BG60434B2 - Теофилинилалкилоксадиазоли,метод за получаванетоим и фармацевтични състави,които ги съдържат - Google Patents

Теофилинилалкилоксадиазоли,метод за получаванетоим и фармацевтични състави,които ги съдържат Download PDF

Info

Publication number
BG60434B2
BG60434B2 BG98262A BG9826293A BG60434B2 BG 60434 B2 BG60434 B2 BG 60434B2 BG 98262 A BG98262 A BG 98262A BG 9826293 A BG9826293 A BG 9826293A BG 60434 B2 BG60434 B2 BG 60434B2
Authority
BG
Bulgaria
Prior art keywords
theophylline
oxadiazol
methyl
ethan
formula
Prior art date
Application number
BG98262A
Other languages
Bulgarian (bg)
English (en)
Inventor
Dezsoe Korbonits
Geb. Wundele Maria Szomor
Gergely Heja
Geb. Kanzel Ida Szvoboda
Pal Kiss
Csaba Goenczi
Endre Palosi
Gabor Kovacs
Judit Kun
Emil Minker
Sandor Virag
Gyula Sebestyen
Tamas Szuets
Original Assignee
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. filed Critical Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
Publication of BG60434B2 publication Critical patent/BG60434B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG98262A 1982-03-12 1993-12-02 Теофилинилалкилоксадиазоли,метод за получаванетоим и фармацевтични състави,които ги съдържат BG60434B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU82762A HU190377B (en) 1982-03-12 1982-03-12 Process for preparing theophyllinyl-alkyl-oxadiazoles

Publications (1)

Publication Number Publication Date
BG60434B2 true BG60434B2 (bg) 1995-03-31

Family

ID=10951220

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98262A BG60434B2 (bg) 1982-03-12 1993-12-02 Теофилинилалкилоксадиазоли,метод за получаванетоим и фармацевтични състави,които ги съдържат

Country Status (17)

Country Link
US (1) US4565817A (da)
EP (1) EP0089028B1 (da)
JP (1) JPS5910586A (da)
AT (1) ATE34575T1 (da)
BG (1) BG60434B2 (da)
DD (1) DD207377A5 (da)
DE (1) DE3376749D1 (da)
DK (1) DK161385C (da)
ES (2) ES8504195A1 (da)
FI (1) FI72320C (da)
GR (1) GR78450B (da)
HU (1) HU190377B (da)
IL (1) IL68093A0 (da)
NO (1) NO159794C (da)
PL (2) PL138857B1 (da)
SK (1) SK170183A3 (da)
SU (3) SU1322981A3 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles
LV5262A3 (lv) * 1986-10-09 1993-10-10 Chinoin Gyogyszer Es Vegyeszet Oksadiazolilalkilpurina atvasinajumi kam piemit pretklepus aktivitate
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances
HU198933B (en) * 1987-11-02 1989-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
HU206884B (en) * 1990-11-22 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing purin derivatives and pharmaceutical compositions containing them
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
US5340813A (en) * 1992-11-09 1994-08-23 Cell Therapeutics, Inc. Substituted aminoalkyl xanthine compounds
AU6087894A (en) * 1993-01-14 1994-08-15 Cell Therapeutics, Inc. Acetal or ketal substituted therapeutic compounds
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds
US20070215201A1 (en) * 2006-03-17 2007-09-20 Lawrence Curtin Photovoltaic cell with integral light transmitting waveguide in a ceramic sleeve
CA2691468C (en) * 2007-06-22 2017-05-09 Hydra Biosciences, Inc. Substituted xanthine compounds and methods to treat diseases mediated by trpa1
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1063323B (de) * 1957-06-29 1959-08-13 Willi Keil Zentrifugalgeblaese oder -pumpe
GB1053825A (da) * 1963-03-22
DE1620576A1 (de) * 1966-11-25 1970-02-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von Theophyllin- und Theobrominverbindungen
DE1670497C3 (de) * 1967-06-06 1973-12-20 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest Isochinohnderivate und Verfahren zu deren Herstellung
IT1156913B (it) * 1978-03-13 1987-02-04 Geymonat Sud Spa Composto ad attivita farmaceutica e procedimento per la sua preparazione
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
IT1195267B (it) * 1980-04-15 1988-10-12 Abc Ist Biolog Chem Spa Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles

Also Published As

Publication number Publication date
FI830831L (fi) 1983-09-13
DK161385C (da) 1991-12-16
SK278001B6 (en) 1995-09-13
JPH0532395B2 (da) 1993-05-14
DD207377A5 (de) 1984-02-29
PL138550B1 (en) 1986-10-31
NO159794C (no) 1989-02-08
PL240990A1 (en) 1985-01-02
HU190377B (en) 1986-08-28
SU1297729A3 (ru) 1987-03-15
FI72320B (fi) 1987-01-30
GR78450B (da) 1984-09-27
DE3376749T2 (da) 1988-06-30
SU1322981A3 (ru) 1987-07-07
EP0089028B1 (de) 1988-05-25
EP0089028A1 (de) 1983-09-21
JPS5910586A (ja) 1984-01-20
DK118083A (da) 1983-09-13
ES534146A0 (es) 1985-07-01
PL249225A1 (en) 1985-06-04
PL138857B1 (en) 1986-11-29
FI72320C (fi) 1987-05-11
NO830843L (no) 1983-09-13
ES520860A0 (es) 1985-04-16
US4565817A (en) 1986-01-21
DE3376749D1 (en) 1988-06-30
FI830831A0 (fi) 1983-03-11
DK118083D0 (da) 1983-03-11
SK170183A3 (en) 1995-09-13
SU1344756A1 (ru) 1987-10-15
DK161385B (da) 1991-07-01
NO159794B (no) 1988-10-31
ATE34575T1 (de) 1988-06-15
IL68093A0 (en) 1983-06-15
ES8505999A1 (es) 1985-07-01
ES8504195A1 (es) 1985-04-16

Similar Documents

Publication Publication Date Title
EP1720864B1 (en) Benzimidazol substituted thiophene derivatives with activity on ikk3
US7534800B2 (en) 7-azaindoles as inhibitors of c-Jun N-terminal kinases for the treatment of neurodegenerative disorders
BG60434B2 (bg) Теофилинилалкилоксадиазоли,метод за получаванетоим и фармацевтични състави,които ги съдържат
US5225409A (en) Benzoxazinone compounds
US5614518A (en) Morpholine derivatives as dopamine receptor subtype ligands
US6964960B2 (en) Indoloquinazolinones
RU2007404C1 (ru) Способ получения производных оксадиазолалкилпурина или их фармацевтически приемлемых кислотно-аддитивных солей (его варианты)
JP2010501533A (ja) Ｍ３レセプター調節物質として有用な窒素含有複素環化合物
US20120214812A1 (en) Compounds and compositions as lxr modulators
EP0568437B1 (en) Antidepressant 3-Halophenylpiperazinyl-propyl Derivatives of Substituted Triazolones and Triazoldiones
DK162219B (da) 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner
CS262417B2 (en) Process for preparing new 1h,3h-pyrrolo/1,2-c/-thiazoles
CS259516B2 (en) Method of new heterocyclic compounds production
EP0386722A1 (en) Imidazoquinolone derivatives
FI82247C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara imidazo (1,2-a) pyrimidiner och salter av daerav.
SU793397A3 (ru) Способ получени производных пиперазина или их солей
WO1997002254A1 (en) Quinazoline derivatives
EP0133259A2 (en) Aminoalkyl-substituted benzene derivatives, process for production thereof, and pharmaceutical composition thereof
JPH0227345B2 (da)
CZ282155B6 (cs) Nové theofylinové deriváty, substituované v poloze -7 a způsob jejich výroby i použití
JPH03264585A (ja) イミダゾキノロン誘導体
JPH05262770A (ja) 化学的製法
JP2004075563A (ja) 放射線増感剤
CS201042B2 (cs) Způsob výroby etherifikovaných hydroxybenzodiheterocyklických sloučenin