BE867727A - Nouveaux composes de phtalazine et composition pharmaceutique les contenant - Google Patents

Nouveaux composes de phtalazine et composition pharmaceutique les contenant

Info

Publication number
BE867727A
BE867727A BE188257A BE188257A BE867727A BE 867727 A BE867727 A BE 867727A BE 188257 A BE188257 A BE 188257A BE 188257 A BE188257 A BE 188257A BE 867727 A BE867727 A BE 867727A
Authority
BE
Belgium
Prior art keywords
phtalazine
compounds
new
pharmaceutical composition
composition containing
Prior art date
Application number
BE188257A
Other languages
English (en)
French (fr)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE867727A publication Critical patent/BE867727A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE188257A 1977-06-03 1978-06-01 Nouveaux composes de phtalazine et composition pharmaceutique les contenant BE867727A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (1)

Publication Number Publication Date
BE867727A true BE867727A (fr) 1978-12-01

Family

ID=10198020

Family Applications (1)

Application Number Title Priority Date Filing Date
BE188257A BE867727A (fr) 1977-06-03 1978-06-01 Nouveaux composes de phtalazine et composition pharmaceutique les contenant

Country Status (29)

Country Link
US (1) US4289772A (pt)
JP (1) JPS5416488A (pt)
AR (2) AR222013A1 (pt)
AT (2) AT362792B (pt)
AU (1) AU505373B1 (pt)
BE (1) BE867727A (pt)
CA (1) CA1111850A (pt)
DD (1) DD137355A5 (pt)
DE (1) DE2824064A1 (pt)
DK (1) DK248078A (pt)
EG (1) EG13527A (pt)
ES (4) ES470470A1 (pt)
FI (1) FI781753A (pt)
FR (1) FR2392986A1 (pt)
GB (1) GB2000136B (pt)
GR (1) GR74402B (pt)
HU (1) HU179745B (pt)
IL (1) IL54842A (pt)
IN (3) IN148482B (pt)
IT (1) IT1094944B (pt)
LU (1) LU79761A1 (pt)
NL (1) NL7806016A (pt)
NO (1) NO781935L (pt)
NZ (1) NZ187453A (pt)
PL (3) PL116437B1 (pt)
PT (1) PT68126A (pt)
SE (1) SE7806519L (pt)
SU (2) SU856383A3 (pt)
ZA (1) ZA783183B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
PH17019A (en) * 1980-03-01 1984-05-11 Wyeth John & Brother Ltd 4-piperidyl-or dehydropiperidyl-urea derivatives and method of use
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
US5728712A (en) * 1995-05-19 1998-03-17 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
AU722710B2 (en) * 1996-08-20 2000-08-10 Eisai Co. Ltd. Remedies for erectile dysfunction containing fused pyridazine compounds
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
DK1539739T3 (da) * 2002-08-16 2011-03-07 Janssen Pharmaceutica Nv Piperidinylforbindelser, der selektivt binder integriner
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス,インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
JP2009524637A (ja) * 2006-01-27 2009-07-02 ファイザー・プロダクツ・インク アミノフタラジン誘導体化合物
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007110449A1 (en) 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
WO2007118853A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and their use as blockers of calcium channels
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
KR101167774B1 (ko) 2007-08-07 2012-07-24 에프. 호프만-라 로슈 아게 Nk3 수용체 길항제로서의 피롤리딘 아릴-에터
RU2010108687A (ru) 2007-08-22 2011-09-27 Ф.Хоффманн-Ля Рош Аг (Ch) Ариловые эфиры пирролидина в качестве антагонистов рецепторов nk3
CA2699464A1 (en) * 2007-09-14 2009-03-19 F. Hoffmann-La Roche Ag Piperidine derivatives as nk3 receptor antagonists
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
GR74402B (pt) 1984-06-28
PT68126A (en) 1978-07-01
AT362792B (de) 1981-06-10
GB2000136B (en) 1982-01-06
IT1094944B (it) 1985-08-10
ES478201A1 (es) 1980-02-01
SU856383A3 (ru) 1981-08-15
PL113208B1 (en) 1980-11-29
IT7824106A0 (it) 1978-06-01
GB2000136A (en) 1979-01-04
NO781935L (no) 1978-12-05
DD137355A5 (de) 1979-08-29
EG13527A (en) 1981-12-31
CA1111850A (en) 1981-11-03
NL7806016A (nl) 1978-12-05
LU79761A1 (fr) 1980-01-22
FR2392986B1 (pt) 1982-07-16
PL116420B1 (en) 1981-06-30
AU505373B1 (en) 1979-11-15
AR223999A1 (es) 1981-10-15
IL54842A (en) 1982-01-31
ES478200A1 (es) 1980-01-01
PL116437B1 (en) 1981-06-30
FR2392986A1 (fr) 1978-12-29
DE2824064A1 (de) 1978-12-14
ATA400878A (de) 1980-11-15
ATA305080A (de) 1980-12-15
IN148482B (pt) 1981-03-07
SU862826A3 (ru) 1981-09-07
ES478199A1 (es) 1980-01-16
US4289772A (en) 1981-09-15
FI781753A (fi) 1978-12-04
IL54842A0 (en) 1978-08-31
JPS5538351B2 (pt) 1980-10-03
SE7806519L (sv) 1978-12-04
JPS5416488A (en) 1979-02-07
IN149550B (pt) 1982-01-16
AR222013A1 (es) 1981-04-15
IN149973B (pt) 1982-06-19
HU179745B (en) 1982-12-28
ES470470A1 (es) 1979-09-01
AT363096B (de) 1981-07-10
ZA783183B (en) 1979-06-27
NZ187453A (en) 1980-12-19
DK248078A (da) 1978-12-04
PL207337A1 (pl) 1979-06-04

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