ATE8633T1 - Vinyl-3-cephalosporinverbindungen und ihre herstellung. - Google Patents
Vinyl-3-cephalosporinverbindungen und ihre herstellung.Info
- Publication number
- ATE8633T1 ATE8633T1 AT81401823T AT81401823T ATE8633T1 AT E8633 T1 ATE8633 T1 AT E8633T1 AT 81401823 T AT81401823 T AT 81401823T AT 81401823 T AT81401823 T AT 81401823T AT E8633 T1 ATE8633 T1 AT E8633T1
- Authority
- AT
- Austria
- Prior art keywords
- radical
- bicyclooct
- ene
- amino
- alkyl
- Prior art date
Links
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8024634A FR2494275A2 (fr) | 1980-11-20 | 1980-11-20 | Nouveaux derives de vinyl-3 cephalosporines et leur preparation |
EP81401823A EP0053537B1 (de) | 1980-11-20 | 1981-11-19 | Vinyl-3-Cephalosporinverbindungen und ihre Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE8633T1 true ATE8633T1 (de) | 1984-08-15 |
Family
ID=9248168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT81401823T ATE8633T1 (de) | 1980-11-20 | 1981-11-19 | Vinyl-3-cephalosporinverbindungen und ihre herstellung. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4423214A (de) |
EP (1) | EP0053537B1 (de) |
JP (1) | JPS57114593A (de) |
AT (1) | ATE8633T1 (de) |
DE (1) | DE3165118D1 (de) |
FR (1) | FR2494275A2 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4486586A (en) * | 1983-02-10 | 1984-12-04 | Bristol-Myers Company | Cephalosporin derivatives |
US4874856A (en) * | 1985-06-24 | 1989-10-17 | Bristol-Myers Company | 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof |
US4708955A (en) * | 1985-06-24 | 1987-11-24 | Bristol-Myers Company | 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof |
KR100342600B1 (ko) * | 2000-03-06 | 2002-07-04 | 한미정밀화학주식회사 | 신규한 티아졸 화합물 및 그의 제조 방법 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3769277A (en) * | 1970-01-23 | 1973-10-30 | Glaxo Lab Ltd | Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group |
GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
US4065620A (en) * | 1971-06-14 | 1977-12-27 | Eli Lilly And Company | 3-(Substituted) vinyl cephalosporins |
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
FR2457296A1 (fr) * | 1979-05-23 | 1980-12-19 | Rhone Poulenc Ind | Nouveaux derives de vinyl-3 cephalosporines et leur preparation |
-
1980
- 1980-11-20 FR FR8024634A patent/FR2494275A2/fr active Granted
-
1981
- 1981-11-19 AT AT81401823T patent/ATE8633T1/de not_active IP Right Cessation
- 1981-11-19 DE DE8181401823T patent/DE3165118D1/de not_active Expired
- 1981-11-19 US US06/322,949 patent/US4423214A/en not_active Expired - Fee Related
- 1981-11-19 EP EP81401823A patent/EP0053537B1/de not_active Expired
- 1981-11-20 JP JP56185560A patent/JPS57114593A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS57114593A (en) | 1982-07-16 |
DE3165118D1 (en) | 1984-08-30 |
US4423214A (en) | 1983-12-27 |
EP0053537B1 (de) | 1984-07-25 |
FR2494275A2 (fr) | 1982-05-21 |
JPH0345078B2 (de) | 1991-07-09 |
FR2494275B2 (de) | 1983-04-15 |
EP0053537A1 (de) | 1982-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |