BG25087A3 - Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли - Google Patents

Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли

Info

Publication number
BG25087A3
BG25087A3 BG029183A BG2918375A BG25087A3 BG 25087 A3 BG25087 A3 BG 25087A3 BG 029183 A BG029183 A BG 029183A BG 2918375 A BG2918375 A BG 2918375A BG 25087 A3 BG25087 A3 BG 25087A3
Authority
BG
Bulgaria
Prior art keywords
tetrahydrophupphupyl
benzomorphanes
salts
preparation
Prior art date
Application number
BG029183A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG25087A3 publication Critical patent/BG25087A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG029183A 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли BG25087A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
BG25087A3 true BG25087A3 (bg) 1978-07-12

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли
BG030537A BG24813A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG030537A BG24813A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Country Status (25)

Country Link
JP (1) JPS5827275B2 (OSRAM)
AT (1) AT344332B (OSRAM)
BE (1) BE826440A (OSRAM)
BG (3) BG25087A3 (OSRAM)
CA (1) CA1049511A (OSRAM)
CH (8) CH612425A5 (OSRAM)
CS (1) CS188221B2 (OSRAM)
DD (1) DD119236A5 (OSRAM)
DE (1) DE2411382C3 (OSRAM)
DK (1) DK137188C (OSRAM)
ES (6) ES440347A1 (OSRAM)
FI (1) FI63571C (OSRAM)
FR (1) FR2262984B1 (OSRAM)
GB (1) GB1496418A (OSRAM)
HU (1) HU177408B (OSRAM)
IE (1) IE40945B1 (OSRAM)
IL (1) IL46760A (OSRAM)
NL (1) NL7502724A (OSRAM)
NO (1) NO141800C (OSRAM)
PH (1) PH14127A (OSRAM)
PL (3) PL93699B1 (OSRAM)
RO (2) RO69617A (OSRAM)
SE (1) SE421919B (OSRAM)
SU (3) SU577982A3 (OSRAM)
ZA (1) ZA751394B (OSRAM)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
US8329897B2 (en) 2007-07-26 2012-12-11 Vitae Pharmaceuticals, Inc. Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1
CA2704628C (en) 2007-11-16 2016-11-29 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
PL2300461T3 (pl) 2008-05-01 2013-09-30 Vitae Pharmaceuticals Inc Cykliczne inhibitory dehydrogenazy 11beta-hydroksysteroidów 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5379160B2 (ja) 2008-07-25 2013-12-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
JP5656986B2 (ja) 2009-06-11 2015-01-21 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
ES440349A1 (es) 1977-03-01
PL93700B1 (OSRAM) 1977-06-30
ES440348A1 (es) 1977-06-01
NO750773L (OSRAM) 1975-09-10
SU577982A3 (ru) 1977-10-25
FI63571C (fi) 1983-07-11
BG24813A4 (bg) 1978-05-12
PH14127A (en) 1981-02-26
ES440350A1 (es) 1977-03-16
SU577983A3 (ru) 1977-10-25
NO141800B (no) 1980-02-04
SE7502592L (OSRAM) 1975-09-10
PL93499B1 (OSRAM) 1977-05-30
DD119236A5 (OSRAM) 1976-04-12
CH620440A5 (en) 1980-11-28
RO69617A (ro) 1980-08-15
CH622015A5 (en) 1981-03-13
NO141800C (no) 1980-06-04
ES440346A1 (es) 1977-03-01
NL7502724A (nl) 1975-09-11
SE421919B (sv) 1982-02-08
DE2411382C3 (de) 1979-09-06
CH612425A5 (en) 1979-07-31
CA1049511A (en) 1979-02-27
IE40945L (en) 1975-09-09
PL93699B1 (OSRAM) 1977-06-30
DK137188C (da) 1978-07-03
DE2411382B2 (de) 1979-01-18
AU7894275A (en) 1976-09-16
FR2262984B1 (OSRAM) 1978-07-28
JPS5827275B2 (ja) 1983-06-08
AT344332B (de) 1978-07-10
CH622014A5 (en) 1981-03-13
IE40945B1 (en) 1979-09-12
ES440345A1 (es) 1977-03-01
CH620681A5 (en) 1980-12-15
CH622016A5 (en) 1981-03-13
DE2411382A1 (de) 1975-09-18
FI750652A7 (OSRAM) 1975-09-10
FR2262984A1 (OSRAM) 1975-10-03
ZA751394B (en) 1976-11-24
CS188221B2 (en) 1979-02-28
HU177408B (en) 1981-10-28
RO70051A (ro) 1980-12-30
IL46760A (en) 1978-12-17
CH622017A5 (en) 1981-03-13
FI63571B (fi) 1983-03-31
JPS50123675A (OSRAM) 1975-09-29
IL46760A0 (en) 1975-05-22
DK92975A (OSRAM) 1975-09-10
GB1496418A (en) 1977-12-30
ATA153875A (de) 1977-11-15
CH620439A5 (en) 1980-11-28
DK137188B (da) 1978-01-30
ES440347A1 (es) 1977-06-01
BG24814A4 (bg) 1978-05-12
SU588916A3 (ru) 1978-01-15
BE826440A (fr) 1975-09-08

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