BG62773B1 - Имидазопиридини и тяхното приложение за лечение на стомашно-чревни заболявания - Google Patents

Имидазопиридини и тяхното приложение за лечение на стомашно-чревни заболявания Download PDF

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Publication number
BG62773B1
BG62773B1 BG99855A BG9985595A BG62773B1 BG 62773 B1 BG62773 B1 BG 62773B1 BG 99855 A BG99855 A BG 99855A BG 9985595 A BG9985595 A BG 9985595A BG 62773 B1 BG62773 B1 BG 62773B1
Authority
BG
Bulgaria
Prior art keywords
compounds
formula
pyridine
methylbenzylamino
dimethylimidazo
Prior art date
Application number
BG99855A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG99855A (bg
Inventor
Stefan Postius
Richard Riedel
Wolfgang-Alexander Simon
Joerg Senn-Bilfinger
Gerhard Grundler
Georg Reiner
Original Assignee
Byk Gulden Lomberg Chemische Fabrik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh
Publication of BG99855A publication Critical patent/BG99855A/bg
Publication of BG62773B1 publication Critical patent/BG62773B1/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG99855A 1993-02-15 1995-08-09 Имидазопиридини и тяхното приложение за лечение на стомашно-чревни заболявания BG62773B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH45393 1993-02-15
CH194593 1993-06-29
PCT/EP1994/000335 WO1994018199A1 (de) 1993-02-15 1994-02-07 Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten

Publications (2)

Publication Number Publication Date
BG99855A BG99855A (bg) 1996-04-30
BG62773B1 true BG62773B1 (bg) 2000-07-31

Family

ID=25684624

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99855A BG62773B1 (bg) 1993-02-15 1995-08-09 Имидазопиридини и тяхното приложение за лечение на стомашно-чревни заболявания

Country Status (29)

Country Link
US (1) US5665730A (pl)
EP (1) EP0683780B1 (pl)
JP (1) JP3447292B2 (pl)
KR (1) KR100297057B1 (pl)
CN (1) CN1052005C (pl)
AT (1) ATE192151T1 (pl)
AU (1) AU678434B2 (pl)
BG (1) BG62773B1 (pl)
CA (1) CA2156078C (pl)
CZ (1) CZ287313B6 (pl)
DE (1) DE59409312D1 (pl)
DK (1) DK0683780T3 (pl)
ES (1) ES2148317T3 (pl)
FI (1) FI109537B (pl)
GR (1) GR3033846T3 (pl)
HU (1) HU219395B (pl)
IL (1) IL108520A (pl)
MY (1) MY111201A (pl)
NO (1) NO304889B1 (pl)
NZ (1) NZ261579A (pl)
PL (1) PL175932B1 (pl)
PT (1) PT683780E (pl)
RO (1) RO117917B1 (pl)
RU (1) RU2136682C1 (pl)
SG (1) SG55184A1 (pl)
SK (1) SK280822B6 (pl)
TW (1) TW293008B (pl)
UA (1) UA43841C2 (pl)
WO (1) WO1994018199A1 (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69524598T2 (de) * 1994-06-20 2002-07-11 Takeda Chemical Industries, Ltd. Kondensierte imidazolderivate, ihre herstellung und verwendung
JPH10505331A (ja) * 1994-07-28 1998-05-26 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンジルイミダゾピリジン
EP0773946B1 (de) * 1994-07-28 2002-03-27 Byk Gulden Lomberg Chemische Fabrik GmbH Imidazopyridin-azolidinone
WO1996005199A1 (de) * 1994-08-12 1996-02-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazopyridinsalz
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
JP2949474B2 (ja) * 1995-08-28 1999-09-13 隆久 古田 ペプシノーゲンi/ii比の変化率を基礎としたヘリコバクター・ピロリ除菌判定方法
DE19602855A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue 3-Methylimidazopyridine
CA2244770A1 (en) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chemische Fabrik Gmbh 3-methylimidazopyridines
AU1545297A (en) * 1996-01-26 1997-08-20 Byk Gulden Imidazopyridine halides
PT971922E (pt) 1997-03-24 2004-09-30 Altana Pharma Ag Compostos de tetra-hidropirido
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
DK1173439T3 (da) 1999-04-17 2003-09-08 Altana Pharma Ag Halogenalkoxy-imidazonaphthyridiner
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6780880B1 (en) * 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
DE10145457A1 (de) 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2493618A1 (en) * 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0204785A1 (de) * 1984-12-14 1986-12-17 Ulrich Möbius Halterung für skier
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
SG55184A1 (en) 1998-12-21
BG99855A (bg) 1996-04-30
FI953838A0 (fi) 1995-08-14
RU2136682C1 (ru) 1999-09-10
PL310171A1 (en) 1995-11-27
AU6039194A (en) 1994-08-29
CN1052005C (zh) 2000-05-03
IL108520A (en) 1997-09-30
EP0683780B1 (de) 2000-04-26
HUT72436A (en) 1996-04-29
WO1994018199A1 (de) 1994-08-18
HU219395B (hu) 2001-04-28
KR100297057B1 (ko) 2001-10-24
CZ287313B6 (en) 2000-10-11
TW293008B (pl) 1996-12-11
CA2156078C (en) 2005-02-01
DE59409312D1 (de) 2000-05-31
NZ261579A (en) 1997-03-24
RO117917B1 (ro) 2002-09-30
CZ208895A3 (en) 1995-12-13
US5665730A (en) 1997-09-09
JPH08506333A (ja) 1996-07-09
GR3033846T3 (en) 2000-10-31
UA43841C2 (uk) 2002-01-15
MY111201A (en) 1999-09-30
ES2148317T3 (es) 2000-10-16
SK280822B6 (sk) 2000-08-14
KR960701051A (ko) 1996-02-24
NO304889B1 (no) 1999-03-01
AU678434B2 (en) 1997-05-29
FI109537B (fi) 2002-08-30
CN1119863A (zh) 1996-04-03
SK99795A3 (en) 1995-12-06
CA2156078A1 (en) 1994-08-18
ATE192151T1 (de) 2000-05-15
PT683780E (pt) 2000-10-31
NO953187L (no) 1995-08-14
IL108520A0 (en) 1994-05-30
PL175932B1 (pl) 1999-03-31
EP0683780A1 (de) 1995-11-29
JP3447292B2 (ja) 2003-09-16
DK0683780T3 (da) 2000-09-25
NO953187D0 (no) 1995-08-14
FI953838A (fi) 1995-09-06

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