BG104617A - Нови, с нафтил- и анилид-заместени сулфонамиди - Google Patents

Нови, с нафтил- и анилид-заместени сулфонамиди

Info

Publication number
BG104617A
BG104617A BG104617A BG10461700A BG104617A BG 104617 A BG104617 A BG 104617A BG 104617 A BG104617 A BG 104617A BG 10461700 A BG10461700 A BG 10461700A BG 104617 A BG104617 A BG 104617A
Authority
BG
Bulgaria
Prior art keywords
substituted
sulfonamides
anilide
novel naphthyl
naphthyl
Prior art date
Application number
BG104617A
Other languages
English (en)
Inventor
Wolfgang Bender
Juergen Reefschlaeger
Peter Eckenberg
Siegfried Goldmann
Michael Haerter
Sabine Hallenberger
Joerg Trappe
Olaf Weber
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG104617A publication Critical patent/BG104617A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретението се отнася до нови нафтил- и анилидзаместени сулфонамиди с обща формула@@в която заместителите А, D, E, G, R1, R2, R3, R4 и Х имат значенията, посочени в описанието, както и до метод за тяхното получаване и приложението им като противовирусни средства, по-специално срещу цитомегаловируси.
BG104617A 1998-01-23 2000-07-17 Нови, с нафтил- и анилид-заместени сулфонамиди BG104617A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19802439 1998-01-23
PCT/EP1999/000099 WO1999037609A1 (de) 1998-01-23 1999-01-09 Neue naphthyl- und anilid-substituierte sulfonamide

Publications (1)

Publication Number Publication Date
BG104617A true BG104617A (bg) 2001-04-30

Family

ID=7855411

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104617A BG104617A (bg) 1998-01-23 2000-07-17 Нови, с нафтил- и анилид-заместени сулфонамиди

Country Status (30)

Country Link
US (1) US6417181B1 (bg)
EP (1) EP1049666B1 (bg)
JP (1) JP2002501043A (bg)
KR (1) KR20010034321A (bg)
CN (1) CN1294578A (bg)
AR (1) AR016978A1 (bg)
AT (1) ATE242207T1 (bg)
AU (1) AU2420799A (bg)
BG (1) BG104617A (bg)
BR (1) BR9907738A (bg)
CA (1) CA2318182A1 (bg)
CO (1) CO4810231A1 (bg)
DE (1) DE59905829D1 (bg)
EE (1) EE200000432A (bg)
ES (1) ES2201666T3 (bg)
GT (1) GT199900010A (bg)
HR (1) HRP20000532A2 (bg)
HU (1) HUP0200918A2 (bg)
ID (1) ID25448A (bg)
IL (1) IL137159A0 (bg)
NO (1) NO20003601L (bg)
NZ (1) NZ505900A (bg)
PE (1) PE20000181A1 (bg)
PL (1) PL341815A1 (bg)
SK (1) SK11012000A3 (bg)
SV (1) SV1999000006A (bg)
TR (1) TR200002140T2 (bg)
TW (1) TW461880B (bg)
WO (1) WO1999037609A1 (bg)
ZA (1) ZA99473B (bg)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19919793A1 (de) * 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
DE19920790A1 (de) * 1999-05-06 2000-11-09 Bayer Ag Bis-Sulfonamide mit anti-HCMV-Wirkung
DE19934295A1 (de) * 1999-07-21 2001-01-25 Bayer Ag Kristallmodifikation III von N-(4-(5-Dimethylamino-naphthalin-1-sulfonyl-amino)-phenyl)-3-hydroxy-2,2-dimethyl-propionamid
DE19934321A1 (de) * 1999-07-21 2001-01-25 Bayer Ag Naphthyl-substituierte Sulfonamide
US7547716B2 (en) * 2001-06-08 2009-06-16 Institute Of Medicinal Molecular Design, Inc. Sulfonamide derivatives
GB2403474B (en) * 2002-04-18 2006-10-11 Inst Med Molecular Design Inc Amide derivatives
US7491827B2 (en) 2002-12-23 2009-02-17 Millennium Pharmaceuticals, Inc. Aryl sulfonamides useful as inhibitors of chemokine receptor activity
EP1590327A1 (en) 2002-12-23 2005-11-02 Millennium Pharmaceuticals, Inc. Ccr8 inhibitors
TW200510311A (en) 2002-12-23 2005-03-16 Millennium Pharm Inc CCr8 inhibitors
US7425527B2 (en) 2004-06-04 2008-09-16 The Procter & Gamble Company Organic activator
RU2452490C1 (ru) * 2010-12-27 2012-06-10 Виктор Вениаминович Тец Лекарственное средство с активностью против семейства герпес-вирусов
AU2013257951A1 (en) 2012-05-11 2015-01-22 Akron Molecules Ag Use of compounds for the treatment of pain
RU2530587C1 (ru) 2013-06-07 2014-10-10 Виктор Вениаминович Тец Способ лечения заболеваний кожи и слизистых оболочек, вызываемых вирусами простого герпеса 1-го и 2-го типов
RU2605602C1 (ru) * 2015-09-15 2016-12-27 Общество с ограниченной ответственностью "Новые Антибиотики" Способ получения натриевой соли (2,6-дихлорфенил)амида карбопентоксисульфаниловой кислоты
CN112062901B (zh) * 2020-08-14 2023-03-21 合肥工业大学 一种螺旋荧光异腈共聚物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2423572A (en) * 1946-05-03 1947-07-08 Du Pont Naphtholsulfonamidobenzaldehydes and acetals thereof
US2949479A (en) * 1954-06-17 1960-08-16 Dainippon Pharmaceutical Co Acyl derivatives of aminonaphthalene-sulfonamide
US3482971A (en) 1967-07-24 1969-12-09 Polaroid Corp Scavengers for oxidized developing agent
US3925347A (en) 1967-07-24 1975-12-09 Polaroid Corp Processes of synthesizing azo compounds
US4035401A (en) 1970-03-30 1977-07-12 Polaroid Corporation Intermediates for photographic dyes
JPS5499433A (en) 1978-01-20 1979-08-06 Konishiroku Photo Ind Co Ltd Dye image formation method
DE3863375D1 (de) 1987-03-19 1991-08-01 Agfa Gevaert Nv Organische verbindungen fuer das farbstoffdiffusionsuebertragungsverfahren und diese verbindungen enthaltende photographische elemente.
WO1990009787A1 (en) * 1989-02-27 1990-09-07 The Du Pont Merck Pharmaceutical Company Novel sulfonamides as radiosensitizers
DE4331134A1 (de) 1993-09-14 1995-03-16 Bayer Ag Neue antiviral wirksame Pseudopeptide
EP0684515A1 (en) 1994-05-27 1995-11-29 Eastman Kodak Company Photographic element and process incorporating a high dye-yield image coupler providing improved granularity

Also Published As

Publication number Publication date
PE20000181A1 (es) 2000-04-12
ID25448A (id) 2000-10-05
ATE242207T1 (de) 2003-06-15
AU2420799A (en) 1999-08-09
US6417181B1 (en) 2002-07-09
CO4810231A1 (es) 1999-06-30
KR20010034321A (ko) 2001-04-25
IL137159A0 (en) 2001-07-24
ZA99473B (en) 1999-07-27
ES2201666T3 (es) 2004-03-16
TR200002140T2 (tr) 2000-12-21
NO20003601D0 (no) 2000-07-13
SV1999000006A (es) 2000-10-09
CA2318182A1 (en) 1999-07-29
BR9907738A (pt) 2000-10-17
EP1049666B1 (de) 2003-06-04
EP1049666A1 (de) 2000-11-08
HUP0200918A2 (en) 2002-09-28
WO1999037609A1 (de) 1999-07-29
GT199900010A (es) 2000-07-15
EE200000432A (et) 2001-12-17
TW461880B (en) 2001-11-01
NO20003601L (no) 2000-09-14
AR016978A1 (es) 2001-08-01
SK11012000A3 (sk) 2001-01-18
DE59905829D1 (de) 2003-07-10
HRP20000532A2 (en) 2001-02-28
CN1294578A (zh) 2001-05-09
JP2002501043A (ja) 2002-01-15
PL341815A1 (en) 2001-05-07
NZ505900A (en) 2002-02-01

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