BG27902A3 - Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes - Google Patents

Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes

Info

Publication number
BG27902A3
BG27902A3 BG028037A BG2803774A BG27902A3 BG 27902 A3 BG27902 A3 BG 27902A3 BG 028037 A BG028037 A BG 028037A BG 2803774 A BG2803774 A BG 2803774A BG 27902 A3 BG27902 A3 BG 27902A3
Authority
BG
Bulgaria
Prior art keywords
morphinanes
benzomorphanes
furilmethil
methoxy
methyl
Prior art date
Application number
BG028037A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Longbein
Gerhard Walter
Klaus Stokhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG27902A3 publication Critical patent/BG27902A3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG028037A 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes BG27902A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BG27902A3 true BG27902A3 (en) 1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028038A BG27903A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid
BG028037A BG27902A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028038A BG27903A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Country Status (27)

Country Link
US (1) US3981874A (ru)
JP (1) JPS5738590B2 (ru)
AT (6) AT335634B (ru)
BE (1) BE821505A (ru)
BG (3) BG27901A3 (ru)
CA (1) CA1056377A (ru)
CH (6) CH609046A5 (ru)
CS (3) CS171195B2 (ru)
DD (1) DD115909A5 (ru)
DE (1) DE2354002A1 (ru)
DK (1) DK138325C (ru)
ES (6) ES431056A1 (ru)
FI (1) FI62079C (ru)
FR (1) FR2248838B1 (ru)
GB (1) GB1482552A (ru)
HU (1) HU176479B (ru)
IE (1) IE41528B1 (ru)
IL (1) IL45938A (ru)
NL (1) NL7413980A (ru)
NO (1) NO140859C (ru)
PH (1) PH11894A (ru)
PL (3) PL92053B1 (ru)
RO (5) RO65656A (ru)
SE (1) SE422791B (ru)
SU (6) SU511005A3 (ru)
YU (5) YU36519B (ru)
ZA (1) ZA746790B (ru)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
JP5769970B2 (ja) * 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2711757C (en) * 2008-02-12 2016-07-26 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
JP5379160B2 (ja) 2008-07-25 2013-12-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
JP5777030B2 (ja) 2008-07-25 2015-09-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es) * 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166802B2 (ru) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
IL45938A (en) 1977-12-30
RO65656A (ro) 1980-06-15
RO65658A (fr) 1979-07-15
DE2354002A1 (de) 1975-05-07
PH11894A (en) 1978-08-29
AT335634B (de) 1977-03-25
FI314174A (ru) 1975-04-28
CS171194B2 (ru) 1976-10-29
SU508192A3 (ru) 1976-03-25
FI62079C (fi) 1982-11-10
YU285274A (en) 1982-02-25
BG27901A3 (bg) 1980-01-15
YU285474A (en) 1982-06-18
SU511005A3 (ru) 1976-04-15
RO65659A (ro) 1980-06-15
YU36950B (en) 1984-08-31
CS171195B2 (ru) 1976-10-29
YU285374A (en) 1982-06-18
ATA828974A (de) 1976-08-15
CA1056377A (en) 1979-06-12
CH609046A5 (ru) 1979-02-15
RO65655A (ro) 1980-06-15
RO65657A (ro) 1980-06-15
IE41528L (en) 1975-04-27
PL92086B1 (ru) 1977-03-31
ATA828574A (de) 1976-07-15
IL45938A0 (en) 1974-12-31
CH609340A5 (ru) 1979-02-28
YU36519B (en) 1984-02-29
SE7413485L (ru) 1975-04-28
FR2248838A1 (ru) 1975-05-23
SU510999A3 (ru) 1976-04-15
DK138325B (da) 1978-08-14
NO140859B (no) 1979-08-20
BE821505A (fr) 1975-04-25
ATA828674A (de) 1976-07-15
PL92052B1 (ru) 1977-03-31
BG27903A3 (en) 1980-01-15
FR2248838B1 (ru) 1977-11-04
DK559874A (ru) 1975-06-23
NO743845L (ru) 1975-05-26
IE41528B1 (en) 1980-01-30
CH609686A5 (ru) 1979-03-15
PL92053B1 (ru) 1977-03-31
JPS5738590B2 (ru) 1982-08-16
US3981874A (en) 1976-09-21
YU285674A (en) 1982-06-18
SU578870A3 (ru) 1977-10-30
ATA829074A (de) 1976-07-15
CH609047A5 (ru) 1979-02-15
ZA746790B (en) 1976-06-30
ES431056A1 (es) 1976-10-16
ES431059A1 (es) 1976-10-16
YU36952B (en) 1984-08-31
DD115909A5 (ru) 1975-10-20
AT335632B (de) 1977-03-25
NO140859C (no) 1979-11-28
ATA828774A (de) 1976-07-15
CH609048A5 (ru) 1979-02-15
ES431055A1 (es) 1976-10-16
YU36949B (en) 1984-08-31
FI62079B (fi) 1982-07-30
AT335076B (de) 1977-02-25
ES431057A1 (es) 1976-10-16
ES431054A1 (es) 1976-10-16
AT336202B (de) 1977-04-25
CH609685A5 (ru) 1979-03-15
NL7413980A (nl) 1975-04-29
JPS5071679A (ru) 1975-06-13
AT335631B (de) 1977-03-25
ES431058A1 (es) 1976-10-16
GB1482552A (en) 1977-08-10
HU176479B (en) 1981-03-28
SU512707A3 (ru) 1976-04-30
YU285174A (en) 1982-06-18
YU36951B (en) 1984-08-31
SE422791B (sv) 1982-03-29
DK138325C (da) 1979-01-22
CS171196B2 (ru) 1976-10-29
ATA828874A (de) 1976-06-15
AT335633B (de) 1977-03-25
SU508193A3 (ru) 1976-03-25

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