BG107677A - Аза - и полиаза - нафталенил карбоксамиди, приложими като инхибитори на hiv интеграза - Google Patents

Аза - и полиаза - нафталенил карбоксамиди, приложими като инхибитори на hiv интеграза Download PDF

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Publication number
BG107677A
BG107677A BG107677A BG10767703A BG107677A BG 107677 A BG107677 A BG 107677A BG 107677 A BG107677 A BG 107677A BG 10767703 A BG10767703 A BG 10767703A BG 107677 A BG107677 A BG 107677A
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BG
Bulgaria
Prior art keywords
alkyl
fluoroalkyl
substituted
phenyl
hydroxy
Prior art date
Application number
BG107677A
Other languages
Bulgarian (bg)
English (en)
Inventor
Neville Anthony
Robert Gomez
Steven Young
Melissa Egbertson
John Wai
Linghang Zhuang
Mark Embrey
Lekhanh Tran
Jeffrey Melamed
Marie Langford
James Guare
Thorsten FISHER
Samson JOLLY
Michelle KUO
Debra Perlow
Jennifer Bennett
Timothy FUNK
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of BG107677A publication Critical patent/BG107677A/bg

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG107677A 2000-10-12 2003-03-26 Аза - и полиаза - нафталенил карбоксамиди, приложими като инхибитори на hiv интеграза BG107677A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23970700P 2000-10-12 2000-10-12
US28165601P 2001-04-05 2001-04-05
PCT/US2001/042564 WO2002030931A2 (fr) 2000-10-12 2001-10-09 Aza-naphtalenyle carboxamides et polyaza-naphtalenyle carboxamides utiles en tant qu'inhibiteurs de l'integrase du vih

Publications (1)

Publication Number Publication Date
BG107677A true BG107677A (bg) 2003-11-28

Family

ID=26932782

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107677A BG107677A (bg) 2000-10-12 2003-03-26 Аза - и полиаза - нафталенил карбоксамиди, приложими като инхибитори на hiv интеграза

Country Status (26)

Country Link
US (2) US6921759B2 (fr)
EP (1) EP1326865B1 (fr)
JP (1) JP4252797B2 (fr)
KR (1) KR20030036922A (fr)
CN (1) CN1469878A (fr)
AR (1) AR033845A1 (fr)
AT (1) ATE430745T1 (fr)
AU (3) AU1152702A (fr)
BG (1) BG107677A (fr)
BR (1) BR0114610A (fr)
CA (1) CA2425440C (fr)
CZ (1) CZ20031028A3 (fr)
DE (1) DE60138635D1 (fr)
EA (1) EA200300449A1 (fr)
EE (1) EE200300145A (fr)
HU (1) HUP0302367A2 (fr)
IL (1) IL155089A0 (fr)
IS (1) IS6760A (fr)
MX (1) MXPA03003263A (fr)
NO (1) NO20031672L (fr)
NZ (1) NZ525088A (fr)
PE (1) PE20020509A1 (fr)
PL (1) PL360944A1 (fr)
SK (1) SK4322003A3 (fr)
WO (2) WO2002030930A2 (fr)
YU (1) YU27903A (fr)

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PL360944A1 (en) 2004-09-20
AU1152702A (en) 2002-04-22
WO2002030931A2 (fr) 2002-04-18
SK4322003A3 (en) 2003-09-11
JP4252797B2 (ja) 2009-04-08
NO20031672L (no) 2003-06-05
AU2002211874A1 (en) 2002-04-22
YU27903A (sh) 2006-05-25
EP1326865A2 (fr) 2003-07-16
US20030055071A1 (en) 2003-03-20
CA2425440A1 (fr) 2002-04-18
ATE430745T1 (de) 2009-05-15
CA2425440C (fr) 2010-04-13
JP2004511483A (ja) 2004-04-15
IS6760A (is) 2003-03-27
WO2002030930A2 (fr) 2002-04-18
US20050176718A1 (en) 2005-08-11
CN1469878A (zh) 2004-01-21
AU2002211527B2 (en) 2006-08-24
HUP0302367A2 (hu) 2003-11-28
US6921759B2 (en) 2005-07-26
DE60138635D1 (de) 2009-06-18
EA200300449A1 (ru) 2003-10-30
CZ20031028A3 (cs) 2003-08-13
AR033845A1 (es) 2004-01-07
WO2002030930A3 (fr) 2002-08-29
EE200300145A (et) 2003-06-16
BR0114610A (pt) 2005-12-13
MXPA03003263A (es) 2003-06-06
NO20031672D0 (no) 2003-04-11
IL155089A0 (en) 2003-10-31
KR20030036922A (ko) 2003-05-09
NZ525088A (en) 2004-11-26
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