NO982549L - 5-naftalen-1-yl-1,3-dioksan-derivater, fremstilling og terapeutisk anvendelse derav - Google Patents

5-naftalen-1-yl-1,3-dioksan-derivater, fremstilling og terapeutisk anvendelse derav

Info

Publication number
NO982549L
NO982549L NO982549A NO982549A NO982549L NO 982549 L NO982549 L NO 982549L NO 982549 A NO982549 A NO 982549A NO 982549 A NO982549 A NO 982549A NO 982549 L NO982549 L NO 982549L
Authority
NO
Norway
Prior art keywords
group
therapeutic use
phenyl
naphthalen
preparation
Prior art date
Application number
NO982549A
Other languages
English (en)
Other versions
NO982549D0 (no
Inventor
Gihad Dargazanli
Yannick Evanno
Jonathan Frost
Patrick Lardenois
Mireille Sevrin
Pascal George
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO982549D0 publication Critical patent/NO982549D0/no
Publication of NO982549L publication Critical patent/NO982549L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Forbindelse-med generell formel (I) hvor R^ er et hydrogen- atom eller en (C1-C4) alkyl, (C3-C6) cykloalkylmetyl eller fenyl (C1-C3) alkylgruppe, eventuelt substituert, på fenyl- ringen, med en eller flere atomer eller grupper valgt fra halogenér og gruppene metyl, trifluormetyl, metoksy og cyano, R2 er en hydroksy- eller alkoksygruppe eller en gruppe med generell -formel NR3R4 hvor hver av R3 og R4 er et hydrogen- atom, en alkylgruppe, en cykoalkylgruppe, en cykloalkyl- metylgruppe, en fenylgruppe, en fenylmetylgruppe eller en pyridinylgruppe, eller R3 og R4 danner sammen med nitrogen- atomet en pyrrolidin- eller piperidinring, og n er l, 2 eller 3. Forbindelsene er egnet for terapeutisk anvendelse.
NO982549A 1995-12-06 1998-06-04 5-naftalen-1-yl-1,3-dioksan-derivater, fremstilling og terapeutisk anvendelse derav NO982549L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514394A FR2742152B1 (fr) 1995-12-06 1995-12-06 Derives de 5-naphtalen-1-yl-1,3-dioxanes, leur preparation et leur application en therapeutique
PCT/FR1996/001926 WO1997020836A1 (fr) 1995-12-06 1996-12-04 Derives de 5-naphtalen-1-y1-1,3-dioxanes, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
NO982549D0 NO982549D0 (no) 1998-06-04
NO982549L true NO982549L (no) 1998-08-06

Family

ID=9485181

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982549A NO982549L (no) 1995-12-06 1998-06-04 5-naftalen-1-yl-1,3-dioksan-derivater, fremstilling og terapeutisk anvendelse derav

Country Status (32)

Country Link
US (1) US5922739A (no)
EP (1) EP0869952B1 (no)
JP (1) JP2000501409A (no)
KR (1) KR19990071965A (no)
CN (1) CN1203597A (no)
AR (1) AR004862A1 (no)
AT (1) ATE205841T1 (no)
AU (1) AU705747B2 (no)
BG (1) BG63392B1 (no)
BR (1) BR9611895A (no)
CA (1) CA2236265A1 (no)
CO (1) CO4750648A1 (no)
CZ (1) CZ171798A3 (no)
DE (1) DE69615396T2 (no)
DK (1) DK0869952T3 (no)
EE (1) EE03441B1 (no)
ES (1) ES2163663T3 (no)
FR (1) FR2742152B1 (no)
HK (1) HK1016166A1 (no)
HU (1) HUP9903696A3 (no)
IL (1) IL124751A0 (no)
NO (1) NO982549L (no)
NZ (1) NZ323421A (no)
PL (1) PL327059A1 (no)
PT (1) PT869952E (no)
RU (1) RU2163601C2 (no)
SI (1) SI0869952T1 (no)
SK (1) SK282451B6 (no)
TR (1) TR199800838T2 (no)
TW (1) TW498073B (no)
WO (1) WO1997020836A1 (no)
ZA (1) ZA9610251B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8025198A (en) * 1997-06-05 1998-12-21 Sanofi-Synthelabo 5-naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutic application
FR2843964B1 (fr) * 2002-08-29 2004-10-01 Sanofi Synthelabo Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
WO2004046835A2 (en) 2002-11-15 2004-06-03 Applied Materials, Inc. Method, system and medium for controlling manufacture process having multivariate input parameters
PT2723363T (pt) 2011-06-24 2018-11-08 Nono Inc Terapia de combinação para isquemia
US9241970B2 (en) 2011-12-13 2016-01-26 Nono Inc. Therapy for subarachnoid hemorrhage and ischemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2064057T3 (es) * 1990-06-15 1995-01-16 Synthelabo Unos derivados de 2-(aminoalquil)-5-(arilalquil)-1,3-dioxanos, su preparacion y su aplicacion en terapeutica.

Also Published As

Publication number Publication date
BG63392B1 (bg) 2001-12-29
EP0869952A1 (fr) 1998-10-14
RU2163601C2 (ru) 2001-02-27
EE03441B1 (et) 2001-06-15
SI0869952T1 (en) 2002-02-28
PT869952E (pt) 2002-02-28
FR2742152A1 (fr) 1997-06-13
ATE205841T1 (de) 2001-10-15
PL327059A1 (en) 1998-11-23
AU1036097A (en) 1997-06-27
HUP9903696A2 (en) 2000-07-28
TW498073B (en) 2002-08-11
AR004862A1 (es) 1999-03-10
HUP9903696A3 (en) 2000-08-28
DE69615396D1 (de) 2001-10-25
NO982549D0 (no) 1998-06-04
ES2163663T3 (es) 2002-02-01
DK0869952T3 (da) 2002-01-21
SK282451B6 (sk) 2002-02-05
CZ171798A3 (cs) 1998-09-16
ZA9610251B (en) 1997-06-23
US5922739A (en) 1999-07-13
WO1997020836A1 (fr) 1997-06-12
SK74498A3 (en) 1998-11-04
DE69615396T2 (de) 2002-06-13
IL124751A0 (en) 1999-01-26
KR19990071965A (ko) 1999-09-27
NZ323421A (en) 1998-10-28
BG102429A (en) 1999-03-31
EP0869952B1 (fr) 2001-09-19
CN1203597A (zh) 1998-12-30
JP2000501409A (ja) 2000-02-08
BR9611895A (pt) 1999-07-20
HK1016166A1 (en) 1999-10-29
EE9800153A (et) 1998-12-15
TR199800838T2 (xx) 1998-09-21
CO4750648A1 (es) 1999-03-31
AU705747B2 (en) 1999-06-03
CA2236265A1 (en) 1997-06-12
FR2742152B1 (fr) 1998-01-16

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FC2A Withdrawal, rejection or dismissal of laid open patent application