BG64700B1 - Заместени 2-бензиламино-2-фенилацетамиди - Google Patents

Заместени 2-бензиламино-2-фенилацетамиди Download PDF

Info

Publication number
BG64700B1
BG64700B1 BG104569A BG10456900A BG64700B1 BG 64700 B1 BG64700 B1 BG 64700B1 BG 104569 A BG104569 A BG 104569A BG 10456900 A BG10456900 A BG 10456900A BG 64700 B1 BG64700 B1 BG 64700B1
Authority
BG
Bulgaria
Prior art keywords
benzylamino
phenylacetamide
compound
pharmaceutically acceptable
fluorobenzyloxy
Prior art date
Application number
BG104569A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104569A (en
Inventor
Paolo Pevarello
Mario Varasi
Patricia Salvati
Claes Post
Original Assignee
Newron Pharmaceuticals S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharmaceuticals S.P.A. filed Critical Newron Pharmaceuticals S.P.A.
Publication of BG104569A publication Critical patent/BG104569A/xx
Publication of BG64700B1 publication Critical patent/BG64700B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG104569A 1997-12-31 2000-06-28 Заместени 2-бензиламино-2-фенилацетамиди BG64700B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9727521.8A GB9727521D0 (en) 1997-12-31 1997-12-31 Substituted 2-benzylamino-2-phenyl-acetamide compounds

Publications (2)

Publication Number Publication Date
BG104569A BG104569A (en) 2001-02-28
BG64700B1 true BG64700B1 (bg) 2005-12-30

Family

ID=10824340

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104569A BG64700B1 (bg) 1997-12-31 2000-06-28 Заместени 2-бензиламино-2-фенилацетамиди

Country Status (23)

Country Link
US (1) US6303819B1 (fr)
EP (1) EP1044186B9 (fr)
JP (1) JP3839665B2 (fr)
KR (1) KR100629628B1 (fr)
AT (1) ATE319680T1 (fr)
BG (1) BG64700B1 (fr)
CA (1) CA2316082C (fr)
CZ (1) CZ296722B6 (fr)
DE (1) DE69833797T2 (fr)
EA (1) EA003097B1 (fr)
ES (1) ES2256976T3 (fr)
GB (1) GB9727521D0 (fr)
HK (1) HK1028021A1 (fr)
HR (1) HRP20000508B9 (fr)
HU (1) HUP0100184A3 (fr)
ID (1) ID26622A (fr)
IL (1) IL136735A0 (fr)
NO (1) NO327259B1 (fr)
NZ (1) NZ505441A (fr)
PL (1) PL194745B1 (fr)
PT (1) PT1044186E (fr)
TR (1) TR200001950T2 (fr)
WO (1) WO1999035123A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
JP2004517840A (ja) * 2000-11-27 2004-06-17 フアルマシア・イタリア・エツセ・ピー・アー フェニルアセトアミド−ピラゾール誘導体およびそれの抗腫瘍薬としての使用
US8084447B2 (en) 2001-09-03 2011-12-27 Newron Pharmaceuticals S.P.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use
US6667327B2 (en) 2002-02-04 2003-12-23 Hoffmann-La Roche Inc. Pyridine amido derivatives
EP1438956A1 (fr) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Dérivés alpha-aminoamides en tant qu'agents antimigraine
WO2004087125A1 (fr) * 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Derives d'acides amines en tant qu'inhibiteurs des canaux sodiques de mammiferes
EP1524267A1 (fr) * 2003-10-15 2005-04-20 Newron Pharmaceuticals S.p.A. Heterocycles benzyleaminoalkylene substitues
KR100856141B1 (ko) 2003-10-23 2008-09-03 에프. 호프만-라 로슈 아게 모노아민 산화효소 ｂ 저해제로서의 벤즈아제핀 유도체
EP1533298A1 (fr) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. Dérivés de 3-aminopyrrolidone
EP1533302A1 (fr) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. Dérivés de l'histidine
EP1535908A1 (fr) 2003-11-24 2005-06-01 Newron Pharmaceuticals S.p.A. Derives de N-acyl-N-benzylalkylendiamine
EP1588704A1 (fr) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Dérivés d'alpha-aminoamides utiles dans le traitement de l'acroparesthésie nocturne et des troubles de toxicomanie
KR101277520B1 (ko) * 2004-09-10 2013-06-21 뉴론 파마슈티칼즈 에스. 피. 에이. （할로벤질옥시）벤질아미노－프로판아미드를 포함하는 선택적 나트륨 및／또는 칼슘 채널 조절제로서 유용한 약제학적 조성물
RU2397160C9 (ru) 2005-12-22 2012-10-27 НЬЮРОН ФАРМАСЬЮТИКАЛЗ С.п.А. 2-фенилэтиламинопроизводные в качестве модуляторов кальциевых и/или натриевых каналов
EP1870097A1 (fr) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Dérivés d'alpha-aminoamide pour le traitement de troubles cognitifs
AU2008223916A1 (en) * 2007-03-05 2008-09-12 F. Hoffmann-La Roche Ag Aminoamides as orexin antagonists
US11111208B2 (en) * 2019-06-17 2021-09-07 RK Pharma Solutions LLC Process for the preparation of safinamide mesylate intermediate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688830A (en) * 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688830A (en) * 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain

Also Published As

Publication number Publication date
HRP20000508B1 (en) 2007-02-28
NZ505441A (en) 2001-12-21
EA200000728A1 (ru) 2001-02-26
JP3839665B2 (ja) 2006-11-01
HK1028021A1 (en) 2001-02-02
IL136735A0 (en) 2001-06-14
NO20003398D0 (no) 2000-06-29
CZ20002496A3 (cs) 2000-12-13
EP1044186B1 (fr) 2006-03-08
TR200001950T2 (tr) 2000-11-21
BG104569A (en) 2001-02-28
EP1044186B9 (fr) 2006-06-21
CA2316082A1 (fr) 1999-07-15
NO327259B1 (no) 2009-05-25
KR20010033779A (ko) 2001-04-25
PT1044186E (pt) 2006-07-31
HUP0100184A2 (hu) 2001-07-30
NO20003398L (no) 2000-08-02
JP2002500214A (ja) 2002-01-08
HUP0100184A3 (en) 2002-11-28
PL341514A1 (en) 2001-04-23
ATE319680T1 (de) 2006-03-15
HRP20000508B9 (en) 2008-05-31
DE69833797D1 (de) 2006-05-04
CZ296722B6 (cs) 2006-05-17
PL194745B1 (pl) 2007-06-29
EA003097B1 (ru) 2002-12-26
GB9727521D0 (en) 1998-02-25
HRP20000508A2 (en) 2001-02-28
CA2316082C (fr) 2006-02-07
ES2256976T3 (es) 2006-07-16
US6303819B1 (en) 2001-10-16
WO1999035123A1 (fr) 1999-07-15
ID26622A (id) 2001-01-25
EP1044186A1 (fr) 2000-10-18
DE69833797T2 (de) 2006-10-19
KR100629628B1 (ko) 2006-09-29

Similar Documents

Publication Publication Date Title
BG64700B1 (bg) Заместени 2-бензиламино-2-фенилацетамиди
KR100525587B1 (ko) 알파-아미노아미드 유도체 및 이를 포함하는 진통제용 약제학적 조성물
US4559337A (en) 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides
RU2424230C2 (ru) Соединения и способы ингибирования взаимодействия белков bcl с компонентами связывания
EA001322B1 (ru) Производные 2-(4-замещенного)-бензиламино-2-метилпропанамида
US5446066A (en) Substituted (arylalkoxybenzyl)aminopropanamide derivatives and process for their preparation
US5912242A (en) N-(4-substituted-benzyl)-2-aminolactam derivatives
KR20000048601A (ko) 니트론 유도체
DE3687035T2 (de) 3-aminopropyloxyphenylabkoemmlinge, herstellung und arzneitmittel die sie enthalten.
AU3959893A (en) N-aryloxy(thio)alkyl-azacycloalkanes useful as calcium channel antagonists
MXPA00006354A (en) Substituted 2-benzylamino-2-phenyl-acetamide compounds
US5093355A (en) Benzylpyrrolidine derivatives as dopamine agonists
JPH11180950A (ja) ヒドロキサム酸化合物
FR2827863A1 (fr) Derives d'aminoalkylimidazole, leur preparation et leur utilisation en therapeutique
MXPA00006352A (en) Alpha-aminoamide derivatives useful as analgesic agents