ZA751394B - Novel benzomorphanes,possessing analgesic effects - Google Patents

Novel benzomorphanes,possessing analgesic effects

Info

Publication number
ZA751394B
ZA751394B ZA751394A ZA751394A ZA751394B ZA 751394 B ZA751394 B ZA 751394B ZA 751394 A ZA751394 A ZA 751394A ZA 751394 A ZA751394 A ZA 751394A ZA 751394 B ZA751394 B ZA 751394B
Authority
ZA
South Africa
Prior art keywords
benzomorphanes
novel
analgesic effects
possessing analgesic
possessing
Prior art date
Application number
ZA751394A
Other languages
English (en)
Inventor
Herberg Merz
Merz Herberg
Adolf Langbein
Langbein Adolf
Gerhard Walther
Walther Gerhard
Klaus Stockhaus
Stockhaus Klaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ZA751394B publication Critical patent/ZA751394B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA751394A 1974-03-09 1975-03-07 Novel benzomorphanes,possessing analgesic effects ZA751394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
ZA751394B true ZA751394B (en) 1976-11-24

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA751394A ZA751394B (en) 1974-03-09 1975-03-07 Novel benzomorphanes,possessing analgesic effects

Country Status (25)

Country Link
JP (1) JPS5827275B2 (OSRAM)
AT (1) AT344332B (OSRAM)
BE (1) BE826440A (OSRAM)
BG (3) BG25087A3 (OSRAM)
CA (1) CA1049511A (OSRAM)
CH (8) CH612425A5 (OSRAM)
CS (1) CS188221B2 (OSRAM)
DD (1) DD119236A5 (OSRAM)
DE (1) DE2411382C3 (OSRAM)
DK (1) DK137188C (OSRAM)
ES (6) ES440349A1 (OSRAM)
FI (1) FI63571C (OSRAM)
FR (1) FR2262984B1 (OSRAM)
GB (1) GB1496418A (OSRAM)
HU (1) HU177408B (OSRAM)
IE (1) IE40945B1 (OSRAM)
IL (1) IL46760A (OSRAM)
NL (1) NL7502724A (OSRAM)
NO (1) NO141800C (OSRAM)
PH (1) PH14127A (OSRAM)
PL (3) PL93499B1 (OSRAM)
RO (2) RO70051A (OSRAM)
SE (1) SE421919B (OSRAM)
SU (3) SU577982A3 (OSRAM)
ZA (1) ZA751394B (OSRAM)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
HU225148B1 (en) * 1995-03-10 2006-07-28 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy or diagnosis, products and kits comprising thereof and method of in vitro diagnosis by their using
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
AR067673A1 (es) 2007-07-26 2009-10-21 Vitae Pharmaceuticals Inc Derivados de 1,3 oxazinan - 2 - ona como inhibidores ciclicos de la 11 beta -hidroxiesteroide deshidrogenasa 1. composiciones farmaceuticas.
AR069545A1 (es) 2007-11-16 2010-02-03 Boehringer Ingelheim Pharma Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター
WO2009102460A2 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MX2010011935A (es) 2008-05-01 2011-05-19 Vitae Pharmaceuticals Inc Inhibidores ciclicos de 11 beta-hidroxiesteroide deshidrogenasa 1.
JP5711115B2 (ja) 2008-05-13 2015-04-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリサイクリックカルボン酸誘導体、そのような化合物を含有する医薬及びその使用
NZ590495A (en) 2008-07-25 2012-10-26 Vitae Pharmaceuticals Inc Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜芳基羰基衍生物
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
EP2744783A1 (en) 2011-08-17 2014-06-25 Boehringer Ingelheim International GmbH Indenopyridine derivatives

Also Published As

Publication number Publication date
DK137188C (da) 1978-07-03
ES440347A1 (es) 1977-06-01
IE40945L (en) 1975-09-09
AT344332B (de) 1978-07-10
FI63571B (fi) 1983-03-31
DK137188B (da) 1978-01-30
FI750652A7 (OSRAM) 1975-09-10
ATA153875A (de) 1977-11-15
NO141800B (no) 1980-02-04
RO70051A (ro) 1980-12-30
ES440348A1 (es) 1977-06-01
ES440349A1 (es) 1977-03-01
DE2411382A1 (de) 1975-09-18
PL93499B1 (OSRAM) 1977-05-30
SE421919B (sv) 1982-02-08
NO141800C (no) 1980-06-04
ES440345A1 (es) 1977-03-01
BG24813A4 (bg) 1978-05-12
JPS5827275B2 (ja) 1983-06-08
DK92975A (OSRAM) 1975-09-10
SU577983A3 (ru) 1977-10-25
DD119236A5 (OSRAM) 1976-04-12
FR2262984B1 (OSRAM) 1978-07-28
FR2262984A1 (OSRAM) 1975-10-03
PL93700B1 (OSRAM) 1977-06-30
BG24814A4 (bg) 1978-05-12
CA1049511A (en) 1979-02-27
NO750773L (OSRAM) 1975-09-10
GB1496418A (en) 1977-12-30
CS188221B2 (en) 1979-02-28
CH622014A5 (en) 1981-03-13
FI63571C (fi) 1983-07-11
DE2411382B2 (de) 1979-01-18
ES440350A1 (es) 1977-03-16
PH14127A (en) 1981-02-26
BE826440A (fr) 1975-09-08
CH620681A5 (en) 1980-12-15
SU577982A3 (ru) 1977-10-25
IE40945B1 (en) 1979-09-12
NL7502724A (nl) 1975-09-11
PL93699B1 (OSRAM) 1977-06-30
IL46760A0 (en) 1975-05-22
CH622016A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
HU177408B (en) 1981-10-28
ES440346A1 (es) 1977-03-01
RO69617A (ro) 1980-08-15
SU588916A3 (ru) 1978-01-15
DE2411382C3 (de) 1979-09-06
BG25087A3 (bg) 1978-07-12
IL46760A (en) 1978-12-17
JPS50123675A (OSRAM) 1975-09-29
CH620439A5 (en) 1980-11-28
SE7502592L (OSRAM) 1975-09-10
CH612425A5 (en) 1979-07-31
AU7894275A (en) 1976-09-16
CH620440A5 (en) 1980-11-28
CH622015A5 (en) 1981-03-13

Similar Documents

Publication Publication Date Title
ZA751394B (en) Novel benzomorphanes,possessing analgesic effects
JPS51102636A (en) Karaashashingazo no keiseihoho
JPS5113709A (en) Echiren no ensokajudotai no seizoho
HK56980A (en) 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
ZA754630B (en) 2-thiol-4,5-diphenyloxazole s-derivatives
CA1029374A (en) 2-substituted-5,6-dimethoxyindazoles
JPS5119744A (en) Koseibutsushitsu xkk6222 no shinkyudotainoseiho
JPS5183225A (en) Ben mataha soretodoshunomononotameno ichihyojiki
JPS511268A (en) Kokurui no atsupenkakohoho
JPS511668A (en) Komekojojinzomai no seizoho
JPS5113474A (en) Kendakueki no zoryubunrisochi
JPS511666A (en) Kakokokuruifunmatsu no seizoho
GB1516534A (en) Basically substituted 3,4-dihydro-2h-isoquinolin-1-thione
JPS511661A (en) Kaatsukyoseitairyu nyoru kokurui no tankijoshahoho
IL47487A0 (en) 9-thia-or oxothia-and dioxothia-11,12-seco-prostaglandins
JPS5115105A (en) Judoki no kyusokukatsuteisonshitsunasuitsuchinguyokairo
JPS50105675A (en) Pirajinjudotai no seiho
JPS511664A (en) Patsukuiryudemen no seizoho
JPS511554A (en) Senjohoriesuteru no seizoho
JPS5120271A (en) Taidenboshipaipu no seikeihoho
JPS51102976A (en) Biniiruhausu no kankisochi
PH13535A (en) Cyclohexa-2,5-diene-1-thiones
JPS514277A (en) As jushifunmatsuofukumu ekinoshoriho
JPS5115668A (en) Kansonikurui mataha kansoyasairui no seizoho
JPS5113104A (en) Shoberurooda no baketsutojidosuiheifutsukisochi