BE904316A - Procede de preparation d'ethers phenethyliques utilisant des intermediaires cycliques. - Google Patents
Procede de preparation d'ethers phenethyliques utilisant des intermediaires cycliques.Info
- Publication number
- BE904316A BE904316A BE0/216340A BE216340A BE904316A BE 904316 A BE904316 A BE 904316A BE 0/216340 A BE0/216340 A BE 0/216340A BE 216340 A BE216340 A BE 216340A BE 904316 A BE904316 A BE 904316A
- Authority
- BE
- Belgium
- Prior art keywords
- phenethyl
- ethers
- preparation
- cyclic intermediates
- branched
- Prior art date
Links
- -1 PHENETHYL ETHERS Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- WYNCHZVNFNFDNH-UHFFFAOYSA-N Oxazolidine Chemical compound C1COCN1 WYNCHZVNFNFDNH-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229960004324 betaxolol Drugs 0.000 abstract 1
- CHDPSNLJFOQTRK-UHFFFAOYSA-N betaxolol hydrochloride Chemical compound [Cl-].C1=CC(OCC(O)C[NH2+]C(C)C)=CC=C1CCOCC1CC1 CHDPSNLJFOQTRK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K5/00—Casings, cabinets or drawers for electric apparatus
- H05K5/0004—Casings, cabinets or drawers for electric apparatus comprising several parts forming a closed casing
- H05K5/0013—Casings, cabinets or drawers for electric apparatus comprising several parts forming a closed casing assembled by resilient members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Connector Housings Or Holding Contact Members (AREA)
- Casings For Electric Apparatus (AREA)
- Buckles (AREA)
- Clamps And Clips (AREA)
Abstract
Composés de la famille du bétaxolol de formule I où m est un entier de 2 à5, n est un entier de 1 à 4 et R est un groupe alkyle ramifié en C3 ou C4 ou un groupe cycloalkyle en C3 ou C4 et leurs sels d'addition d'acides. Pour préparer ces composés, on hydrolyse le composé protégé sous forme oxazolidine II où R' est un groupe aryle, aryle substitué ou alkyle à chaine droite ou ramifiée en C2-C11 et R, n et m ont les significations indiquées ci-dessous.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA000473827A CA1265523A (fr) | 1984-08-21 | 1985-02-07 | Preparation d'ethers phenoliques a l'aide d'intermediaires cycliques |
DE19853541610 DE3541610A1 (de) | 1985-02-07 | 1985-11-25 | Gehaeusegurt |
DE8533142U DE8533142U1 (de) | 1985-02-07 | 1985-11-25 | Gehäusegurt |
Publications (1)
Publication Number | Publication Date |
---|---|
BE904316A true BE904316A (fr) | 1986-06-16 |
Family
ID=37877040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/216340A BE904316A (fr) | 1985-02-07 | 1986-02-28 | Procede de preparation d'ethers phenethyliques utilisant des intermediaires cycliques. |
Country Status (12)
Country | Link |
---|---|
US (1) | US4760182A (fr) |
EP (1) | EP0223944A3 (fr) |
JP (1) | JPH0662519B2 (fr) |
BE (1) | BE904316A (fr) |
CH (1) | CH670637A5 (fr) |
DE (3) | DE3541610A1 (fr) |
ES (3) | ES8609190A1 (fr) |
FI (1) | FI91751C (fr) |
FR (1) | FR2576896B1 (fr) |
IT (1) | IT1191991B (fr) |
NL (1) | NL8600605A (fr) |
SE (1) | SE465461B (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE8814032U1 (de) * | 1988-11-09 | 1990-03-22 | Grote & Hartmann Gmbh & Co Kg, 5600 Wuppertal | Maschinell verarbeitbares Kunststoffgehäuse |
DE8814029U1 (de) * | 1988-11-09 | 1990-03-15 | Grote & Hartmann Gmbh & Co Kg, 5600 Wuppertal | Gurtbares Kunststoffgehäuse |
ES2011584A6 (es) * | 1989-05-26 | 1990-01-16 | Esteve Quimica Sa | Procedimiento industrial para la obtencion de una ariloxipropanolamina. |
US5003115A (en) * | 1990-03-28 | 1991-03-26 | Hoechst Celanese Corporation | Production of 4-hydroxyphenethyl alcohol |
KR960003498B1 (ko) * | 1992-06-18 | 1996-03-14 | 금성일렉트론주식회사 | 반도체장치의 캐패시터 제조방법 |
US5263876A (en) * | 1992-09-15 | 1993-11-23 | Amphenol Corporation | Modular EMI-EMP connector assembly |
DE4243598C2 (de) * | 1992-12-22 | 1996-05-15 | Grote & Hartmann | Gurteinrichtung für ein ein- oder mehrpoliges Kontaktgehäuse |
TW275614B (fr) * | 1993-02-15 | 1996-05-11 | Senju Pharma Co | |
EP0711002A3 (fr) | 1994-11-07 | 1997-01-02 | Grote & Hartmann | Boîtier de connexion pour un connecteur d'airbag et procédé pour contacter un boîtier de connexion |
DE4439786A1 (de) * | 1994-11-07 | 1996-05-09 | Grote & Hartmann | Airbag-Stecker |
US5942633A (en) * | 1996-06-19 | 1999-08-24 | Abbott Laboratories | Process for the selective alkylation of betaxolol intermediates |
US5731463A (en) * | 1996-09-23 | 1998-03-24 | Abbott Laboratories | Selective alkylation of an alcohol substituted phenol compound |
US7019172B2 (en) * | 2004-06-30 | 2006-03-28 | Council Of Scientific And Industrial Research | Process for preparation of S-(-)-betaxolol and salts thereof |
US6989465B1 (en) * | 2004-11-01 | 2006-01-24 | Council Of Scientific And Industrial Research | S-(−)-1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of S-(−)betaxolo |
CN1300079C (zh) * | 2004-12-03 | 2007-02-14 | 南京大学 | 合成4-[2-(环丙基甲氧基)乙基]苯酚的新工艺 |
CN111689868A (zh) * | 2020-07-03 | 2020-09-22 | 山东省食品药品检验研究院 | 1-【(4-羟乙基)苯氧基】-3-(异丙基氨基)丙-2-醇的制备方法与应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US27822A (en) * | 1860-04-10 | Isaac mott | ||
FR1336265A (fr) * | 1962-07-20 | 1963-08-30 | Wonder Piles | Boîte de raccordement pour pile ronde |
GB1128052A (en) * | 1965-06-08 | 1968-09-25 | Ici Ltd | Alkanolamine derivatives |
US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
NL6708605A (fr) * | 1967-06-21 | 1968-12-23 | ||
GB1285038A (en) * | 1969-02-21 | 1972-08-09 | Ici Ltd | Alkanolamine derivatives |
DE2147615C3 (de) * | 1971-09-23 | 1981-09-03 | Standard Elektrik Lorenz Ag, 7000 Stuttgart | Tragbares Gehäuse für elektrische Geräte |
US4018778A (en) * | 1972-05-24 | 1977-04-19 | Cassella Farbwerke Mainkur Aktiengesellschaft | Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production |
FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
DE2646616C3 (de) * | 1976-10-15 | 1980-08-07 | C. A. Weidmueller Kg, 4930 Detmold | Anreihbares Einbauteil |
GB2041254B (en) * | 1978-09-22 | 1982-09-22 | Burndy Corp | Method of forming electrical connectors |
DE2933818C2 (de) * | 1979-08-21 | 1982-05-06 | Siemens AG, 1000 Berlin und 8000 München | Gehäuse zur Aufnahme elektrischer Geräte |
FR2536390B1 (fr) * | 1982-11-22 | 1986-03-21 | Synthelabo | Isomere s du betaxolol, sa preparation et son application en therapeutique |
DE3335665A1 (de) * | 1983-08-04 | 1985-04-04 | Siemens AG, 1000 Berlin und 8000 München | Vorrichtung zum sichern der verbindung zweier gehaeuseschalen eines fuer die aufnahme elektrischer bauelemente bzw. baugruppen dienenden gehaeuses |
DE3328242A1 (de) * | 1983-08-04 | 1985-02-21 | Siemens AG, 1000 Berlin und 8000 München | Vorrichtung zum sichern der verbindung zweier gehaeuseschalen eines fuer die aufnahme elektrischer bauelemente bzw. baugruppen dienenden gehaeuses |
GB8330617D0 (en) * | 1983-11-16 | 1983-12-21 | Molex Inc | Electrical connectors |
DE3346243C2 (de) * | 1983-12-21 | 1986-09-18 | Siemens AG, 1000 Berlin und 8000 München | Schnappverbindung zwischen zwei Elementen |
-
1985
- 1985-07-02 ES ES544803A patent/ES8609190A1/es not_active Expired
- 1985-11-25 DE DE19853541610 patent/DE3541610A1/de active Granted
- 1985-11-25 DE DE8533142U patent/DE8533142U1/de not_active Expired
-
1986
- 1986-02-03 FI FI860492A patent/FI91751C/fi not_active IP Right Cessation
- 1986-02-04 IT IT67082/86A patent/IT1191991B/it active
- 1986-02-07 FR FR868601728A patent/FR2576896B1/fr not_active Expired
- 1986-02-17 ES ES552088A patent/ES8707942A1/es not_active Expired
- 1986-02-17 ES ES552089A patent/ES8707943A1/es not_active Expired
- 1986-02-25 US US06/832,637 patent/US4760182A/en not_active Expired - Fee Related
- 1986-02-27 SE SE8600887A patent/SE465461B/sv not_active IP Right Cessation
- 1986-02-27 CH CH794/86A patent/CH670637A5/fr not_active IP Right Cessation
- 1986-02-28 BE BE0/216340A patent/BE904316A/fr not_active IP Right Cessation
- 1986-03-07 NL NL8600605A patent/NL8600605A/nl not_active Application Discontinuation
- 1986-03-10 JP JP61052327A patent/JPH0662519B2/ja not_active Expired - Lifetime
- 1986-03-21 DE DE19863609679 patent/DE3609679A1/de not_active Withdrawn
- 1986-09-10 EP EP86112557A patent/EP0223944A3/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ES552088A0 (es) | 1987-09-01 |
CH670637A5 (fr) | 1989-06-30 |
FI860492A (fi) | 1986-08-08 |
SE8600887L (sv) | 1987-08-28 |
DE3541610A1 (de) | 1987-05-27 |
SE8600887D0 (sv) | 1986-02-27 |
ES552089A0 (es) | 1987-09-01 |
US4760182A (en) | 1988-07-26 |
FI91751B (fi) | 1994-04-29 |
DE3541610C2 (fr) | 1989-12-28 |
FI860492A0 (fi) | 1986-02-03 |
ES8609190A1 (es) | 1986-07-16 |
SE465461B (sv) | 1991-09-16 |
IT8667082A0 (it) | 1986-02-04 |
JPH0662519B2 (ja) | 1994-08-17 |
FI91751C (fi) | 1994-08-10 |
FR2576896B1 (fr) | 1989-02-17 |
IT1191991B (it) | 1988-03-31 |
NL8600605A (nl) | 1987-10-01 |
DE8533142U1 (de) | 1987-08-13 |
DE3609679A1 (de) | 1987-09-24 |
FR2576896A1 (fr) | 1986-08-08 |
ES544803A0 (es) | 1986-07-16 |
EP0223944A3 (fr) | 1988-10-05 |
ES8707942A1 (es) | 1987-09-01 |
JPS62212354A (ja) | 1987-09-18 |
EP0223944A2 (fr) | 1987-06-03 |
ES8707943A1 (es) | 1987-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: TORCAN CHEMICAL LTD Effective date: 19970228 |