BG64621B1 - Метод за получаване на кетимин - Google Patents

Метод за получаване на кетимин Download PDF

Info

Publication number
BG64621B1
BG64621B1 BG104669A BG10466900A BG64621B1 BG 64621 B1 BG64621 B1 BG 64621B1 BG 104669 A BG104669 A BG 104669A BG 10466900 A BG10466900 A BG 10466900A BG 64621 B1 BG64621 B1 BG 64621B1
Authority
BG
Bulgaria
Prior art keywords
sertraline
solvent
mixture
monomethylamine
reaction
Prior art date
Application number
BG104669A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104669A (en
Inventor
Juan Colberg
David PFISTERED
Geraldine Taber
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22102365&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG64621(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG104669A publication Critical patent/BG104669A/xx
Publication of BG64621B1 publication Critical patent/BG64621B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
BG104669A 1998-01-16 2000-08-07 Метод за получаване на кетимин BG64621B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7160098P 1998-01-16 1998-01-16
PCT/IB1998/001619 WO1999036394A1 (en) 1998-01-16 1998-10-15 Novel process for preparing a ketimine

Publications (2)

Publication Number Publication Date
BG104669A BG104669A (en) 2001-04-30
BG64621B1 true BG64621B1 (bg) 2005-09-30

Family

ID=22102365

Family Applications (2)

Application Number Title Priority Date Filing Date
BG104669A BG64621B1 (bg) 1998-01-16 2000-08-07 Метод за получаване на кетимин
BG108878A BG64647B1 (bg) 1998-01-16 2000-08-07 Метод за получаване на сертралин

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG108878A BG64647B1 (bg) 1998-01-16 2000-08-07 Метод за получаване на сертралин

Country Status (48)

Country Link
US (1) US6232500B1 (xx)
EP (1) EP1047666B1 (xx)
JP (1) JP3533179B2 (xx)
KR (1) KR100362788B1 (xx)
CN (1) CN1121381C (xx)
AP (1) AP956A (xx)
AR (1) AR016168A1 (xx)
AT (1) ATE231121T1 (xx)
AU (1) AU747861B2 (xx)
BG (2) BG64621B1 (xx)
BR (1) BR9814248A (xx)
CA (1) CA2315761C (xx)
CO (1) CO5040154A1 (xx)
CZ (1) CZ20002594A3 (xx)
DE (1) DE69810815T2 (xx)
DK (1) DK1047666T3 (xx)
DZ (1) DZ2705A1 (xx)
EA (1) EA004952B1 (xx)
EG (1) EG21515A (xx)
ES (1) ES2186226T3 (xx)
GT (1) GT199800176A (xx)
HK (1) HK1032039A1 (xx)
HN (1) HN1998000167A (xx)
HR (1) HRP20000473A2 (xx)
HU (1) HUP0101253A3 (xx)
ID (1) ID24971A (xx)
IL (2) IL136888A0 (xx)
IN (1) IN191358B (xx)
IS (1) IS5538A (xx)
MA (1) MA24744A1 (xx)
MY (1) MY132956A (xx)
NO (1) NO20003625L (xx)
NZ (1) NZ505027A (xx)
OA (1) OA11439A (xx)
PA (1) PA8461901A1 (xx)
PE (1) PE20000171A1 (xx)
PL (1) PL192489B1 (xx)
PT (1) PT1047666E (xx)
RS (1) RS49773B (xx)
SI (1) SI1047666T1 (xx)
SK (1) SK10182000A3 (xx)
TN (1) TNSN99004A1 (xx)
TR (1) TR200002065T2 (xx)
TW (1) TW505624B (xx)
UA (1) UA55504C2 (xx)
UY (1) UY25348A1 (xx)
WO (1) WO1999036394A1 (xx)
ZA (1) ZA99278B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226423B1 (en) * 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing a 1(2h)-naphtalene-1-ylidene derivative
ATE272611T1 (de) * 1998-10-30 2004-08-15 Ciba Sc Holding Ag Verfahren zur herstellung von ketiminen
EP1637515A1 (en) * 1998-11-27 2006-03-22 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
IN185109B (xx) * 1999-09-01 2000-11-18 Torrent Pharmaceuticals Ltd
HUP0203384A3 (en) * 1999-11-16 2006-02-28 Ciba Sc Holding Ag Process for the preparation of ketimines
PT1230212E (pt) * 1999-11-16 2005-08-31 Ciba Sc Holding Ag Metodo de embalar elementos de construcao de brinquedo
IN187170B (xx) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
AU2001243634B2 (en) * 2000-03-14 2006-05-25 Teva Pharmaceutical Industries Ltd. Novel process for preparing (+)-cis-sertraline
CA2448300A1 (en) * 2001-05-31 2002-12-05 Orion Corporation Fermion Process for preparing sertraline intermediates
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
KR20030061474A (ko) * 2002-01-14 2003-07-22 한미약품 주식회사 서트랄린 제조용 중간체로서 사용되는 시스-라세메이트화합물의 개선된 제조방법
WO2006129324A2 (en) 2005-06-03 2006-12-07 Hetero Drugs Limited A highly stereoselective synthesis of sertraline

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226424B1 (en) 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing enantiomer mixture for preparation of sertraline

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine

Also Published As

Publication number Publication date
IN191358B (xx) 2003-11-29
IS5538A (is) 2000-06-16
HRP20000473A2 (en) 2001-04-30
DE69810815D1 (de) 2003-02-20
SK10182000A3 (sk) 2002-06-04
CA2315761A1 (en) 1999-07-22
SI1047666T1 (en) 2003-04-30
JP3533179B2 (ja) 2004-05-31
ZA99278B (en) 2000-07-17
AU9278698A (en) 1999-08-02
EP1047666B1 (en) 2003-01-15
AP9901441A0 (en) 1999-03-31
HUP0101253A3 (en) 2002-06-28
US6232500B1 (en) 2001-05-15
IL136888A (en) 2006-12-10
PE20000171A1 (es) 2000-03-09
MA24744A1 (fr) 1999-10-01
CZ20002594A3 (cs) 2001-12-12
KR100362788B1 (ko) 2002-11-29
KR20010034117A (ko) 2001-04-25
NO20003625L (no) 2000-09-13
NZ505027A (en) 2002-08-28
GT199800176A (es) 1998-11-09
CA2315761C (en) 2004-08-31
DE69810815T2 (de) 2003-08-07
PL192489B1 (pl) 2006-10-31
CN1285819A (zh) 2001-02-28
CN1121381C (zh) 2003-09-17
HN1998000167A (es) 1999-02-09
HK1032039A1 (en) 2001-07-06
PL341648A1 (en) 2001-04-23
EG21515A (en) 2001-11-28
CO5040154A1 (es) 2001-05-29
IL136888A0 (en) 2001-06-14
BG104669A (en) 2001-04-30
BR9814248A (pt) 2000-10-10
PT1047666E (pt) 2003-03-31
YU44300A (sh) 2002-09-19
EA200000661A1 (ru) 2000-12-25
HUP0101253A2 (hu) 2002-05-29
ES2186226T3 (es) 2003-05-01
WO1999036394A1 (en) 1999-07-22
EA004952B1 (ru) 2004-10-28
MY132956A (en) 2007-10-31
BG64647B1 (bg) 2005-10-31
ATE231121T1 (de) 2003-02-15
RS49773B (sr) 2008-06-05
AP956A (en) 2001-04-06
TNSN99004A1 (fr) 2005-11-10
EP1047666A1 (en) 2000-11-02
OA11439A (en) 2004-04-26
DZ2705A1 (fr) 2003-09-01
JP2002509132A (ja) 2002-03-26
ID24971A (id) 2000-08-31
TW505624B (en) 2002-10-11
NO20003625D0 (no) 2000-07-14
AR016168A1 (es) 2001-06-20
UA55504C2 (uk) 2003-04-15
TR200002065T2 (tr) 2000-11-21
DK1047666T3 (da) 2003-02-24
AU747861B2 (en) 2002-05-23
UY25348A1 (es) 1999-09-27
PA8461901A1 (es) 2000-05-24

Similar Documents

Publication Publication Date Title
EP2403823B1 (en) Process for the preparation of cinacalcet and salts thereof, and intermediates for use in the process
BG64621B1 (bg) Метод за получаване на кетимин
CH638185A5 (fr) Procede pour la preparation de 2,2,6,6-tetramethyl-4-piperidone.
RU2181358C2 (ru) Способ получения сертралина из хирального тетралона
US5877351A (en) Preparation and purification process for 2- (dimethylamino) methyl!-1-(3-methoxphenyl)-cyclohexanol and its salts
US6262308B1 (en) Process for the preparation of racemic sertraline
US6909017B2 (en) Method for isolating and purifying (1RS,2RS)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
EP1401800A1 (en) A novel process for the preparation of (is-cis) -4-(3, 4-dichlorophenyl) -1, 2, 3, 4 - tetrahydro-n-methyl-1-naphthalenamine
US6723878B2 (en) Method for preparing sertraline
MXPA00006986A (en) Novel process for preparing a ketimine
HU214840B (hu) Eljárás selegilin előállítására
CA2119052C (en) Enantioselective process for the preparation of levobunolol
EP1503978A1 (en) Process for the manufacture of sertraline
WO2012098044A1 (en) Process for the preparation of n,n-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate
DK174219B1 (da) Forbedret syntese af racemisk sertralin
EP3160937A1 (en) A novel method for synthesis of optically pure beta-amino alcohols
JPH10506380A (ja) Ｏ−（２−ヒドロキシアルキル）オキシムの製造方法
JPS5811420B2 (ja) ベンゾビシクロアルカンアミン類の製法