BE903403A - Nouveaux derives de la pyridine, un procede pour leur preparation et compositions therapeutiques a base de ces derives - Google Patents

Nouveaux derives de la pyridine, un procede pour leur preparation et compositions therapeutiques a base de ces derives

Info

Publication number
BE903403A
BE903403A BE0/215703A BE215703A BE903403A BE 903403 A BE903403 A BE 903403A BE 0/215703 A BE0/215703 A BE 0/215703A BE 215703 A BE215703 A BE 215703A BE 903403 A BE903403 A BE 903403A
Authority
BE
Belgium
Prior art keywords
derivatives
preparation
therapeutic compositions
compositions based
methyl
Prior art date
Application number
BE0/215703A
Other languages
English (en)
Inventor
A Esanu
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of BE903403A publication Critical patent/BE903403A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Abstract

Des nouveaux dérivés de la (cyano-1 alcoyle-1 N-méthyle N-méthoxy phénéthyle)-alcoyl-amino-5 triméthyle-2,2,8 4H-dioxine-(4,5-c)-pyridine répondant à la formule (I), leurs sels thérapeutiquement acceptables ainsi qu'un procédé de préparation de ces dérivés consistant à faire réagir, en proportions stoechiométriques, la(cyano-1 R1-1)-méthyle-5 triméthyle-2,2,8 4H-dioxino-(4,5-c)-pyridine correspondante sur le chlorure de (N-méthyle N-(méthoxy-phénéthyle)-omega-alcoyle, en présence d'une quantité stoechiométrique d'hydrure de sodium, dans le diméthylsulfoxide, à une température comprise entre 15 et 65 degrés. L'invention concerne également des compositions thérapeutiques à base de ces dérivés.
BE0/215703A 1984-10-23 1985-10-09 Nouveaux derives de la pyridine, un procede pour leur preparation et compositions therapeutiques a base de ces derives BE903403A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848426738A GB8426738D0 (en) 1984-10-23 1984-10-23 Pyridine derivatives

Publications (1)

Publication Number Publication Date
BE903403A true BE903403A (fr) 1986-04-09

Family

ID=10568592

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215703A BE903403A (fr) 1984-10-23 1985-10-09 Nouveaux derives de la pyridine, un procede pour leur preparation et compositions therapeutiques a base de ces derives

Country Status (26)

Country Link
US (1) US4610990A (fr)
JP (1) JPS61106578A (fr)
AR (1) AR240942A1 (fr)
AT (1) AT393682B (fr)
BE (1) BE903403A (fr)
CA (1) CA1286300C (fr)
CH (1) CH665842A5 (fr)
DE (1) DE3537715A1 (fr)
DK (1) DK159319C (fr)
DZ (1) DZ851A1 (fr)
ES (1) ES8609329A1 (fr)
FI (1) FI82249C (fr)
FR (2) FR2571965B1 (fr)
GB (2) GB8426738D0 (fr)
HK (1) HK44388A (fr)
IE (1) IE58499B1 (fr)
IT (1) IT1190409B (fr)
LU (1) LU86117A1 (fr)
MA (1) MA20559A1 (fr)
MY (1) MY102281A (fr)
NL (1) NL8502788A (fr)
NO (1) NO163777C (fr)
OA (1) OA08125A (fr)
PT (1) PT81351B (fr)
SE (1) SE460904B (fr)
ZA (1) ZA857650B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3642331A1 (de) * 1986-12-11 1988-06-23 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel
JPH02102810U (fr) * 1989-01-31 1990-08-15
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
JPH02141516U (fr) * 1989-04-25 1990-11-28
US5395939A (en) * 1993-11-30 1995-03-07 North Carolina State University Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives

Also Published As

Publication number Publication date
SE460904B (sv) 1989-12-04
FR2572075A1 (fr) 1986-04-25
NO163777B (no) 1990-04-09
HK44388A (en) 1988-06-17
OA08125A (fr) 1987-03-31
NO854206L (no) 1986-04-24
US4610990A (en) 1986-09-09
MA20559A1 (fr) 1986-07-01
GB2165845B (en) 1988-01-06
DE3537715C2 (fr) 1992-04-09
ATA305785A (de) 1991-05-15
FR2572075B1 (fr) 1988-10-14
FI854088A0 (fi) 1985-10-21
JPS638114B2 (fr) 1988-02-19
NO163777C (no) 1990-07-18
FI82249C (fi) 1991-02-11
AR240942A1 (es) 1991-03-27
JPS61106578A (ja) 1986-05-24
AR240942A2 (es) 1991-03-27
SE8504825D0 (sv) 1985-10-16
FI854088L (fi) 1986-04-24
GB2165845A (en) 1986-04-23
GB8426738D0 (en) 1984-11-28
IE58499B1 (en) 1993-10-06
GB8524709D0 (en) 1985-11-13
IT8522597A0 (it) 1985-10-23
ES8609329A1 (es) 1986-09-01
ZA857650B (en) 1986-05-28
PT81351A (en) 1985-11-01
FR2571965B1 (fr) 1990-09-28
DE3537715A1 (de) 1986-04-24
CH665842A5 (fr) 1988-06-15
CA1286300C (fr) 1991-07-16
FR2571965A1 (fr) 1986-04-25
DK483185D0 (da) 1985-10-22
MY102281A (en) 1992-05-15
DK159319C (da) 1991-02-25
DZ851A1 (fr) 2004-09-13
ES548108A0 (es) 1986-09-01
DK483185A (da) 1986-04-24
LU86117A1 (fr) 1986-03-24
DK159319B (da) 1990-10-01
IE852609L (en) 1986-04-23
FI82249B (fi) 1990-10-31
SE8504825L (sv) 1986-04-24
IT1190409B (it) 1988-02-16
AT393682B (de) 1991-11-25
NL8502788A (nl) 1986-05-16
PT81351B (pt) 1987-11-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SOC. DE CONSEILS DE RECHERCHES ET D APPLICATIONS

Effective date: 19981031