BG63392B1 - Производни на 5-нафтален-1-ил-1,3-диоксан, тяхното получаване и използването им като терапевтични средства - Google Patents

Производни на 5-нафтален-1-ил-1,3-диоксан, тяхното получаване и използването им като терапевтични средства Download PDF

Info

Publication number
BG63392B1
BG63392B1 BG102429A BG10242998A BG63392B1 BG 63392 B1 BG63392 B1 BG 63392B1 BG 102429 A BG102429 A BG 102429A BG 10242998 A BG10242998 A BG 10242998A BG 63392 B1 BG63392 B1 BG 63392B1
Authority
BG
Bulgaria
Prior art keywords
group
general formula
hydrogen atom
compounds
mmol
Prior art date
Application number
BG102429A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102429A (en
Inventor
Gihad Dargazanli
Yannick Evanno
Jonathan Frost
Patrick Lardenois
Mireille Sevrin
Pascal George
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of BG102429A publication Critical patent/BG102429A/xx
Publication of BG63392B1 publication Critical patent/BG63392B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG102429A 1995-12-06 1998-05-06 Производни на 5-нафтален-1-ил-1,3-диоксан, тяхното получаване и използването им като терапевтични средства BG63392B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514394A FR2742152B1 (fr) 1995-12-06 1995-12-06 Derives de 5-naphtalen-1-yl-1,3-dioxanes, leur preparation et leur application en therapeutique
PCT/FR1996/001926 WO1997020836A1 (fr) 1995-12-06 1996-12-04 Derives de 5-naphtalen-1-y1-1,3-dioxanes, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
BG102429A BG102429A (en) 1999-03-31
BG63392B1 true BG63392B1 (bg) 2001-12-29

Family

ID=9485181

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102429A BG63392B1 (bg) 1995-12-06 1998-05-06 Производни на 5-нафтален-1-ил-1,3-диоксан, тяхното получаване и използването им като терапевтични средства

Country Status (32)

Country Link
US (1) US5922739A (xx)
EP (1) EP0869952B1 (xx)
JP (1) JP2000501409A (xx)
KR (1) KR19990071965A (xx)
CN (1) CN1203597A (xx)
AR (1) AR004862A1 (xx)
AT (1) ATE205841T1 (xx)
AU (1) AU705747B2 (xx)
BG (1) BG63392B1 (xx)
BR (1) BR9611895A (xx)
CA (1) CA2236265A1 (xx)
CO (1) CO4750648A1 (xx)
CZ (1) CZ171798A3 (xx)
DE (1) DE69615396T2 (xx)
DK (1) DK0869952T3 (xx)
EE (1) EE03441B1 (xx)
ES (1) ES2163663T3 (xx)
FR (1) FR2742152B1 (xx)
HK (1) HK1016166A1 (xx)
HU (1) HUP9903696A3 (xx)
IL (1) IL124751A0 (xx)
NO (1) NO982549L (xx)
NZ (1) NZ323421A (xx)
PL (1) PL327059A1 (xx)
PT (1) PT869952E (xx)
RU (1) RU2163601C2 (xx)
SI (1) SI0869952T1 (xx)
SK (1) SK282451B6 (xx)
TR (1) TR199800838T2 (xx)
TW (1) TW498073B (xx)
WO (1) WO1997020836A1 (xx)
ZA (1) ZA9610251B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8025198A (en) * 1997-06-05 1998-12-21 Sanofi-Synthelabo 5-naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutic application
FR2843964B1 (fr) 2002-08-29 2004-10-01 Sanofi Synthelabo Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
CN1720490B (zh) 2002-11-15 2010-12-08 应用材料有限公司 用于控制具有多变量输入参数的制造工艺的方法和系统
KR102022116B1 (ko) 2011-06-24 2019-09-18 노노 인코포레이티드 허혈에 대한 psd-95 억제제와의 조합 요법
US9241970B2 (en) * 2011-12-13 2016-01-26 Nono Inc. Therapy for subarachnoid hemorrhage and ischemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0461958B1 (fr) * 1990-06-15 1994-09-14 Synthelabo Dérivés de 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxanes, leur préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
HUP9903696A3 (en) 2000-08-28
EP0869952A1 (fr) 1998-10-14
CO4750648A1 (es) 1999-03-31
JP2000501409A (ja) 2000-02-08
EP0869952B1 (fr) 2001-09-19
NO982549D0 (no) 1998-06-04
SI0869952T1 (en) 2002-02-28
HUP9903696A2 (en) 2000-07-28
AU1036097A (en) 1997-06-27
HK1016166A1 (en) 1999-10-29
IL124751A0 (en) 1999-01-26
ES2163663T3 (es) 2002-02-01
PL327059A1 (en) 1998-11-23
CA2236265A1 (en) 1997-06-12
NO982549L (no) 1998-08-06
AR004862A1 (es) 1999-03-10
RU2163601C2 (ru) 2001-02-27
DK0869952T3 (da) 2002-01-21
NZ323421A (en) 1998-10-28
CZ171798A3 (cs) 1998-09-16
SK282451B6 (sk) 2002-02-05
BG102429A (en) 1999-03-31
ATE205841T1 (de) 2001-10-15
KR19990071965A (ko) 1999-09-27
PT869952E (pt) 2002-02-28
CN1203597A (zh) 1998-12-30
FR2742152B1 (fr) 1998-01-16
ZA9610251B (en) 1997-06-23
AU705747B2 (en) 1999-06-03
WO1997020836A1 (fr) 1997-06-12
TW498073B (en) 2002-08-11
FR2742152A1 (fr) 1997-06-13
US5922739A (en) 1999-07-13
SK74498A3 (en) 1998-11-04
DE69615396T2 (de) 2002-06-13
TR199800838T2 (xx) 1998-09-21
EE9800153A (et) 1998-12-15
BR9611895A (pt) 1999-07-20
DE69615396D1 (de) 2001-10-25
EE03441B1 (et) 2001-06-15

Similar Documents

Publication Publication Date Title
ES2315851T3 (es) Derivados de imidazolina que tienen actividad antagonista cb1.
JP3560986B2 (ja) 5―ht2c受容体作用薬及びアミノアルキルインダゾール誘導体
RU2348620C2 (ru) Производные тиазола в качестве модуляторов каннабиноидного рецептора
CA2565293C (fr) Derives de tetrahydroisoquinolilsulfonamides, leur preparation et leur utilisation en therapeutique
NL8204279A (nl) Spyrocyclische verbinding.
BG65923B1 (bg) 2-оксо-1-пиролидинови производни, методи за тяхното получаване и приложенията им
EP0421762A1 (en) Novel nicotine analogs and method
UA81365C2 (en) Ccr-2 antagonist salt, method for modulation of chemokine receptor activity, method for treating (variants) and pharmaceutical composition
US6110947A (en) Pyrrolidinyl hydroxamic acid compounds and their production process
JP2024020453A (ja) Rock阻害剤としての重水素化合物
EP0233762B1 (en) Use of aromatic diamines for the treatment of angina pectoris, and diamines therefor
BG63392B1 (bg) Производни на 5-нафтален-1-ил-1,3-диоксан, тяхното получаване и използването им като терапевтични средства
ES2203090T3 (es) Procedimiento para la sintesis de inhibidores de proteasas del virus de la inmunodeficiencia humana.
ES2313358T3 (es) Derivados de imidazol tetrasustituidos como moduladores del receptor cannabinoide cb1 con una elevada selectividad de subtipo por el receptor cb1/cb2.
WO2023077049A1 (en) Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
DE3888811T2 (de) Tricyclische Carbamate, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung.
US3058986A (en) N-ammoalkyl-x-phenyl-x-lower alkyl-z-
EP0789021B1 (en) Hydroxamic acid compounds as opioid kappa receptor agonists
ES2285122T3 (es) Compuestos que poseen afinidad en los receptores de tipo 5ht1 y su uso en terapia de trastornos del snc.
JPS648620B2 (xx)
MXPA98004536A (en) Derivatives of 5-naftalen-1-il-1,3-dioxan, preparation and therapeutic use of mis
DE69211773T2 (de) Amidderivate von 1-Amino-Octahydropyrido[2,1-c][1,4]oxazin, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
SK166199A3 (en) 5-naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutic application
PT789021E (pt) Compostos de acido pirrolidinil hidroxamico e o processo para a sua producao
MXPA99011203A (en) 5-naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutic application