NO943236L - Nye 1,2-ditiol-3-tionderivater og farmasöytisk preparat inneholdende disse - Google Patents
Nye 1,2-ditiol-3-tionderivater og farmasöytisk preparat inneholdende disseInfo
- Publication number
- NO943236L NO943236L NO943236A NO943236A NO943236L NO 943236 L NO943236 L NO 943236L NO 943236 A NO943236 A NO 943236A NO 943236 A NO943236 A NO 943236A NO 943236 L NO943236 L NO 943236L
- Authority
- NO
- Norway
- Prior art keywords
- group
- integer
- dithiol
- independently
- alkyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Nye, terapeutisk virksomme l,2-ditiol-3- tion-derivater med de generelle formler (1) og (11): R1 ^f^ (CH,). S HO, S d) hvor A er en metylengruppe eller et ok- sygenatom; R1 og R2 uavhengig av hveran- dre er et hydrogenatom, en hydroksyl- gruppe, et halogenatom, en lavere alkyl- gruppe eller en lavere alkoksygruppe; og n er et helt tall fra O til 3 når A er en metylengruppe, og et helt tall fra l til 3 når A er et oksygenatom; S03H (11) S¿S hvor k er et helt tall fra O til 5, X og Y uavhengig av hverandre er et hydrogen- atom, en lavere alkylgruppe eller en lavere alkoksygruppe, R11 er en alkyl- gruppe eller en gruppe representert ved den generelle formel: R12 hvor m er et helt tall fra O til 4, og R12, R13 og R" uavhengig av hverandre er et hydrogenatom, en lavere alkylgruppe eller en lavere alkoksygruppe, med unn- tak av det tilfelle hvor både k og n er O, sulfogruppen er bundet i 3-stillin- gen, X er en 4-metoksygruppe og hver av R12, R13 og R14 er hydrogen; og salter av disse forbindelser med formler (1) og (11). Det beskrives også et terapeutisk eller forebyggende middel for sykdommer forbundet med peroksyli- pid, inneholdende som aktiv bestanddel en av de nye forbindelser.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5218482A JPH0770109A (ja) | 1993-09-02 | 1993-09-02 | 過酸化脂質が関与する疾患の治療剤および予防剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO943236D0 NO943236D0 (no) | 1994-09-01 |
| NO943236L true NO943236L (no) | 1995-03-03 |
Family
ID=16720623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO943236A NO943236L (no) | 1993-09-02 | 1994-09-01 | Nye 1,2-ditiol-3-tionderivater og farmasöytisk preparat inneholdende disse |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0641792A1 (no) |
| JP (1) | JPH0770109A (no) |
| KR (1) | KR950008514A (no) |
| CN (1) | CN1106013A (no) |
| CA (1) | CA2131074A1 (no) |
| FI (1) | FI943989A (no) |
| NO (1) | NO943236L (no) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001009118A2 (en) * | 1999-07-29 | 2001-02-08 | Patrick T Prendergast | Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement |
| CN101429190B (zh) * | 2007-08-24 | 2013-03-27 | 沈阳药科大学 | 4,5-二取代苯基-3h-1,2-二硫杂环戊烯-3-硫酮、-酮、-酮肟类衍生物及其用途 |
| CN112961086B (zh) * | 2021-02-05 | 2022-10-21 | 齐鲁工业大学 | 一种2-亚甲基-1-茚酮衍生物及其合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1526768A (fr) * | 1963-01-16 | 1968-05-31 | Procédé de préparation de dérivés sulfoniques de dithiole-1, 2 thiones-3 diversement substituées, et applications des produits ainsi obtenus | |
| JPH05301868A (ja) * | 1992-04-23 | 1993-11-16 | Mitsui Toatsu Chem Inc | 虚血性心疾患治療剤 |
-
1993
- 1993-09-02 JP JP5218482A patent/JPH0770109A/ja active Pending
-
1994
- 1994-08-29 CA CA002131074A patent/CA2131074A1/en not_active Abandoned
- 1994-08-31 KR KR1019940021834A patent/KR950008514A/ko active IP Right Grant
- 1994-08-31 FI FI943989A patent/FI943989A/fi not_active Application Discontinuation
- 1994-09-01 NO NO943236A patent/NO943236L/no unknown
- 1994-09-02 CN CN94113711A patent/CN1106013A/zh active Pending
- 1994-09-02 EP EP94113804A patent/EP0641792A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NO943236D0 (no) | 1994-09-01 |
| FI943989A0 (fi) | 1994-08-31 |
| JPH0770109A (ja) | 1995-03-14 |
| CA2131074A1 (en) | 1995-03-03 |
| KR950008514A (ko) | 1995-04-17 |
| CN1106013A (zh) | 1995-08-02 |
| EP0641792A1 (en) | 1995-03-08 |
| FI943989A (fi) | 1995-03-03 |
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