ES520526A0 - Procedimiento para la obtencion de derivados de piridina. - Google Patents
Procedimiento para la obtencion de derivados de piridina.Info
- Publication number
- ES520526A0 ES520526A0 ES520526A ES520526A ES520526A0 ES 520526 A0 ES520526 A0 ES 520526A0 ES 520526 A ES520526 A ES 520526A ES 520526 A ES520526 A ES 520526A ES 520526 A0 ES520526 A0 ES 520526A0
- Authority
- ES
- Spain
- Prior art keywords
- radical
- procedure
- obtaining
- patient
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823209276 DE3209276A1 (de) | 1982-03-13 | 1982-03-13 | Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8401321A1 ES8401321A1 (es) | 1983-12-16 |
ES520526A0 true ES520526A0 (es) | 1983-12-16 |
Family
ID=6158230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES520526A Granted ES520526A0 (es) | 1982-03-13 | 1983-03-11 | Procedimiento para la obtencion de derivados de piridina. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4497821A (es) |
EP (1) | EP0088938B1 (es) |
JP (1) | JPS58167570A (es) |
AT (1) | ATE19514T1 (es) |
DE (2) | DE3209276A1 (es) |
ES (1) | ES520526A0 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3209274A1 (de) * | 1982-03-13 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Pyridincarbonsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
JPS58185821U (ja) * | 1982-06-02 | 1983-12-10 | 日産自動車株式会社 | ウインドシ−ルド |
DE3410645A1 (de) * | 1984-03-23 | 1985-09-26 | Bayer Ag, 5090 Leverkusen | L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
DE3424342A1 (de) * | 1984-07-03 | 1986-01-09 | Bayer Ag, 5090 Leverkusen | 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridin-3,5-dicarbonsaeure-isopropyl-(2-(3-trifluormethylphenoxy)-ethyl)-ester, mehrere verfahren zu seiner herstellung sowie seine verwendung in arzneimitteln |
FR2568773B1 (fr) * | 1984-08-10 | 1989-03-03 | Sandoz Lab | Nouvelles compositions pharmaceutiques administrables par voie nasale |
US4659717A (en) * | 1985-08-21 | 1987-04-21 | Eli Lilly And Company | Dihydropyridines useful in the treatment of angina and stroke |
US4990507A (en) * | 1985-12-12 | 1991-02-05 | Fujisawa Pharmaceutical Co., Ltd. | N-containing heterocyclic compounds, and composition comprising the same |
GB8530602D0 (en) * | 1985-12-12 | 1986-01-22 | Fujisawa Pharmaceutical Co | Heterocyclic compounds |
CA1312611C (en) * | 1987-07-01 | 1993-01-12 | Yamanouchi Pharmaceutical Co., Ltd. | Pyridine derivatives, process for production thereof and pharmaceutical composition containing them |
GB8905526D0 (en) * | 1989-03-10 | 1989-04-19 | Fujisawa Pharmaceutical Co | N-containing heterocyclic compounds,processes for the preparation thereof and composition comprising the same |
PT657432E (pt) | 1993-12-10 | 2003-07-31 | Bayer Ag | 1,4-di-hidropiridinas fenil-substituidas com actividade cerebral |
DE4430639A1 (de) | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
CH692199A8 (fr) * | 1997-10-09 | 2002-06-14 | Cermol S.A. | Composes pyridiques et compositions pharmaceutique |
US20050203119A1 (en) * | 2003-09-10 | 2005-09-15 | Mitsunori Ono | Dihydropyridine compounds for treating or preventing metabolic disorders |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1440647A (fr) * | 1963-12-10 | 1966-06-03 | Ciba Geigy | Nouveaux agents pesticides |
US3907808A (en) * | 1971-05-17 | 1975-09-23 | Sterling Drug Inc | 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives |
US3922278A (en) * | 1972-06-12 | 1975-11-25 | Sterling Drug Inc | 4-(3-Nitrophenyl)-3,5-pyridinedicarboxylic acid |
GB1552911A (en) * | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
DE3023820A1 (de) * | 1980-06-25 | 1982-01-14 | Bayer Ag, 5090 Leverkusen | 4,4-disubstituierte spiro-1,4-dihydropyridine, ein verfahren zu ihrer herstellung, sowie ihre verwendung als zwischenprodukt |
-
1982
- 1982-03-13 DE DE19823209276 patent/DE3209276A1/de not_active Withdrawn
-
1983
- 1983-02-28 US US06/470,883 patent/US4497821A/en not_active Expired - Fee Related
- 1983-03-02 EP EP83101999A patent/EP0088938B1/de not_active Expired
- 1983-03-02 DE DE8383101999T patent/DE3363248D1/de not_active Expired
- 1983-03-02 AT AT83101999T patent/ATE19514T1/de not_active IP Right Cessation
- 1983-03-11 JP JP58039302A patent/JPS58167570A/ja active Pending
- 1983-03-11 ES ES520526A patent/ES520526A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
ATE19514T1 (de) | 1986-05-15 |
ES8401321A1 (es) | 1983-12-16 |
EP0088938A1 (de) | 1983-09-21 |
DE3363248D1 (en) | 1986-06-05 |
EP0088938B1 (de) | 1986-04-30 |
DE3209276A1 (de) | 1983-09-15 |
US4497821A (en) | 1985-02-05 |
JPS58167570A (ja) | 1983-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19960603 |