BE884716A - Derives du 1,1,2-triphenylpropane et du 1,1,2-triphenylpropene procede de preparation de ces derives et compositions pharmaceutiques contenant ces nouveaux composes - Google Patents

Derives du 1,1,2-triphenylpropane et du 1,1,2-triphenylpropene procede de preparation de ces derives et compositions pharmaceutiques contenant ces nouveaux composes

Info

Publication number
BE884716A
BE884716A BE1/9927A BE1009927A BE884716A BE 884716 A BE884716 A BE 884716A BE 1/9927 A BE1/9927 A BE 1/9927A BE 1009927 A BE1009927 A BE 1009927A BE 884716 A BE884716 A BE 884716A
Authority
BE
Belgium
Prior art keywords
derivatives
triphenylpropene
triphenylpropane
preparation
pharmaceutical compositions
Prior art date
Application number
BE1/9927A
Other languages
English (en)
French (fr)
Original Assignee
Gyogyszerki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerki filed Critical Gyogyszerki
Publication of BE884716A publication Critical patent/BE884716A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2635—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving a phosphorus compound, e.g. Wittig synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C07C17/354—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction by hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/003—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by hydrogenation of an unsaturated part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B22/00—Buoys
    • B63B2022/006—Buoys specially adapted for measuring or watch purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B2211/00—Applications
    • B63B2211/02—Oceanography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
BE1/9927A 1979-08-15 1980-08-11 Derives du 1,1,2-triphenylpropane et du 1,1,2-triphenylpropene procede de preparation de ces derives et compositions pharmaceutiques contenant ces nouveaux composes BE884716A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79GO1455A HU178253B (en) 1979-08-15 1979-08-15 Process for preparing 1,1,2-triphenyl-propane and -propane derivatives

Publications (1)

Publication Number Publication Date
BE884716A true BE884716A (fr) 1981-02-11

Family

ID=10996899

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/9927A BE884716A (fr) 1979-08-15 1980-08-11 Derives du 1,1,2-triphenylpropane et du 1,1,2-triphenylpropene procede de preparation de ces derives et compositions pharmaceutiques contenant ces nouveaux composes

Country Status (22)

Country Link
JP (1) JPS5668637A (OSRAM)
AT (1) AT372074B (OSRAM)
BE (1) BE884716A (OSRAM)
BG (3) BG35031A3 (OSRAM)
CA (1) CA1179359A (OSRAM)
CH (1) CH649758A5 (OSRAM)
CS (1) CS241030B2 (OSRAM)
DD (1) DD152536A5 (OSRAM)
DE (1) DE3030802A1 (OSRAM)
DK (1) DK351780A (OSRAM)
ES (1) ES494286A0 (OSRAM)
FI (1) FI74271C (OSRAM)
FR (1) FR2463121B1 (OSRAM)
GB (1) GB2058061B (OSRAM)
GR (1) GR69821B (OSRAM)
HU (1) HU178253B (OSRAM)
IT (1) IT1228130B (OSRAM)
NL (1) NL8004542A (OSRAM)
PL (3) PL131226B1 (OSRAM)
SE (1) SE450250B (OSRAM)
SU (3) SU1253426A1 (OSRAM)
YU (2) YU42980B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0175188A1 (de) * 1984-09-11 1986-03-26 Nihon Tokushu Noyaku Seizo K.K. Carbamoylimidazol-Derivate
US5681835A (en) * 1994-04-25 1997-10-28 Glaxo Wellcome Inc. Non-steroidal ligands for the estrogen receptor
AU3879095A (en) * 1994-11-02 1996-05-31 Egis Gyogyszergyar Rt. Process and intermediates for preparing triphenyltrifluoropropanes and -propenes
HUP0002852A3 (en) 1997-08-15 2001-11-28 Univ Durham A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives
CN1061334C (zh) * 1998-06-02 2001-01-31 中国科学院上海有机化学研究所 不饱和键三氟乙基化化合物的制备方法
US7935697B2 (en) * 2006-12-28 2011-05-03 Kinex Pharmaceuticals, Llc Compositions for modulating a kinase cascade and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (OSRAM) * 1962-09-13
US3712929A (en) * 1969-10-31 1973-01-23 Du Pont 1-perfluoroalkyl-1,2,2-triphenylethylenes

Also Published As

Publication number Publication date
ATA419280A (de) 1983-01-15
CH649758A5 (de) 1985-06-14
SU1253426A3 (ru) 1986-08-23
PL131227B1 (en) 1984-10-31
SE8005688L (sv) 1981-02-16
CA1179359A (en) 1984-12-11
YU42980B (en) 1989-02-28
CS561680A2 (en) 1985-06-13
BG35031A3 (bg) 1984-01-16
NL8004542A (nl) 1981-02-17
FI74271B (fi) 1987-09-30
GB2058061B (en) 1983-07-20
DE3030802A1 (de) 1981-03-12
YU43182B (en) 1989-04-30
FI74271C (fi) 1988-01-11
DK351780A (da) 1981-02-16
BG34903A3 (bg) 1983-12-15
SU1097192A3 (ru) 1984-06-07
JPS5668637A (en) 1981-06-09
SU1114332A3 (ru) 1984-09-15
CS241030B2 (en) 1986-03-13
DD152536A5 (de) 1981-12-02
YU206880A (en) 1983-12-31
PL131226B1 (en) 1984-10-31
PL130386B1 (en) 1984-08-31
ES8104782A1 (es) 1981-04-16
FR2463121B1 (fr) 1987-01-02
IT1228130B (it) 1991-05-28
BG35032A3 (bg) 1984-01-16
SE450250B (sv) 1987-06-15
PL238085A1 (en) 1983-04-11
DE3030802C2 (OSRAM) 1987-06-04
JPH0234933B2 (OSRAM) 1990-08-07
GB2058061A (en) 1981-04-08
IT8024152A0 (it) 1980-08-14
FI802584A7 (fi) 1981-02-16
SU1253426A1 (ru) 1986-08-23
ES494286A0 (es) 1981-04-16
PL226254A1 (en) 1983-01-17
HU178253B (en) 1982-04-28
YU123983A (en) 1986-04-30
FR2463121A1 (fr) 1981-02-20
GR69821B (OSRAM) 1982-07-13
AT372074B (de) 1983-08-25

Similar Documents

Publication Publication Date Title
FR2511005B1 (fr) Procede de preparation de derives d'esters internes de gangliosides et compositions pharmaceutiques contenant ces derives
FR2466248B1 (fr) Derives d'agents anti-inflammatoires non steroides, procede de preparation et compositions pharmaceutiques les contenant
PT78340A (fr) Procede de preparation de nouveaux derives de la tetrahydroxy- 3',4',5,7-flavone et des compositions pharmaceutiques les contenant
BE868796A (fr) Nouveaux derives de 1-acyl 2-cyano-aziridine, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
PT85279A (fr) Procede de preparation de derives du nitrofurane et de compositions pharmaceutiques les contenant
LU78330A1 (fr) Procede de preparation de nouveaux derives d'hydantoine et de composition pharmaceutique les contenant
BE885385A (fr) Derives de d-6-n-propylergolines, leur procede de preparation et compositions pharmaceutiques en contenant
BE892552A (fr) Nouveaux amido-aminoacides, compositions pharmaceutiques les contenant et procede de preparation de ces amido-aminoacides
BE857138A (fr) Derives peptidiques, procede pour leur preparation et compositions therapeutiques contenant ces composes
BE862870A (fr) Nouveaux derives steroides 11 beta-substitues 1,3,5(10)-trieniques, procede de preparation et compositions pharmaceutiques
BE864173A (fr) Nouveaux derives de 20,21-dinoreburnamenine, procede de preparation et compositions pharmaceutiques
PT82364A (fr) Procede de preparation de derives du nitrofuranne et de compositions pharmaceutiques les contenant
FR2463121B1 (fr) Derives du 1,1,2-triphenylpropane et du 1,1,2-triphenylpropene, procede de preparation de ces derives et compositions pharmaceutiques contenant ces nouveaux composes
BE885633A (fr) Derives de 1,2,4-oxadiazolin-5-one, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2529551B1 (fr) Derives d'eburnane-oxime, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
PT77751A (fr) Procede de preparation de derives benzylideniques soufres et de compositions pharmaceutiques le contenant
BE826711A (fr) Derives d'indolylacetylamino-acide, leur procede de preparation et les compositions pharmaceutiques contenant ces composes
FR2528422B1 (fr) Nouveaux derives du 1,2,3,4-tetrahydronaphtalene, procede pour leur preparation et composition pharmaceutique contenant ces derives
BE877658A (fr) Nouveaux derives acetyleniques de l'androst-4-ene, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
PT70005A (fr) Procede de preparation de nouveaux derives de 6-methoxy-2-acetylnaphtalene oxime et des compositions pharmaceutiquesles contenant
BE875091A (fr) Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
PT75868A (fr) Procede de preparation de derives benzylideniques et de compositions pharmaceutiques les contenant
PT74952A (fr) Procede de preparation de derives heterocycliques d'amidoximes et de compositions pharmaceutiques les contenant
PT70107A (fr) Procede de preparation de nouveaux derives de 1,3-benzoxazine-2,4-dione et des compositions pharmaceutiques les contenant
BE884473A (fr) Nouveaux derives de nitroalcanols, procede pour leur preparation, et compositions, contenant de telles substances, utilisables pour la protection de plantes

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: EGYT GYOGYSZERVE GYESZETI GYAR

Effective date: 19970831