AR240942A2 - Un proceso para la preparacion de nuevos derivados de 5-(1-ciano-1-alquil-n-mentil-n-metoxi-fenetil)-alquilamino-2.2.8.-trimetil-4h-dioxino-(4,5-c)-piridina.- - Google Patents

Un proceso para la preparacion de nuevos derivados de 5-(1-ciano-1-alquil-n-mentil-n-metoxi-fenetil)-alquilamino-2.2.8.-trimetil-4h-dioxino-(4,5-c)-piridina.-

Info

Publication number
AR240942A2
AR240942A2 AR30190985A AR30190985A AR240942A2 AR 240942 A2 AR240942 A2 AR 240942A2 AR 30190985 A AR30190985 A AR 30190985A AR 30190985 A AR30190985 A AR 30190985A AR 240942 A2 AR240942 A2 AR 240942A2
Authority
AR
Argentina
Prior art keywords
alkyl
methyl
dioxino
trimethyl
phenethyl
Prior art date
Application number
AR30190985A
Other languages
English (en)
Other versions
AR240942A1 (es
Original Assignee
Sod Conseils Rech Applic
Scient S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic, Scient S filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of AR240942A1 publication Critical patent/AR240942A1/es
Publication of AR240942A2 publication Critical patent/AR240942A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Abstract

UN PROCESO PARA LA PREPARACION DE NUEVOPS DERIVADOS DE 5-(1-CIANO-1-ALQUIL-N-METIL-N-NETOXI-FENETIL)-ALQUILAMINO-2.2.8-TRIMETIL-4H-DIOXINO-(4,5-C)-PIRIDINA DE FORMULA (I), DONDE N ES UN NUMERO ENTERO ENTRE 2 Y 5, R1 REPRESENTA UN ALQUILO Y R2 REPRESENTA DOS TRES OCH3, Y DE SALES TERAPEUTICAMENTE ACEPTABLES PORQUE COMPRENDE EN HACER REACCIONAR, EN PROPORCIONES ESTEQUIOMETRICAS LA CORRESPONDIENTE 5-(1-CIANO-1-R1)-METIL-2,2,8-TRIMETIL-4H-DIOXINO-(4,5-C)PIRIDINA DE FORMULA (II), DONDE R1 ES LO YA DEFINIDOCON EL CLORURO N-METIL-N-(METOXI-FENETIL)-OMEGA-ALQUILO DE FORMULA(III), DONDE N Y R2 SON LAS YA DEFENIDAS EN PRESENCIA DE UNA CANTIDAD ESTEQUIOMETRICA DE HIDRURO DE /SODIO, EN DIMETILSULFOXIDO, A UNA TEMPERATURA COMPRENDIDA ENTRE 15 Y 65 C.
AR301909A 1984-10-23 1985-10-11 Un proceso para la preparacion de nuevos derivados de 5-(1-ciano-1-alquil-n-mentil-n-metoxi-fenetil)-alquilamino-2.2.8.-trimetil-4h-dioxino-(4,5-c)-piridina.- AR240942A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848426738A GB8426738D0 (en) 1984-10-23 1984-10-23 Pyridine derivatives

Publications (2)

Publication Number Publication Date
AR240942A1 AR240942A1 (es) 1991-03-27
AR240942A2 true AR240942A2 (es) 1991-03-27

Family

ID=10568592

Family Applications (1)

Application Number Title Priority Date Filing Date
AR301909A AR240942A1 (es) 1984-10-23 1985-10-11 Un proceso para la preparacion de nuevos derivados de 5-(1-ciano-1-alquil-n-mentil-n-metoxi-fenetil)-alquilamino-2.2.8.-trimetil-4h-dioxino-(4,5-c)-piridina.-

Country Status (26)

Country Link
US (1) US4610990A (es)
JP (1) JPS61106578A (es)
AR (1) AR240942A1 (es)
AT (1) AT393682B (es)
BE (1) BE903403A (es)
CA (1) CA1286300C (es)
CH (1) CH665842A5 (es)
DE (1) DE3537715A1 (es)
DK (1) DK159319C (es)
DZ (1) DZ851A1 (es)
ES (1) ES8609329A1 (es)
FI (1) FI82249C (es)
FR (2) FR2571965B1 (es)
GB (2) GB8426738D0 (es)
HK (1) HK44388A (es)
IE (1) IE58499B1 (es)
IT (1) IT1190409B (es)
LU (1) LU86117A1 (es)
MA (1) MA20559A1 (es)
MY (1) MY102281A (es)
NL (1) NL8502788A (es)
NO (1) NO163777C (es)
OA (1) OA08125A (es)
PT (1) PT81351B (es)
SE (1) SE460904B (es)
ZA (1) ZA857650B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3642331A1 (de) * 1986-12-11 1988-06-23 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel
JPH02102810U (es) * 1989-01-31 1990-08-15
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
JPH02141516U (es) * 1989-04-25 1990-11-28
US5395939A (en) * 1993-11-30 1995-03-07 North Carolina State University Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives

Also Published As

Publication number Publication date
SE460904B (sv) 1989-12-04
FR2572075A1 (fr) 1986-04-25
NO163777B (no) 1990-04-09
HK44388A (en) 1988-06-17
OA08125A (fr) 1987-03-31
NO854206L (no) 1986-04-24
US4610990A (en) 1986-09-09
MA20559A1 (fr) 1986-07-01
GB2165845B (en) 1988-01-06
DE3537715C2 (es) 1992-04-09
ATA305785A (de) 1991-05-15
FR2572075B1 (fr) 1988-10-14
FI854088A0 (fi) 1985-10-21
JPS638114B2 (es) 1988-02-19
NO163777C (no) 1990-07-18
FI82249C (fi) 1991-02-11
AR240942A1 (es) 1991-03-27
JPS61106578A (ja) 1986-05-24
SE8504825D0 (sv) 1985-10-16
FI854088L (fi) 1986-04-24
GB2165845A (en) 1986-04-23
GB8426738D0 (en) 1984-11-28
IE58499B1 (en) 1993-10-06
GB8524709D0 (en) 1985-11-13
IT8522597A0 (it) 1985-10-23
ES8609329A1 (es) 1986-09-01
ZA857650B (en) 1986-05-28
BE903403A (fr) 1986-04-09
PT81351A (en) 1985-11-01
FR2571965B1 (fr) 1990-09-28
DE3537715A1 (de) 1986-04-24
CH665842A5 (fr) 1988-06-15
CA1286300C (en) 1991-07-16
FR2571965A1 (fr) 1986-04-25
DK483185D0 (da) 1985-10-22
MY102281A (en) 1992-05-15
DK159319C (da) 1991-02-25
DZ851A1 (fr) 2004-09-13
ES548108A0 (es) 1986-09-01
DK483185A (da) 1986-04-24
LU86117A1 (fr) 1986-03-24
DK159319B (da) 1990-10-01
IE852609L (en) 1986-04-23
FI82249B (fi) 1990-10-31
SE8504825L (sv) 1986-04-24
IT1190409B (it) 1988-02-16
AT393682B (de) 1991-11-25
NL8502788A (nl) 1986-05-16
PT81351B (pt) 1987-11-11

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