AR241021A2 - Un proceso de preparacion de nuevos derivados de 5-(omega-fenitilamialquil)-4,5,6,7-tetrahidro-tieno-(3, 2-c)-piridina" - Google Patents

Un proceso de preparacion de nuevos derivados de 5-(omega-fenitilamialquil)-4,5,6,7-tetrahidro-tieno-(3, 2-c)-piridina"

Info

Publication number
AR241021A2
AR241021A2 AR30210985A AR30210985A AR241021A2 AR 241021 A2 AR241021 A2 AR 241021A2 AR 30210985 A AR30210985 A AR 30210985A AR 30210985 A AR30210985 A AR 30210985A AR 241021 A2 AR241021 A2 AR 241021A2
Authority
AR
Argentina
Prior art keywords
group
same
formula
compositions containing
tieno
Prior art date
Application number
AR30210985A
Other languages
English (en)
Other versions
AR241021A1 (es
Original Assignee
Sod Conseils Rech Applic
Scient S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic, Scient S filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of AR241021A2 publication Critical patent/AR241021A2/es
Publication of AR241021A1 publication Critical patent/AR241021A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE NUEVOS DERIVADOS DE 5-(OMEGA-FENETILAMINO-ALQUIL)-4,5,6, 7-TETRAHIDRO-TIENO-(3,2-C)-PIRIDINA DE FORMULA (I) DONDE N ES UN ENTERO COMPRENDIDO ENTRE2 Y 5, R1 REPRESENTA UN ATOMO DE H O UN GRUPO 3,4-DIMETOXIFENILO, R2 REPRESENTA UN ATOMO DE H UN GRUPO ALQUILO O UN GRUPO 4-CIANO-4-(3, 4-DIMETOXIFENIL)- 5-METILHEXIL Y R3 REPRESENTA DOS O TRES GRUPOS METOXI, Y DE SUS SALES TERAPEUTICAMENTE ACEPTABLES.EL PROCESO COMPRENDE CONDENSAR UNA 5-(OMEGA-CLOROALQUIL)-4,5,6,7-TETRAHIDRO-TIENO- (3,2-C)-PIRIDINA DE FORMULA II DONDE N Y R1 SON LOS DEFINIDOS MAS ARRIBA CON UN DERIVADO FENETILAMINA DE FORMULA III, DONDE R2 YR3 SON LOS DEFINIDOS MAS ARRIBA, A UNA TEMPERATURA COMPRENDIDA ENTRE 90 Y 130 C BAJO CIRCULACION DE NITROGENO.
AR302109A 1984-11-16 1985-10-29 Un proceso de preparacion de nuevos derivados de 5-(omega-fenitilamialquil)-4,5,6,7-tetrahidro-tieno-(3,2-c)-piridina" AR241021A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848429087A GB8429087D0 (en) 1984-11-16 1984-11-16 Thienopyridine derivatives

Publications (2)

Publication Number Publication Date
AR241021A2 true AR241021A2 (es) 1991-04-30
AR241021A1 AR241021A1 (es) 1991-04-30

Family

ID=10569875

Family Applications (1)

Application Number Title Priority Date Filing Date
AR302109A AR241021A1 (es) 1984-11-16 1985-10-29 Un proceso de preparacion de nuevos derivados de 5-(omega-fenitilamialquil)-4,5,6,7-tetrahidro-tieno-(3,2-c)-piridina"

Country Status (25)

Country Link
US (1) US4681888A (es)
JP (1) JPH06785B2 (es)
AR (1) AR241021A1 (es)
AT (1) AT394559B (es)
BE (1) BE903499A (es)
CA (1) CA1292233C (es)
CH (1) CH665211A5 (es)
DE (1) DE3540529A1 (es)
DK (1) DK158738C (es)
DZ (1) DZ860A1 (es)
ES (1) ES8701762A1 (es)
FI (1) FI81352C (es)
FR (2) FR2573429B1 (es)
GB (1) GB8429087D0 (es)
HK (1) HK10389A (es)
IE (1) IE58591B1 (es)
IT (1) IT1201497B (es)
LU (1) LU86137A1 (es)
MA (1) MA20567A1 (es)
NL (1) NL8502946A (es)
NO (1) NO162072C (es)
OA (1) OA08172A (es)
PT (1) PT81487B (es)
SE (1) SE453505B (es)
ZA (1) ZA858267B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294621A (en) * 1992-10-07 1994-03-15 Ortho Pharmaceutical Corporation Thieno tetrahydropyridines useful as class III antiarrhythmic agents
US6177443B1 (en) 1997-03-07 2001-01-23 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use
JP2001514631A (ja) * 1997-03-07 2001-09-11 ノボ ノルディスク アクティーゼルスカブ ４，５，６，７−テトラヒドロ−チエノ［３，２−ｃ］ピリジン誘導体類、それらの製造方法及び使用
CN102241690B (zh) 2010-05-13 2015-08-12 天津药物研究院 一类含腈基的噻吩并吡啶酯类衍生物、其制备方法和用途
CN101863898B (zh) * 2010-05-26 2011-09-07 天津药物研究院 含哌嗪的噻吩并吡啶酮类衍生物、其制备方法和用途
CN101805355B (zh) * 2010-05-27 2012-07-04 天津药物研究院 一类噻吩并吡啶酮衍生物、其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948B1 (es) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
DE2658500C2 (de) * 1976-12-23 1986-10-09 Knoll Ag, 6700 Ludwigshafen Pharmazeutische Präparate mit kardioprotektiver Wirkung
GB1576511A (en) * 1977-03-29 1980-10-08 Parcor Thieno(2,3 - c) and (3,2 - c) pyridines process for their preparation and therapeutic applications thereof
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique

Also Published As

Publication number Publication date
IE58591B1 (en) 1993-10-20
BE903499A (fr) 1986-04-22
SE8505369D0 (sv) 1985-11-13
ZA858267B (en) 1986-06-25
NO854577L (no) 1986-05-20
ES8701762A1 (es) 1986-12-01
MA20567A1 (fr) 1986-07-01
FI854298A0 (fi) 1985-11-01
HK10389A (en) 1989-02-10
NO162072C (no) 1989-11-01
GB8429087D0 (en) 1984-12-27
FR2573429B1 (fr) 1988-11-25
IT1201497B (it) 1989-02-02
FR2573309B1 (fr) 1988-11-25
SE8505369L (sv) 1986-05-17
IE852866L (en) 1986-05-16
DE3540529C2 (es) 1992-04-30
AT394559B (de) 1992-05-11
NO162072B (no) 1989-07-24
US4681888A (en) 1987-07-21
CA1292233C (en) 1991-11-19
FR2573429A1 (fr) 1986-05-23
DK158738C (da) 1990-11-26
FI854298A (fi) 1986-05-17
FI81352C (fi) 1990-10-10
CH665211A5 (fr) 1988-04-29
OA08172A (fr) 1987-03-31
AR241021A1 (es) 1991-04-30
IT8522868A0 (it) 1985-11-15
DK527685D0 (da) 1985-11-15
PT81487A (en) 1985-12-01
DZ860A1 (fr) 2004-09-13
DE3540529A1 (de) 1986-05-22
ATA335685A (de) 1991-10-15
DK158738B (da) 1990-07-09
FR2573309A1 (fr) 1986-05-23
JPS61122288A (ja) 1986-06-10
SE453505B (sv) 1988-02-08
DK527685A (da) 1986-05-17
NL8502946A (nl) 1986-06-16
PT81487B (pt) 1987-12-30
FI81352B (fi) 1990-06-29
ES548925A0 (es) 1986-12-01
JPH06785B2 (ja) 1994-01-05
LU86137A1 (fr) 1986-03-24

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