BG106369A - Метод за получаване на изотретиноин - Google Patents

Метод за получаване на изотретиноин Download PDF

Info

Publication number
BG106369A
BG106369A BG106369A BG10636902A BG106369A BG 106369 A BG106369 A BG 106369A BG 106369 A BG106369 A BG 106369A BG 10636902 A BG10636902 A BG 10636902A BG 106369 A BG106369 A BG 106369A
Authority
BG
Bulgaria
Prior art keywords
acid
isotretinoin
formula
solvent
water
Prior art date
Application number
BG106369A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mohammad Salman
Kaul Vijay Kumar
J. Babu
Naresh Kumar
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IN1037DE1999 external-priority patent/IN190846B/en
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of BG106369A publication Critical patent/BG106369A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
BG106369A 1999-07-30 2002-01-30 Метод за получаване на изотретиноин BG106369A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1037DE1999 IN190846B (et) 1999-07-30 1999-07-30
US09/467,201 US6441226B1 (en) 1999-07-30 1999-12-20 Process for the preparation of isotretinoin
PCT/IB2000/001020 WO2001009089A1 (en) 1999-07-30 2000-07-24 Process for the preparation of isotretinoin

Publications (1)

Publication Number Publication Date
BG106369A true BG106369A (bg) 2002-08-30

Family

ID=26324696

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106369A BG106369A (bg) 1999-07-30 2002-01-30 Метод за получаване на изотретиноин

Country Status (24)

Country Link
EP (1) EP1204637B1 (et)
JP (1) JP2003506349A (et)
CN (1) CN1167679C (et)
AP (1) AP2002002414A0 (et)
AT (1) ATE293596T1 (et)
AU (1) AU778584B2 (et)
BG (1) BG106369A (et)
BR (1) BR0012866A (et)
CA (1) CA2380026A1 (et)
DE (1) DE60019611T2 (et)
EA (1) EA004651B1 (et)
EE (1) EE200200053A (et)
ES (1) ES2240117T3 (et)
HK (1) HK1046901B (et)
HR (1) HRP20020098A2 (et)
HU (1) HUP0202230A3 (et)
IL (1) IL147918A0 (et)
MX (1) MXPA02001107A (et)
OA (1) OA12002A (et)
PL (1) PL353491A1 (et)
PT (1) PT1204637E (et)
SK (1) SK1612002A3 (et)
TR (1) TR200200455T2 (et)
WO (1) WO2001009089A1 (et)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104447459A (zh) * 2014-11-28 2015-03-25 重庆华邦制药有限公司 异维a酸的新晶型及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951853A (en) * 1957-06-08 1960-09-06 Sumitomo Chemical Co Method for preparing polyenecarboxylic acid derivatives

Also Published As

Publication number Publication date
PL353491A1 (en) 2003-11-17
EA004651B1 (ru) 2004-06-24
DE60019611T2 (de) 2006-03-02
ATE293596T1 (de) 2005-05-15
JP2003506349A (ja) 2003-02-18
CN1371362A (zh) 2002-09-25
HUP0202230A2 (hu) 2002-11-28
HUP0202230A3 (en) 2004-03-01
HK1046901A1 (en) 2003-01-30
PT1204637E (pt) 2005-08-31
AU5838800A (en) 2001-02-19
TR200200455T2 (tr) 2002-07-22
CN1167679C (zh) 2004-09-22
OA12002A (en) 2006-04-18
EA200200110A1 (ru) 2002-08-29
EP1204637B1 (en) 2005-04-20
ES2240117T3 (es) 2005-10-16
EE200200053A (et) 2003-04-15
AU778584B2 (en) 2004-12-09
DE60019611D1 (de) 2005-05-25
IL147918A0 (en) 2002-08-14
HK1046901B (zh) 2005-09-23
MXPA02001107A (es) 2002-08-20
WO2001009089A1 (en) 2001-02-08
CA2380026A1 (en) 2001-02-08
SK1612002A3 (en) 2002-06-04
AP2002002414A0 (en) 2002-03-31
BR0012866A (pt) 2002-07-09
HRP20020098A2 (en) 2003-12-31
EP1204637A1 (en) 2002-05-15

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