ATE320441T1 - Einstufiges verfahren zur herstellung von 7,16- - Google Patents

Einstufiges verfahren zur herstellung von 7,16-

Info

Publication number
ATE320441T1
ATE320441T1 AT00959035T AT00959035T ATE320441T1 AT E320441 T1 ATE320441 T1 AT E320441T1 AT 00959035 T AT00959035 T AT 00959035T AT 00959035 T AT00959035 T AT 00959035T AT E320441 T1 ATE320441 T1 AT E320441T1
Authority
AT
Austria
Prior art keywords
erythromycin
iminoether
aza
step process
mesitylenesulfonyloxime
Prior art date
Application number
AT00959035T
Other languages
English (en)
Inventor
La Torre Garcia Juan Antoni De
Andrade Fidencio Franco
Ochoa Jose Manuel Francis Lara
Original Assignee
Silanes Sa De Cv Lab
Inst De Investigacion En Quimi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Silanes Sa De Cv Lab, Inst De Investigacion En Quimi filed Critical Silanes Sa De Cv Lab
Application granted granted Critical
Publication of ATE320441T1 publication Critical patent/ATE320441T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00959035T 2000-07-25 2000-07-25 Einstufiges verfahren zur herstellung von 7,16- ATE320441T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/MX2000/000030 WO2002010144A1 (es) 2000-07-25 2000-07-25 PROCESO PARA LA PREPARACION EN UN SOLO PASO DE 7,16-DIOXA-2-AZA-10-O-CLADINOSIL-12-O-DESOSAMINIL-4,5-DIHIDROXI-6-ETIL-3,5,9,11,13,15-HEXAMETILBICICLO[11.2.1]HEXADECA-1(2)-EN-8-ONA Y OBTENCION DE UNA FORMA NUEVA DE 9-DESOXO-9a-AZA-9a-METIL-9a-HOMOERITROMICINA A

Publications (1)

Publication Number Publication Date
ATE320441T1 true ATE320441T1 (de) 2006-04-15

Family

ID=19741683

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00959035T ATE320441T1 (de) 2000-07-25 2000-07-25 Einstufiges verfahren zur herstellung von 7,16-

Country Status (8)

Country Link
US (1) US6528492B1 (de)
EP (1) EP1304326B1 (de)
AT (1) ATE320441T1 (de)
AU (1) AU2000270425A1 (de)
CA (1) CA2417353C (de)
DE (1) DE60026718T2 (de)
ES (1) ES2260047T3 (de)
WO (1) WO2002010144A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) * 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
EE200300575A (et) 2001-05-22 2004-04-15 Pfizer Products Inc. Asitromütsiini kristalsed vormid
HRP20020614A2 (en) * 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
WO2007080507A2 (en) * 2006-01-12 2007-07-19 Wockhardt Ltd Processes for the preparation of azithromycin
US20120058936A1 (en) 2009-03-13 2012-03-08 Assistance Publique - Hopitaux De Paris Compositions and methods for elimination of gram negative bacteria
CN103087125B (zh) * 2013-02-06 2015-12-02 浙江国邦药业有限公司 制备阿奇霉素一锅煮的工艺方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
YU43116B (en) 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
UA27040C2 (uk) 1987-07-09 2000-02-28 Пфайзер Інк. Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу
WO1989002271A1 (en) 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
ATE154806T1 (de) 1993-05-19 1997-07-15 Pfizer Zwischenprodukt für azithromycin
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
ES2122905B1 (es) * 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
PT102006B (pt) 1997-05-19 2000-06-30 Hovione Sociedade Quimica S A Novo processo de preparacao de azitromicina
TW546302B (en) 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
GB9824580D0 (en) * 1998-11-10 1999-01-06 Biochemie Sa Organic compounds
ATE334136T1 (de) 1999-06-29 2006-08-15 Sandoz Ag Verfahren zur herstellung von azithromycin
WO2002009640A2 (en) 2000-08-01 2002-02-07 Shiva Prasad Singh Process for the preparation of anhydrous azithromycin
DE60114028T2 (de) 2000-08-23 2006-07-13 Wockhardt Ltd. Verfahren zur herstellung von wasserfreiem azithromycin

Also Published As

Publication number Publication date
ES2260047T3 (es) 2006-11-01
US6528492B1 (en) 2003-03-04
DE60026718D1 (de) 2006-05-11
AU2000270425A1 (en) 2002-02-13
EP1304326A4 (de) 2004-06-16
EP1304326A1 (de) 2003-04-23
EP1304326B1 (de) 2006-03-15
WO2002010144A1 (es) 2002-02-07
DE60026718T2 (de) 2006-11-16
CA2417353C (en) 2009-09-01
CA2417353A1 (en) 2003-01-27

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