (de) * | 1999-02-23 | 2000-08-24 | Boehringer Ingelheim Pharma | N-(5-Phenyl-tetrahydrofuranyl)methyl- und N-(6-Phenyl-tetrahydropyranyl)methyl substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
-
1999
- 1999-11-27 DE DE19957156A patent/DE19957156A1/de not_active Withdrawn
-
2000
- 2000-11-21 AU AU57897/01A patent/AU5789701A/en not_active Abandoned
- 2000-11-21 WO PCT/EP2000/011585 patent/WO2001051471A1/de not_active Application Discontinuation
- 2000-11-21 ES ES00993781T patent/ES2210036T3/es not_active Expired - Lifetime
- 2000-11-21 EE EEP200200267A patent/EE200200267A/xx unknown
- 2000-11-21 AT AT00993781T patent/ATE254108T1/de not_active IP Right Cessation
- 2000-11-21 KR KR1020027006752A patent/KR20020058042A/ko not_active Application Discontinuation
- 2000-11-21 TR TR2003/02031T patent/TR200302031T4/xx unknown
- 2000-11-21 CN CNB008162530A patent/CN1177825C/zh not_active Expired - Fee Related
- 2000-11-21 NZ NZ519758A patent/NZ519758A/en unknown
- 2000-11-21 BR BR0015786-4A patent/BR0015786A/pt not_active Expired - Fee Related
- 2000-11-21 SK SK930-2002A patent/SK9302002A3/sk unknown
- 2000-11-21 EA EA200200491A patent/EA005681B1/ru not_active IP Right Cessation
- 2000-11-21 JP JP2001551853A patent/JP2003519687A/ja active Pending
- 2000-11-21 PL PL00355493A patent/PL355493A1/xx not_active Application Discontinuation
- 2000-11-21 IL IL14960700A patent/IL149607A0/xx unknown
- 2000-11-21 UA UA2002065301A patent/UA72566C2/uk unknown
- 2000-11-21 YU YU37902A patent/YU37902A/sh unknown
- 2000-11-21 CZ CZ20022120A patent/CZ20022120A3/cs unknown
- 2000-11-21 HU HU0204169A patent/HUP0204169A3/hu unknown
- 2000-11-21 DE DE50004455T patent/DE50004455D1/de not_active Expired - Fee Related
- 2000-11-21 MX MXPA02003822A patent/MXPA02003822A/es unknown
- 2000-11-21 CA CA002383114A patent/CA2383114C/en not_active Expired - Fee Related
- 2000-11-21 PT PT00993781T patent/PT1235809E/pt unknown
- 2000-11-21 DK DK00993781T patent/DK1235809T3/da active
- 2000-11-21 EP EP00993781A patent/EP1235809B1/de not_active Expired - Lifetime
- 2000-11-23 AR ARP000106183A patent/AR026586A1/es not_active Suspension/Interruption
- 2000-11-24 CO CO00090163A patent/CO5251469A1/es not_active Application Discontinuation
- 2000-11-24 UY UY26448A patent/UY26448A1/es not_active Application Discontinuation
-
2002
- 2002-05-09 BG BG106682A patent/BG106682A/bg active Pending
- 2002-05-22 ZA ZA200204056A patent/ZA200204056B/en unknown
- 2002-05-24 NO NO20022457A patent/NO20022457L/no not_active Application Discontinuation
- 2002-05-24 HR HR20020460A patent/HRP20020460A2/hr not_active Application Discontinuation
-
2003
- 2003-06-11 HK HK03104095A patent/HK1052176A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |