BG105847A - Калцилитни съединения - Google Patents
Калцилитни съединенияInfo
- Publication number
- BG105847A BG105847A BG105847A BG10584701A BG105847A BG 105847 A BG105847 A BG 105847A BG 105847 A BG105847 A BG 105847A BG 10584701 A BG10584701 A BG 10584701A BG 105847 A BG105847 A BG 105847A
- Authority
- BG
- Bulgaria
- Prior art keywords
- calcilytic compounds
- compounds
- calcilytic
- meanings
- substituents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/57—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Изобретението се отнася до нови калцилитни съединения с формула, в която значенията на заместителите са посочени в описанието. Съединенията намират приложение като калциеви рецепторни антагонисти.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11824099P | 1999-02-02 | 1999-02-02 | |
PCT/US2000/002676 WO2000045816A1 (en) | 1999-02-02 | 2000-02-02 | Calcilytic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105847A true BG105847A (bg) | 2002-04-30 |
Family
ID=22377367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105847A BG105847A (bg) | 1999-02-02 | 2001-08-27 | Калцилитни съединения |
Country Status (24)
Country | Link |
---|---|
US (1) | US6417215B1 (bg) |
EP (1) | EP1148876A4 (bg) |
JP (1) | JP2002536330A (bg) |
KR (1) | KR20010093285A (bg) |
CN (1) | CN1346269A (bg) |
AP (1) | AP2001002220A0 (bg) |
AU (1) | AU3480200A (bg) |
BG (1) | BG105847A (bg) |
BR (1) | BR0007922A (bg) |
CA (1) | CA2361589A1 (bg) |
CO (1) | CO5251439A1 (bg) |
CZ (1) | CZ20012797A3 (bg) |
EA (1) | EA200100854A1 (bg) |
HK (1) | HK1042036A1 (bg) |
HU (1) | HUP0200121A3 (bg) |
ID (1) | ID29533A (bg) |
IL (1) | IL144470A0 (bg) |
MA (1) | MA25379A1 (bg) |
NO (1) | NO20013769L (bg) |
OA (1) | OA11757A (bg) |
PE (1) | PE20001456A1 (bg) |
SK (1) | SK10982001A3 (bg) |
WO (1) | WO2000045816A1 (bg) |
ZA (1) | ZA200106298B (bg) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1308436B1 (en) * | 2000-08-11 | 2008-10-15 | Japan Tobacco Inc. | Calcium receptor antagonists |
AU2002230579A1 (en) * | 2000-10-25 | 2002-05-06 | Smithkline Beecham Corp | Calcilytic compounds |
US6864267B2 (en) * | 2001-07-16 | 2005-03-08 | Smithkline Beecham Corporation | Calcilytic compounds |
TWI316511B (en) * | 2002-11-26 | 2009-11-01 | Smithkline Beecham Corp | Calcilytic compounds |
WO2004069793A2 (en) | 2003-01-28 | 2004-08-19 | Bristol-Myers Squibb Company | Novel 2-substituted cyclic amines as calcium sensing receptor modulators |
US7205322B2 (en) | 2003-02-12 | 2007-04-17 | Bristol-Myers Squibb Company | Thiazolidine compounds as calcium sensing receptor modulators |
KR100696927B1 (ko) | 2003-04-23 | 2007-03-20 | 니뽄 다바코 산교 가부시키가이샤 | CaSR 길항제 |
CA2527203C (en) | 2003-05-28 | 2010-08-17 | Japan Tobacco Inc. | Casr antagonist |
US7265145B2 (en) | 2003-05-28 | 2007-09-04 | Bristol-Myers Squibb Company | Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method |
EP1964548A1 (en) * | 2007-03-02 | 2008-09-03 | Novartis AG | Pharmaceutical compositions comprising a calcilytic agent |
WO2009148052A1 (ja) | 2008-06-05 | 2009-12-10 | 旭化成ファーマ株式会社 | スルホンアミド化合物及びその用途 |
WO2010103429A1 (en) | 2009-03-10 | 2010-09-16 | Pfizer Inc. | 1,1-(Dimethyl-Ethylamino)-2-Hydroxy-Propoxy]-Ethyl}-3-Methyl-Biphenyl-4- Carboxylic Acid Derivatives As Calcium Receptor Antagonists |
GB201217330D0 (en) | 2012-09-28 | 2012-11-14 | Univ Cardiff | Therapeutic for treating inflammatory lung disorders |
WO2021029517A1 (en) * | 2019-08-13 | 2021-02-18 | Dongguk University Industry-Academic Cooperation Foundation | Pharmaceutical composition for improving or treating post-surgical hypoparathyroidism and treatment method using the same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE122007000050I1 (de) | 1990-02-19 | 2007-11-08 | Novartis Ag | Acylverbindungen |
DE4102024A1 (de) * | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
JP2001501584A (ja) * | 1996-04-09 | 2001-02-06 | エヌピーエス・ファーマシウティカルズ・インコーポレイテッド | カルシリチック化合物 |
UY24949A1 (es) * | 1997-04-08 | 2001-04-30 | Smithkline Beecham Corp | Compuestos calcilíticos |
-
2000
- 2000-02-01 PE PE2000000070A patent/PE20001456A1/es not_active Application Discontinuation
- 2000-02-02 CA CA002361589A patent/CA2361589A1/en not_active Abandoned
- 2000-02-02 EA EA200100854A patent/EA200100854A1/ru unknown
- 2000-02-02 IL IL14447000A patent/IL144470A0/xx unknown
- 2000-02-02 US US09/890,310 patent/US6417215B1/en not_active Expired - Lifetime
- 2000-02-02 CZ CZ20012797A patent/CZ20012797A3/cs unknown
- 2000-02-02 WO PCT/US2000/002676 patent/WO2000045816A1/en not_active Application Discontinuation
- 2000-02-02 JP JP2000596936A patent/JP2002536330A/ja not_active Withdrawn
- 2000-02-02 KR KR1020017009467A patent/KR20010093285A/ko not_active Application Discontinuation
- 2000-02-02 AP APAP/P/2001/002220A patent/AP2001002220A0/en unknown
- 2000-02-02 OA OA1200100199A patent/OA11757A/en unknown
- 2000-02-02 CO CO00006199A patent/CO5251439A1/es unknown
- 2000-02-02 ID IDW00200101673A patent/ID29533A/id unknown
- 2000-02-02 BR BR0007922-7A patent/BR0007922A/pt not_active IP Right Cessation
- 2000-02-02 SK SK1098-2001A patent/SK10982001A3/sk unknown
- 2000-02-02 HU HU0200121A patent/HUP0200121A3/hu unknown
- 2000-02-02 EP EP00913335A patent/EP1148876A4/en not_active Withdrawn
- 2000-02-02 CN CN00805996A patent/CN1346269A/zh active Pending
- 2000-02-02 AU AU34802/00A patent/AU3480200A/en not_active Abandoned
-
2001
- 2001-07-31 ZA ZA200106298A patent/ZA200106298B/en unknown
- 2001-08-01 NO NO20013769A patent/NO20013769L/no not_active Application Discontinuation
- 2001-08-01 MA MA26283A patent/MA25379A1/fr unknown
- 2001-08-27 BG BG105847A patent/BG105847A/bg unknown
-
2002
- 2002-02-27 HK HK02101521.4A patent/HK1042036A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1148876A4 (en) | 2003-07-23 |
PE20001456A1 (es) | 2001-01-28 |
EA200100854A1 (ru) | 2002-02-28 |
ZA200106298B (en) | 2002-10-18 |
KR20010093285A (ko) | 2001-10-27 |
CO5251439A1 (es) | 2003-02-28 |
JP2002536330A (ja) | 2002-10-29 |
HUP0200121A2 (hu) | 2002-05-29 |
NO20013769L (no) | 2001-09-26 |
US6417215B1 (en) | 2002-07-09 |
EP1148876A1 (en) | 2001-10-31 |
MA25379A1 (fr) | 2002-04-01 |
CN1346269A (zh) | 2002-04-24 |
HK1042036A1 (zh) | 2002-08-02 |
IL144470A0 (en) | 2002-05-23 |
CZ20012797A3 (cs) | 2002-01-16 |
BR0007922A (pt) | 2001-11-06 |
WO2000045816A1 (en) | 2000-08-10 |
NO20013769D0 (no) | 2001-08-01 |
CA2361589A1 (en) | 2000-08-10 |
ID29533A (id) | 2001-09-06 |
AU3480200A (en) | 2000-08-25 |
HUP0200121A3 (en) | 2002-11-28 |
OA11757A (en) | 2005-07-19 |
SK10982001A3 (sk) | 2001-12-03 |
AP2001002220A0 (en) | 2001-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL155875A0 (en) | Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor | |
MY129613A (en) | Cannabinoid receptor binding compounds | |
MXPA02011977A (es) | Herbicidas de piridina sustituidas. | |
BG106585A (bg) | Киназни инхибитори като лекарствени средства | |
MY134568A (en) | Cb2 receptor agonists | |
ATE270817T1 (de) | Fungizide | |
DE60004066D1 (de) | Benzofurylpiperazine: 5-ht2c serotoninrezeptor agonisten | |
BG102704A (bg) | Фунгицидни 2-метоксибензофенони | |
BG106340A (bg) | Заместени оксоазахетероциклени съединения | |
BG105205A (bg) | Бифенилни сулфонамиди като двойни рецепторни антагонисти на ангиотензин и ендотелин | |
RS20050810A (en) | 5,7-diaminopyrazolo(4,3-d)pyrimidines useful in the treatment of hypertension | |
ATE469892T1 (de) | Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung | |
HK1068136A1 (en) | Muscarinic antagonists | |
BG105847A (bg) | Калцилитни съединения | |
BG104916A (bg) | Калцилитични съединения | |
MXPA04006266A (es) | Pirimidotriazinas como inhibidores de fosfatasa. | |
BG104915A (bg) | Азабициклични 5ht1 рецепторни лиганди | |
BG105710A (bg) | 5-нт1 антагонисти за антидепресантно лечение | |
MXPA03011630A (es) | Compuestos de amenoacetonitrilo para el control de endoparasitos. | |
SE9903290D0 (sv) | Novel compounds | |
RS56004A (en) | Triazolo-quinolin derivatives useful as adenosine receptor ligands | |
MXPA04005988A (es) | 3,4-dihidro-1h-isoquinolin-2-il-derivados. | |
MXPA05008601A (es) | Derivados de benzamida como agonistas de oxitocina y antagonistas de vasopresina. | |
GB0011071D0 (en) | Organic compounds | |
MX9603199A (es) | Antagonistas de receptores a endotelina. |