BG108874A - Isostructural pseudo-polymorphs of 9-deoxo-9a-aza-methyl-9a-homoerythromycin - Google Patents

Isostructural pseudo-polymorphs of 9-deoxo-9a-aza-methyl-9a-homoerythromycin

Info

Publication number
BG108874A
BG108874A BG108874A BG10887404A BG108874A BG 108874 A BG108874 A BG 108874A BG 108874 A BG108874 A BG 108874A BG 10887404 A BG10887404 A BG 10887404A BG 108874 A BG108874 A BG 108874A
Authority
BG
Bulgaria
Prior art keywords
deoxo
aza
methyl
homoerythromycin
isostructural
Prior art date
Application number
BG108874A
Other languages
Bulgarian (bg)
English (en)
Inventor
Miljenko Dumic
Mladen Vinkovic
Marina Oresic
Ernest Mestrovic
Aleksandar Danilovski
Alojz Dumbovic
Zdravka Knezevic
Gorjana Lazarevski
Dominic Cincic
Darko Filic
Katica Lazaric
Dejan-Kresimir Bucar
Original Assignee
Pliva-Istrazivacki Institut D.O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istrazivacki Institut D.O.O. filed Critical Pliva-Istrazivacki Institut D.O.O.
Publication of BG108874A publication Critical patent/BG108874A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Finger-Pressure Massage (AREA)
  • Instructional Devices (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG108874A 2002-03-18 2004-09-14 Isostructural pseudo-polymorphs of 9-deoxo-9a-aza-methyl-9a-homoerythromycin BG108874A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HR20020231A HRP20020231A2 (en) 2002-03-18 2002-03-18 ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
US39361202P 2002-07-03 2002-07-03
US39470502P 2002-07-08 2002-07-08

Publications (1)

Publication Number Publication Date
BG108874A true BG108874A (en) 2005-12-30

Family

ID=28045976

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108874A BG108874A (en) 2002-03-18 2004-09-14 Isostructural pseudo-polymorphs of 9-deoxo-9a-aza-methyl-9a-homoerythromycin

Country Status (23)

Country Link
US (1) US7569549B2 (fr)
EP (2) EP1627883A1 (fr)
JP (1) JP2005529082A (fr)
KR (1) KR20050002872A (fr)
CN (1) CN1642966A (fr)
AT (1) ATE440104T1 (fr)
AU (1) AU2003215779A1 (fr)
BG (1) BG108874A (fr)
BR (1) BR0308644A (fr)
CA (1) CA2479211A1 (fr)
DE (1) DE60328872D1 (fr)
EA (1) EA200401217A1 (fr)
ES (1) ES2331733T3 (fr)
HR (2) HRP20020231A2 (fr)
IL (1) IL163836A0 (fr)
IS (1) IS7449A (fr)
MX (1) MXPA04009009A (fr)
NO (1) NO20044341L (fr)
NZ (1) NZ535477A (fr)
PL (1) PL372468A1 (fr)
RS (1) RS82504A (fr)
TN (1) TNSN04166A1 (fr)
WO (1) WO2003077830A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
HRP20020614A2 (en) * 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
EP1878432A1 (fr) * 2003-07-24 2008-01-16 Pliva - Research and Development Ltd. Azithromycine à dissolution rapide pour dose unique
EP1648473B1 (fr) * 2003-07-24 2009-01-28 PLIVA HRVATSKA d.o.o. Dose unique a dissolution rapide d'azithromycine
CA2547597A1 (fr) 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions multiparticulaires a stabilite amelioree
CN1889932A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 制备药用多颗粒的方法
MXPA06005913A (es) * 2003-12-04 2006-06-27 Pfizer Prod Inc Formas de dosificacion de multiparticulas de azitromicina por procedimientos basados en liquidos.
WO2005053652A1 (fr) 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions medicamenteuses cristallines multiparticulaires contenant un poloxamere et un glyceride
EP1689368B1 (fr) * 2003-12-04 2016-09-28 Bend Research, Inc Procédé d'atomisation/congélation faisant appel à une extrudeuse pour la préparation de compositions médicamenteuses cristallines multiparticulaires
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
UA27040C2 (uk) * 1987-07-09 2000-02-28 Пфайзер Інк. Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу
HRP20020231A2 (en) 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
DE69403963T2 (de) 1993-05-19 1997-11-20 Pfizer Zwischenprodukt für azithromycin
HRP940251B1 (en) 1994-04-15 1998-12-31 Stjepan Mutak Process for the preparation of azithromycin dihydrochloride
ES2122905B1 (es) * 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
PT102130A (pt) 1998-03-13 1999-09-30 Hovione Sociedade Quimica S A Processo de preparacao de dihidrato de azitromicina
CN1205338A (zh) 1998-05-08 1999-01-20 刘万忠 阿奇霉素水溶性盐的合成新方法及其在医药上的用途
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (fr) 1998-08-21 2002-01-29 Apotex Inc. Clathrate d'isopropanol monohydrate d'azithromycine et methodes d'obtention
CN1273142C (zh) * 1998-11-30 2006-09-06 特瓦制药工业有限公司 阿齐霉素的乙醇化物,制备方法以及医药组合物
AU5820400A (en) * 1999-06-29 2001-01-31 Biochemie S.A. Macrolides
ES2177373B1 (es) * 1999-11-26 2003-11-01 Astur Pharma Sa Preparacion de azitromicina en su forma no cristalina
PT1246831E (pt) * 2000-01-04 2008-03-28 Teva Pharma Método de preparação de di-hidrato de azitromicina
ES2162764B1 (es) * 2000-05-17 2003-04-01 Ercros Ind Sa Forma polimorfica del dihidrato de azitromicina, y su procedimiento deobtencion.
ATE320441T1 (de) * 2000-07-25 2006-04-15 Silanes Sa De Cv Lab Einstufiges verfahren zur herstellung von 7,16-
DE60114028T2 (de) * 2000-08-23 2006-07-13 Wockhardt Ltd. Verfahren zur herstellung von wasserfreiem azithromycin
US6949519B2 (en) 2000-11-27 2005-09-27 Sandoz Ag Macrolide solvates
KR100491183B1 (ko) 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
KR100431431B1 (ko) 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
HRP20010301A2 (en) 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
US6861413B2 (en) * 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
NZ529118A (en) * 2001-05-22 2005-10-28 Pfizer Prod Inc Crystal forms of azithromycin
NZ532707A (en) * 2001-12-21 2006-07-28 Pfizer Prod Inc Directly compressible formulations of azithromycin
IL161259A0 (en) 2001-12-21 2004-09-27 Pfizer Prod Inc Methods for wet granulating azithromycin
NZ534234A (en) 2002-02-01 2007-05-31 Pfizer Prod Inc Dry granulated formulations of non-dihydrate form of azithromycin
ITMI20021209A1 (it) 2002-06-04 2003-12-04 Chemi Spa Processo di preparazione di azitromicina ad elevata purezza

Also Published As

Publication number Publication date
US20040014951A1 (en) 2004-01-22
WO2003077830A2 (fr) 2003-09-25
EA200401217A1 (ru) 2005-02-24
NO20044341L (no) 2004-11-23
ATE440104T1 (de) 2009-09-15
WO2003077830A3 (fr) 2004-05-13
PL372468A1 (en) 2005-07-25
NZ535477A (en) 2006-11-30
HRP20040858A2 (en) 2005-06-30
HRP20020231A2 (en) 2003-12-31
JP2005529082A (ja) 2005-09-29
MXPA04009009A (es) 2005-06-17
EP1627883A1 (fr) 2006-02-22
IS7449A (is) 2004-09-16
DE60328872D1 (en) 2009-10-01
TNSN04166A1 (en) 2007-03-12
CN1642966A (zh) 2005-07-20
KR20050002872A (ko) 2005-01-10
BR0308644A (pt) 2005-01-25
RS82504A (en) 2006-12-15
EP1485393A2 (fr) 2004-12-15
AU2003215779A1 (en) 2003-09-29
IL163836A0 (en) 2005-12-18
CA2479211A1 (fr) 2003-09-25
US7569549B2 (en) 2009-08-04
ES2331733T3 (es) 2010-01-14
EP1485393B1 (fr) 2009-08-19

Similar Documents

Publication Publication Date Title
JO2410B1 (en) 6. Replaced pyrido-pyrimidines
SG143985A1 (en) Quinolinone derivatives
SG145694A1 (en) Novel compounds
GEP20084399B (en) Crystal forms of azithromycin
AU5646801A (en) Light-emitting devices
MY140987A (en) Specific glucocorticosteroid compound having anti-inflammatory activity
AU2002367580A8 (en) Tissue-engineered organs
SG141459A1 (en) Novel quinoline derivatives
AU2003210409A1 (en) Flame retardant compositions
AU2003241789A1 (en) Flame retardant composition
AU2003271717A1 (en) Flame retardant composition
BG108874A (en) Isostructural pseudo-polymorphs of 9-deoxo-9a-aza-methyl-9a-homoerythromycin
HK1045990A1 (en) Novel derivatives and analogues of galanthamin.
GB0221069D0 (en) Sterile environments
AU2003290592A1 (en) Antitumor benzoylsulfonamides
AU2001294871A1 (en) Flame-retardant composition
AU2001259482A1 (en) Extreme-uv electrical discharge source
GB2363676B (en) Plasma source
PL377176A1 (pl) N-Sulfonylo-4-metylenoamino-3-hydroksy-2-pirydony
AU148078S (en) Bottle
MXPA06000372A (es) Compuestos de silicio y su uso.
AU2003276948A1 (en) Duct fastseam
PL370227A1 (en) Anthelmintic composition
CA97229S (en) Escutcheon
GB2379315A8 (en) Luminous house numbers