BE897843A - Derives biologiquement actifs de 2, 5-piperazinediones, procede pour leur preparation et compositions pharmaceutique en contenant - Google Patents

Derives biologiquement actifs de 2, 5-piperazinediones, procede pour leur preparation et compositions pharmaceutique en contenant Download PDF

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Publication number
BE897843A
BE897843A BE0/211589A BE211589A BE897843A BE 897843 A BE897843 A BE 897843A BE 0/211589 A BE0/211589 A BE 0/211589A BE 211589 A BE211589 A BE 211589A BE 897843 A BE897843 A BE 897843A
Authority
BE
Belgium
Prior art keywords
amino
cyclo
formula
carbonyl
compound
Prior art date
Application number
BE0/211589A
Other languages
English (en)
French (fr)
Inventor
E Kasafirek
J Vanzura
I Krejci
J Krepelka
A Dlabac
M Valchar
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of BE897843A publication Critical patent/BE897843A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE0/211589A 1982-10-01 1983-09-27 Derives biologiquement actifs de 2, 5-piperazinediones, procede pour leur preparation et compositions pharmaceutique en contenant BE897843A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS827012A CS231227B1 (en) 1982-10-01 1982-10-01 2,5-pierazindion derivatives

Publications (1)

Publication Number Publication Date
BE897843A true BE897843A (fr) 1984-01-16

Family

ID=5418454

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/211589A BE897843A (fr) 1982-10-01 1983-09-27 Derives biologiquement actifs de 2, 5-piperazinediones, procede pour leur preparation et compositions pharmaceutique en contenant

Country Status (12)

Country Link
JP (1) JPS5989671A (de)
AT (1) AT388161B (de)
BE (1) BE897843A (de)
CH (1) CH655929A5 (de)
CS (1) CS231227B1 (de)
DE (1) DE3335891C2 (de)
FR (1) FR2533919B1 (de)
GB (1) GB2127807B (de)
HU (1) HU193047B (de)
IT (1) IT1171091B (de)
SE (1) SE466654B (de)
YU (1) YU44751B (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999040931A1 (en) * 1998-02-11 1999-08-19 Georgetown University Cyclic dipeptides and azetidinone compounds and their use in treating cns injury and neurodegenerative disorders
WO2013020527A1 (en) 2011-08-11 2013-02-14 University Of Veterinary And Pharmaceutical Sciences Brno Faculty Of Pharmacy Utilization of alaptide as transdermal penetration modifier in pharmaceutical compositions for human and veterinary applications containing anti-inflammatory drugs and/or antimicrobial chemotherapeutics
WO2014019556A1 (en) 2012-08-02 2014-02-06 University Of Veterinary And Pharmaceutical Sciences Brno Faculty Of Pharmacy Alaptide : methods of effecting its solubility, membrane permeation and pharmaceutical compositions for human and/or veterinary applications

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS277405B6 (en) * 1986-06-12 1993-03-17 Vyzk Ustav Farm Biochem Sp Peptides with 1-amino-1-cycloalkane carboxylic acid
US5182285A (en) * 1986-11-07 1993-01-26 Spojene Podniky Pro Zdravotnickou Vyrobu Cell-protective composition for preventing or treating of peptic ulcer
GB8822674D0 (en) * 1988-09-27 1988-11-02 Tate & Lyle Plc Preparation of acylated sucrose derivatives
JP4721087B2 (ja) 1999-12-03 2011-07-13 小野薬品工業株式会社 トリアザスピロ［５．５］ウンデカン誘導体およびそれらを有効成分とする薬剤
WO2002074769A1 (fr) * 2001-03-19 2002-09-26 Ono Pharmaceutical Co., Ltd. Medicaments contenant comme principe actif des derives du triazaspiro [5.5] undecane
JP4047365B2 (ja) 2006-01-11 2008-02-13 生化学工業株式会社 シクロアルカンカルボキサミド誘導体及びその製造方法
WO2007080884A1 (ja) * 2006-01-11 2007-07-19 Seikagaku Corporation シクロアルキルカルボニルアミノ酸エステル誘導体及びその製造方法
JP3975226B2 (ja) 2006-01-11 2007-09-12 生化学工業株式会社 シクロアルキルカルボニルアミノ酸誘導体及びその製造方法
CN107903303B (zh) * 2017-11-20 2021-06-04 陕西慧康生物科技有限责任公司 一种环肽Alaptide的液相合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1459488A (en) * 1974-03-19 1976-12-22 Wyeth John & Brother Ltd Piperazinedione derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999040931A1 (en) * 1998-02-11 1999-08-19 Georgetown University Cyclic dipeptides and azetidinone compounds and their use in treating cns injury and neurodegenerative disorders
WO2013020527A1 (en) 2011-08-11 2013-02-14 University Of Veterinary And Pharmaceutical Sciences Brno Faculty Of Pharmacy Utilization of alaptide as transdermal penetration modifier in pharmaceutical compositions for human and veterinary applications containing anti-inflammatory drugs and/or antimicrobial chemotherapeutics
WO2014019556A1 (en) 2012-08-02 2014-02-06 University Of Veterinary And Pharmaceutical Sciences Brno Faculty Of Pharmacy Alaptide : methods of effecting its solubility, membrane permeation and pharmaceutical compositions for human and/or veterinary applications

Also Published As

Publication number Publication date
JPH0526782B2 (de) 1993-04-19
CS701282A1 (en) 1984-01-16
DE3335891A1 (de) 1984-04-05
YU44751B (en) 1991-02-28
SE8305157L (sv) 1984-04-02
YU195283A (en) 1986-10-31
FR2533919B1 (fr) 1986-10-03
GB2127807B (en) 1987-02-25
IT8323058A0 (it) 1983-09-29
AT388161B (de) 1989-05-10
GB8324683D0 (en) 1983-10-19
SE8305157D0 (sv) 1983-09-23
FR2533919A1 (fr) 1984-04-06
ATA336683A (de) 1988-10-15
CS231227B1 (en) 1984-10-15
IT8323058A1 (it) 1985-03-29
JPS5989671A (ja) 1984-05-23
SE466654B (sv) 1992-03-16
CH655929A5 (de) 1986-05-30
HU193047B (en) 1987-08-28
GB2127807A (en) 1984-04-18
IT1171091B (it) 1987-06-10
DE3335891C2 (de) 1993-11-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SPOFA SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU

Effective date: 19970930