BE2015C015I2 - - Google Patents
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- Publication number
- BE2015C015I2 BE2015C015I2 BE2015C015C BE2015C015C BE2015C015I2 BE 2015C015 I2 BE2015C015 I2 BE 2015C015I2 BE 2015C015 C BE2015C015 C BE 2015C015C BE 2015C015 C BE2015C015 C BE 2015C015C BE 2015C015 I2 BE2015C015 I2 BE 2015C015I2
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/02—Monocyclic hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
- A61K31/115—Formaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63669604P | 2004-12-17 | 2004-12-17 | |
| US68639505P | 2005-06-02 | 2005-06-02 | |
| EP05854410A EP1841465A4 (en) | 2004-12-17 | 2005-12-19 | STYLENE DERIVATIVES AND THEIR USE OF THE BINDING AND IMAGE DISPLAY OF AMYLOID PLAQUE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE2015C015I2 true BE2015C015I2 (OSRAM) | 2025-04-29 |
Family
ID=36588603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2015C015C BE2015C015I2 (OSRAM) | 2004-12-17 | 2015-03-10 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US7807135B2 (OSRAM) |
| EP (3) | EP1841465A4 (OSRAM) |
| JP (1) | JP5128956B2 (OSRAM) |
| KR (1) | KR101321619B1 (OSRAM) |
| AU (1) | AU2005316421B2 (OSRAM) |
| BE (1) | BE2015C015I2 (OSRAM) |
| BR (1) | BRPI0516408B8 (OSRAM) |
| CA (1) | CA2591534C (OSRAM) |
| DK (1) | DK2213652T3 (OSRAM) |
| EA (1) | EA012334B1 (OSRAM) |
| ES (1) | ES2526655T3 (OSRAM) |
| FR (1) | FR15C0012I2 (OSRAM) |
| HU (1) | HUS1500014I1 (OSRAM) |
| IL (2) | IL183946A (OSRAM) |
| LT (1) | LTC2213652I2 (OSRAM) |
| LU (1) | LU92647I2 (OSRAM) |
| MX (1) | MX2007007380A (OSRAM) |
| NL (1) | NL300719I1 (OSRAM) |
| NO (1) | NO339195B1 (OSRAM) |
| NZ (1) | NZ555942A (OSRAM) |
| PL (1) | PL2213652T3 (OSRAM) |
| PT (1) | PT2213652E (OSRAM) |
| SG (1) | SG194363A1 (OSRAM) |
| SI (1) | SI2213652T1 (OSRAM) |
| WO (1) | WO2006066104A2 (OSRAM) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1432453T3 (da) * | 2001-08-27 | 2013-11-18 | Univ Pennsylvania | Stilbenderivater og anvendelse heraf til binding og billeddannelse af amyloid-plaques |
| US7858072B2 (en) * | 2004-12-17 | 2010-12-28 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| EP1841465A4 (en) * | 2004-12-17 | 2009-04-01 | Univ Pennsylvania | STYLENE DERIVATIVES AND THEIR USE OF THE BINDING AND IMAGE DISPLAY OF AMYLOID PLAQUE |
| CA2617319A1 (en) * | 2005-06-24 | 2007-01-04 | The Trustees Of The University Of Pennsylvania | Radiolabeled-pegylation of ligands for use as imaging agents |
| EP2363392B1 (en) | 2006-03-30 | 2017-05-03 | The Trustees Of The University Of Pennsylvania | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques |
| US20080253967A1 (en) * | 2007-04-13 | 2008-10-16 | Kung Hank F | Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques |
| WO2009001046A2 (en) * | 2007-06-22 | 2008-12-31 | The University Court Of The University Of Aberdeen | [11c]methoxy-radiolabelled 2,3',4,5'-tetramethylstilbene (tms) and its preparation and use |
| EP2172444A4 (en) * | 2007-07-04 | 2010-12-22 | Univ Tohoku | PET PROBE WITH FLUORO-SUBSTITUTED ALKOXY GROUP AND HYDROXYGRUPPE |
| US8779002B2 (en) * | 2007-10-15 | 2014-07-15 | Salk Institute For Biological Studies | Methods for treating a variety of diseases and conditions, and compounds useful therefor |
| US8932557B2 (en) | 2008-02-14 | 2015-01-13 | Eli Lilly And Company | Imaging agents for detecting neurological dysfunction |
| PL2247558T5 (pl) * | 2008-02-14 | 2024-10-14 | Eli Lilly And Company | Nowe środki obrazujące do wykrywania czynnościowych zaburzeń neurologicznych |
| US20100331676A1 (en) * | 2008-02-27 | 2010-12-30 | Avid Radiopharmaceuticals, Inc. | Gamma probe detection of amyloid plaque using radiolabeled a-beta binding compounds |
| US8557222B2 (en) * | 2008-04-04 | 2013-10-15 | Avid Radiopharmaceuticals, Inc. | Radiopharmaceutical imaging of neurodegenerative diseases |
| US20100145194A1 (en) * | 2008-11-13 | 2010-06-10 | Avid Radiopharmaceuticals, Inc. | Histogram-based analysis method for the detection and diagnosis of neurodegenerative diseases |
| EP2379757A2 (en) | 2008-12-22 | 2011-10-26 | Bayer Pharma Aktiengesellschaft | A method for the synthesis of a radionuclide-labeled compound |
| SG172439A1 (en) * | 2008-12-31 | 2011-07-28 | Avid Radiopharmaceuticals Inc | Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof |
| CU23844B1 (es) | 2009-04-17 | 2012-10-15 | Ct De Neurociencias De Cuba | Procedimiento de obtención de nuevos derivados de naftaleno para el diagnóstico in vivo de la enfermedad de alzheimer |
| CA2767475A1 (en) | 2009-07-10 | 2011-01-13 | Bayer Pharma Aktiengesellschaft | Usage of low to medium-pressure liquid chromatography for the purification of radiotracers |
| EA022447B1 (ru) * | 2009-12-23 | 2016-01-29 | Пирамаль Имэджинг Са | Композиции, приемлемые для рет-визуализации при помощи гидрофобных рет-агентов |
| WO2011151283A1 (en) * | 2010-06-04 | 2011-12-08 | Bayer Pharma Aktiengesellschaft | Method for production of f-18 labeled amyloid beta ligands |
| CN103328012A (zh) | 2010-06-04 | 2013-09-25 | 皮拉马影像股份公司 | 生产F-18标记的β-淀粉样蛋白配体的方法 |
| US20130217920A1 (en) | 2010-06-04 | 2013-08-22 | Piramal Imaging Sa | Method for production of f-18 labeled amyloid beta ligands |
| TWI504414B (zh) * | 2010-06-04 | 2015-10-21 | Bayer Schering Pharma Ag | 生產Ｆ－１８標記之Ａβ配位體之方法 |
| US9259495B2 (en) * | 2010-10-12 | 2016-02-16 | Mayo Foundation For Medical Education And Research | Imaging of meningiomas using phenylbenzothiazole, stilbene, or biphenylalkyne derivatives |
| EP3345545B1 (en) | 2011-04-21 | 2021-10-20 | The Regents of The University of California | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles |
| ES2683818T3 (es) * | 2011-06-21 | 2018-09-28 | Piramal Imaging Sa | Formulaciones de estilbeno fluorado aceptables para la formación de imágenes mediante PET |
| KR101291037B1 (ko) * | 2011-10-12 | 2013-08-01 | 사회복지법인 삼성생명공익재단 | 레스베라트롤 유도체와 스티릴-오각형 방향족 화합물 및 이들의 베타-아밀로이드 플라그에 대한 결합제 및 진단영상제의 용도 |
| RU2477726C1 (ru) * | 2011-10-18 | 2013-03-20 | Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") | Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение |
| MX2014004274A (es) | 2011-10-19 | 2014-07-09 | Piramal Imaging Sa | METODO MEJORADO PARA LA PRODUCCION DE LIGANDOS Aß MARCADOS CON F-18. |
| WO2013173004A2 (en) | 2012-04-10 | 2013-11-21 | Lantheus Medical Imaging, Inc. | Radiopharmaceutical synthesis methods |
| US9180212B2 (en) * | 2012-05-22 | 2015-11-10 | The Regents Of The University Of California | β-amyloid plaque imaging agents |
| CU20130027A7 (es) | 2013-02-28 | 2014-10-30 | Ct De Neurociencias De Cuba | Chaperoninas químicas como nuevos moduladores moleculares de la beta agregación proteica presente en las enfermedades conformacionales |
| JP6041751B2 (ja) * | 2013-05-07 | 2016-12-14 | 日本メジフィジックス株式会社 | スチリルピリジン誘導体化合物 |
| JP2014218454A (ja) * | 2013-05-07 | 2014-11-20 | 日本メジフィジックス株式会社 | スチリルピリジン誘導体化合物 |
| KR101891404B1 (ko) * | 2015-12-18 | 2018-08-24 | 주식회사 엘지화학 | 변성 단량체, 이를 포함하는 변성 중합체 및 이들의 제조방법 |
| US10675365B2 (en) | 2016-09-29 | 2020-06-09 | Korea Atomic Energy Research Institute | Curcumin derivative, method for producing same, and photo-acoustic imaging agent comprising same for detecting beta-amyloid plaque |
| JOP20190077A1 (ar) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500507A (en) * | 1981-10-30 | 1985-02-19 | Wong Dennis W | Diagnostic composition for radiologic imaging of neoplasms in the body and method of preparation |
| JPS60247244A (ja) | 1984-05-22 | 1985-12-06 | Mitsubishi Paper Mills Ltd | 電子写真感光体 |
| DD234666A1 (de) | 1984-11-01 | 1986-04-09 | Univ Leipzig | Verfahren zur herstellung von einfachen und substituierten 4-dimethylamino-alpha-halogenstilbenen |
| DD231432A1 (de) * | 1984-11-01 | 1985-12-24 | Univ Leipzig | Material zur silberfreien bildaufzeichnung |
| JPH06329566A (ja) | 1993-05-21 | 1994-11-29 | Asahi Glass Co Ltd | ジフルオロスチルベン誘導体化合物およびそれを含有する液晶組成物 |
| TW325458B (en) | 1993-09-08 | 1998-01-21 | Ajinomoto Kk | Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer |
| US5601801A (en) | 1994-08-02 | 1997-02-11 | Merck Frosst Canada, Inc. | Radiolabelled angiotensin converting enzyme inhibitors |
| US5521213A (en) * | 1994-08-29 | 1996-05-28 | Merck Frosst Canada, Inc. | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
| JP4022951B2 (ja) | 1997-08-06 | 2007-12-19 | 大日本インキ化学工業株式会社 | ジフルオロスチルベン誘導体の製造方法 |
| WO2001084937A1 (en) * | 2000-05-08 | 2001-11-15 | Novozymes A/S | Oxidoreductase mediated antimicrobial activity |
| DK1432453T3 (da) * | 2001-08-27 | 2013-11-18 | Univ Pennsylvania | Stilbenderivater og anvendelse heraf til binding og billeddannelse af amyloid-plaques |
| KR100789847B1 (ko) * | 2004-12-15 | 2007-12-28 | (주)퓨쳐켐 | 알코올 용매하에서 유기플루오로 화합물의 제조방법 |
| US7858072B2 (en) | 2004-12-17 | 2010-12-28 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| EP1841465A4 (en) * | 2004-12-17 | 2009-04-01 | Univ Pennsylvania | STYLENE DERIVATIVES AND THEIR USE OF THE BINDING AND IMAGE DISPLAY OF AMYLOID PLAQUE |
| CA2617319A1 (en) * | 2005-06-24 | 2007-01-04 | The Trustees Of The University Of Pennsylvania | Radiolabeled-pegylation of ligands for use as imaging agents |
-
2005
- 2005-12-19 EP EP05854410A patent/EP1841465A4/en not_active Withdrawn
- 2005-12-19 MX MX2007007380A patent/MX2007007380A/es active IP Right Grant
- 2005-12-19 EP EP10161604.3A patent/EP2213652B1/en not_active Expired - Lifetime
- 2005-12-19 ES ES10161604.3T patent/ES2526655T3/es not_active Expired - Lifetime
- 2005-12-19 WO PCT/US2005/045682 patent/WO2006066104A2/en not_active Ceased
- 2005-12-19 BR BRPI0516408A patent/BRPI0516408B8/pt active IP Right Grant
- 2005-12-19 SI SI200531929T patent/SI2213652T1/sl unknown
- 2005-12-19 EP EP05857100A patent/EP1838298A4/en not_active Withdrawn
- 2005-12-19 EA EA200701299A patent/EA012334B1/ru not_active IP Right Cessation
- 2005-12-19 SG SG2013070958A patent/SG194363A1/en unknown
- 2005-12-19 PT PT101616043T patent/PT2213652E/pt unknown
- 2005-12-19 AU AU2005316421A patent/AU2005316421B2/en not_active Expired
- 2005-12-19 JP JP2007546948A patent/JP5128956B2/ja not_active Expired - Lifetime
- 2005-12-19 NZ NZ555942A patent/NZ555942A/en not_active IP Right Cessation
- 2005-12-19 PL PL10161604T patent/PL2213652T3/pl unknown
- 2005-12-19 KR KR1020077016290A patent/KR101321619B1/ko not_active Expired - Lifetime
- 2005-12-19 US US11/305,333 patent/US7807135B2/en active Active
- 2005-12-19 CA CA2591534A patent/CA2591534C/en not_active Expired - Lifetime
- 2005-12-19 DK DK10161604.3T patent/DK2213652T3/en active
-
2007
- 2007-06-14 IL IL183946A patent/IL183946A/en active IP Right Grant
- 2007-07-16 NO NO20073650A patent/NO339195B1/no unknown
-
2010
- 2010-04-22 US US12/765,397 patent/US8465726B2/en active Active
- 2010-05-31 IL IL206091A patent/IL206091A/en active IP Right Grant
-
2015
- 2015-02-02 LT LTPA2015005C patent/LTC2213652I2/lt unknown
- 2015-02-04 LU LU92647C patent/LU92647I2/xx unknown
- 2015-02-11 FR FR15C0012C patent/FR15C0012I2/fr active Active
- 2015-02-12 NL NL300719C patent/NL300719I1/nl unknown
- 2015-03-10 BE BE2015C015C patent/BE2015C015I2/nl unknown
- 2015-03-18 HU HUS1500014C patent/HUS1500014I1/hu unknown