BG61477B1 - Peptides of organoprotective activity, method for their preparation and their therapeutical use - Google Patents

Peptides of organoprotective activity, method for their preparation and their therapeutical use Download PDF

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Publication number
BG61477B1
BG61477B1 BG98426A BG9842694A BG61477B1 BG 61477 B1 BG61477 B1 BG 61477B1 BG 98426 A BG98426 A BG 98426A BG 9842694 A BG9842694 A BG 9842694A BG 61477 B1 BG61477 B1 BG 61477B1
Authority
BG
Bulgaria
Prior art keywords
pro
peptide
gly
seq
leu
Prior art date
Application number
BG98426A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG98426A (bg
Inventor
Predrag Sikiric
Marijan Petek
Sven Seiwerth
Zeljko Grabarevic
Ivo Rotkvic
Marko Duvnjak
Branko Turkovic
Stjepan Mise
Ernest Suchanek
Boris Mildner
Ivan Udovicic
Original Assignee
Predrag Sikiric
Marijan Petek
Sven Seiwerth
Zeljko Grabarevic
Ivo Rotkvic
Marko Duvnjak
Branko Turkovic
Stjepan Mise
Ernest Suchanek
Boris Mildner
Ivan Udovicic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Predrag Sikiric, Marijan Petek, Sven Seiwerth, Zeljko Grabarevic, Ivo Rotkvic, Marko Duvnjak, Branko Turkovic, Stjepan Mise, Ernest Suchanek, Boris Mildner, Ivan Udovicic filed Critical Predrag Sikiric
Publication of BG98426A publication Critical patent/BG98426A/bg
Publication of BG61477B1 publication Critical patent/BG61477B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BG98426A 1992-05-30 1994-01-28 Peptides of organoprotective activity, method for their preparation and their therapeutical use BG61477B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92109145A EP0572688B1 (en) 1992-05-30 1992-05-30 Peptides with organo-protective activity, the process for preparing them and their use in therapy
PCT/EP1993/001352 WO1993024521A1 (en) 1992-05-30 1993-05-28 Bpc peptides, their preparation and use

Publications (2)

Publication Number Publication Date
BG98426A BG98426A (bg) 1995-02-28
BG61477B1 true BG61477B1 (en) 1997-09-30

Family

ID=8209663

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98426A BG61477B1 (en) 1992-05-30 1994-01-28 Peptides of organoprotective activity, method for their preparation and their therapeutical use

Country Status (23)

Country Link
US (2) US6211151B1 (no)
EP (2) EP0572688B1 (no)
JP (1) JP2783681B2 (no)
KR (1) KR0180256B1 (no)
AT (2) ATE152734T1 (no)
AU (1) AU4319693A (no)
BG (1) BG61477B1 (no)
CA (1) CA2114313C (no)
CZ (1) CZ284972B6 (no)
DE (2) DE69219590T2 (no)
DK (2) DK0572688T3 (no)
ES (2) ES2103854T3 (no)
FI (1) FI120454B (no)
GR (2) GR3024379T3 (no)
HK (1) HK1001004A1 (no)
HU (1) HU224073B1 (no)
NO (1) NO310027B1 (no)
PL (1) PL176208B1 (no)
RO (1) RO112506B1 (no)
RU (1) RU2111214C1 (no)
SK (1) SK278507B6 (no)
UA (1) UA32523C2 (no)
WO (1) WO1993024521A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69219590T2 (de) 1992-05-30 1997-11-27 Marko Duvnjak BPC-Peptide, deren Herstellung und Verwendung
DE69316974T2 (de) * 1992-11-16 1998-07-16 Marko Zagreb Duvnjak Bpc-peptide, deren herstellung und therapeutischen verwendung
UA61955C2 (en) * 1997-05-23 2003-12-15 Novel salts of bpc-peptides with organoprojective activity, a process for preparing and use thereof in therapy
US6844315B2 (en) 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
US8680059B2 (en) 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
EP1138692A1 (en) 2000-03-29 2001-10-04 Erasmus Universiteit Rotterdam Fragments of human chorionic gonadotropin (hcg) as immunoregulator
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
EP1300418A1 (en) * 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Gene regulation by oligopeptides
US7358330B2 (en) 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
USRE43279E1 (en) 2000-03-29 2012-03-27 Biotemp B.V. Compositions capable of reducing elevated blood urea concentration
US7786084B2 (en) * 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
US7517529B2 (en) * 2003-04-08 2009-04-14 Biotempt B.V. Treatment of type I diabetes
US20090227505A1 (en) * 2004-01-07 2009-09-10 Biotempt B.V. Methods and uses for protein breakdown products
WO2007004869A2 (en) 2005-07-05 2007-01-11 Biotempt B.V. Treatment of tumors
EP1864692A1 (en) * 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
CN101443080B (zh) * 2006-03-07 2015-01-14 比奥滕普特公司 肽在控制辐射损伤中的用途
NZ578956A (en) * 2007-02-12 2012-02-24 Biotempt Bv Treatment of trauma hemorrhage with short oligopeptides
SI24318A (sl) 2013-03-13 2014-09-30 Diagen D.O.O. Nove stabilne soli pentadekapeptida, postopek za njihovo pripravo, njihova uporaba za izdelavo farmacevtskih pripravkov in njihova uporaba v terapiji
CN113683663A (zh) * 2021-09-16 2021-11-23 杭州信海医药科技有限公司 一种机体保护多肽粗品的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717300D0 (en) * 1987-07-22 1987-08-26 Nat Res Dev Cyclosporins
CA1337781C (en) * 1987-08-21 1995-12-19 Takanori Nakamura Polypeptide from horseshoe crab exhibiting affinity for lipopolysaccharide and method of preparation
YU176089A (sh) * 1989-09-12 1992-09-07 Sikirić, Predrag Postupak za pripremu supstancije bpc i supstancija bpc
DE69219590T2 (de) 1992-05-30 1997-11-27 Marko Duvnjak BPC-Peptide, deren Herstellung und Verwendung

Also Published As

Publication number Publication date
FI940375A (fi) 1994-01-26
RO112506B1 (ro) 1997-10-30
ATE155485T1 (de) 1997-08-15
DK0601154T3 (da) 1998-02-23
EP0572688A1 (en) 1993-12-08
NO940299L (no) 1994-01-28
UA32523C2 (uk) 2001-02-15
HK1001004A1 (en) 1998-05-15
CZ20594A3 (en) 1994-12-15
EP0601154B1 (en) 1997-07-16
DE69219590T2 (de) 1997-11-27
ES2103854T3 (es) 1997-10-01
DK0572688T3 (da) 1997-12-01
DE69312232T2 (de) 1998-01-29
FI120454B (fi) 2009-10-30
ES2107033T3 (es) 1997-11-16
CZ284972B6 (cs) 1999-04-14
KR0180256B1 (en) 1999-04-01
SK278507B6 (en) 1997-08-06
NO310027B1 (no) 2001-05-07
CA2114313A1 (en) 1993-12-09
GR3024905T3 (en) 1998-01-30
CA2114313C (en) 2003-01-14
BG98426A (bg) 1995-02-28
HU9400252D0 (en) 1994-05-30
PL176208B1 (pl) 1999-04-30
US6268346B1 (en) 2001-07-31
ATE152734T1 (de) 1997-05-15
AU4319693A (en) 1993-12-30
RU2111214C1 (ru) 1998-05-20
JP2783681B2 (ja) 1998-08-06
NO940299D0 (no) 1994-01-28
HU224073B1 (hu) 2005-05-30
DE69219590D1 (de) 1997-06-12
EP0601154A1 (en) 1994-06-15
US6211151B1 (en) 2001-04-03
HUT66309A (en) 1994-11-28
FI940375A0 (fi) 1994-01-26
SK9694A3 (en) 1994-08-10
WO1993024521A1 (en) 1993-12-09
EP0572688B1 (en) 1997-05-07
PL302304A1 (en) 1994-07-25
JPH06509588A (ja) 1994-10-27
GR3024379T3 (en) 1997-11-28
DE69312232D1 (de) 1997-08-21

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