BG20596A3 - Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини - Google Patents
Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазиниInfo
- Publication number
- BG20596A3 BG20596A3 BG026972A BG2697273A BG20596A3 BG 20596 A3 BG20596 A3 BG 20596A3 BG 026972 A BG026972 A BG 026972A BG 2697273 A BG2697273 A BG 2697273A BG 20596 A3 BG20596 A3 BG 20596A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- piperazines
- benzhydryl
- hydroxybenzyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2226767A DE2226767A1 (de) | 1972-06-02 | 1972-06-02 | N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung |
| DE19732312212 DE2312212A1 (de) | 1973-03-12 | 1973-03-12 | N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG20596A3 true BG20596A3 (bg) | 1975-12-05 |
Family
ID=25763357
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG023741A BG20595A3 (bg) | 1972-06-02 | 1973-05-29 | Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини |
| BG026973A BG20371A3 (bg) | 1972-06-02 | 1973-05-29 | Метод за получаване на n-бензхидрил-n'-р- хидробензил-пиперазини |
| BG026972A BG20596A3 (bg) | 1972-06-02 | 1973-05-29 | Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG023741A BG20595A3 (bg) | 1972-06-02 | 1973-05-29 | Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини |
| BG026973A BG20371A3 (bg) | 1972-06-02 | 1973-05-29 | Метод за получаване на n-бензхидрил-n'-р- хидробензил-пиперазини |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US3868377A (hu) |
| JP (1) | JPS4948687A (hu) |
| AR (5) | AR194688A1 (hu) |
| AT (3) | AT331252B (hu) |
| AU (1) | AU470393B2 (hu) |
| BG (3) | BG20595A3 (hu) |
| CA (1) | CA980347A (hu) |
| CH (4) | CH593959A5 (hu) |
| CS (4) | CS178430B2 (hu) |
| DD (1) | DD106644A5 (hu) |
| DK (1) | DK139751C (hu) |
| EG (1) | EG11434A (hu) |
| ES (3) | ES415465A1 (hu) |
| FI (1) | FI55656C (hu) |
| FR (1) | FR2186265B1 (hu) |
| GB (1) | GB1386916A (hu) |
| HU (1) | HU165312B (hu) |
| IE (1) | IE37717B1 (hu) |
| IL (1) | IL42384A (hu) |
| NL (1) | NL7306771A (hu) |
| NO (1) | NO138026C (hu) |
| PH (1) | PH9485A (hu) |
| PL (3) | PL91050B1 (hu) |
| RO (3) | RO68378A (hu) |
| SE (1) | SE396385B (hu) |
| SU (4) | SU508196A3 (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59101475A (ja) * | 1982-12-02 | 1984-06-12 | Nippon Chemiphar Co Ltd | 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤 |
| HU186656B (en) * | 1982-12-28 | 1985-09-30 | Richter Gedeon Vegyeszet | Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them |
| GB8320701D0 (en) * | 1983-08-01 | 1983-09-01 | Wellcome Found | Chemotherapeutic agent |
| JPS60222472A (ja) * | 1984-03-30 | 1985-11-07 | Kanebo Ltd | 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物 |
| AU617631B2 (en) * | 1988-08-05 | 1991-11-28 | Nippon Chemiphar Co. Ltd. | Optically active piperazine derivative |
| FR2661176B1 (fr) * | 1990-04-20 | 1992-06-12 | Adir | Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive. |
| ATE199716T1 (de) * | 1993-12-08 | 2001-03-15 | Alcon Lab Inc | Verbindungen die sowohl starke calcium- antagonistische und antioxydatieve aktivitaet haben und deren verwendung als zellschuetzende mittel. |
| CN102046612A (zh) * | 2008-06-02 | 2011-05-04 | 希普拉有限公司 | 合成左旋西替利嗪的方法和其中所用的中间体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2709169A (en) * | 1955-05-24 | X c chs | ||
| US3051710A (en) * | 1959-12-21 | 1962-08-28 | Lakeside Lab Inc | Glycolic acid amide derivatives of piperazine and use thereof |
-
1973
- 1973-05-15 NL NL7306771A patent/NL7306771A/xx not_active Application Discontinuation
- 1973-05-28 IE IE855/73A patent/IE37717B1/xx unknown
- 1973-05-29 BG BG023741A patent/BG20595A3/xx unknown
- 1973-05-29 CS CS3878A patent/CS178430B2/cs unknown
- 1973-05-29 RO RO7382539A patent/RO68378A/ro unknown
- 1973-05-29 US US364764A patent/US3868377A/en not_active Expired - Lifetime
- 1973-05-29 CS CS7600004284A patent/CS182248B2/cs unknown
- 1973-05-29 CS CS7300003883A patent/CS182234B2/cs unknown
- 1973-05-29 RO RO7382540A patent/RO68379A/ro unknown
- 1973-05-29 BG BG026973A patent/BG20371A3/xx unknown
- 1973-05-29 IL IL42384A patent/IL42384A/en unknown
- 1973-05-29 BG BG026972A patent/BG20596A3/xx unknown
- 1973-05-29 CS CS3877A patent/CS178429B2/cs unknown
- 1973-05-29 RO RO7374944A patent/RO62900A/ro unknown
- 1973-05-30 GB GB2571073A patent/GB1386916A/en not_active Expired
- 1973-05-30 SE SE7307692A patent/SE396385B/xx unknown
- 1973-05-31 AU AU56343/73A patent/AU470393B2/en not_active Expired
- 1973-05-31 PH PH14678*UA patent/PH9485A/en unknown
- 1973-05-31 CA CA172,824A patent/CA980347A/en not_active Expired
- 1973-05-31 DD DD171224A patent/DD106644A5/xx unknown
- 1973-05-31 PL PL1973162986A patent/PL91050B1/pl unknown
- 1973-05-31 AR AR248326A patent/AR194688A1/es active
- 1973-05-31 SU SU1926943A patent/SU508196A3/ru active
- 1973-05-31 AR AR248325A patent/AR196936A1/es active
- 1973-05-31 PL PL1973186639A patent/PL94759B1/pl unknown
- 1973-05-31 PL PL1973186638A patent/PL97129B1/pl unknown
- 1973-05-31 SU SU1926942A patent/SU530644A3/ru active
- 1973-05-31 AR AR248327A patent/AR201001A1/es active
- 1973-05-31 SU SU1926939A patent/SU507238A3/ru active
- 1973-05-31 HU HUCA347A patent/HU165312B/hu unknown
- 1973-05-31 JP JP48060375A patent/JPS4948687A/ja active Pending
- 1973-05-31 EG EG206/73A patent/EG11434A/xx active
- 1973-06-01 AT AT483273A patent/AT331252B/de not_active IP Right Cessation
- 1973-06-01 FI FI1797/73A patent/FI55656C/fi active
- 1973-06-01 ES ES73415465A patent/ES415465A1/es not_active Expired
- 1973-06-01 NO NO2303/73A patent/NO138026C/no unknown
- 1973-06-01 DK DK304673A patent/DK139751C/da active
- 1973-06-01 AT AT483173A patent/AT331802B/de not_active IP Right Cessation
- 1973-06-01 ES ES415466A patent/ES415466A1/es not_active Expired
- 1973-06-01 FR FR7319998A patent/FR2186265B1/fr not_active Expired
- 1973-06-01 ES ES415464A patent/ES415464A1/es not_active Expired
- 1973-06-01 AT AT483073A patent/AT331801B/de not_active IP Right Cessation
- 1973-06-04 CH CH803073A patent/CH593959A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH802973A patent/CH579064A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH1193576A patent/CH594651A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH802873A patent/CH574949A5/xx not_active IP Right Cessation
-
1974
- 1974-01-01 AR AR252417A patent/AR204987A1/es active
- 1974-02-18 AR AR252416A patent/AR200764A1/es active
- 1974-12-13 SU SU7402082532A patent/SU577995A3/ru active
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