AU783960B2 - Tek antagonists - Google Patents
Tek antagonists Download PDFInfo
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- AU783960B2 AU783960B2 AU53282/00A AU5328200A AU783960B2 AU 783960 B2 AU783960 B2 AU 783960B2 AU 53282/00 A AU53282/00 A AU 53282/00A AU 5328200 A AU5328200 A AU 5328200A AU 783960 B2 AU783960 B2 AU 783960B2
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- Prior art keywords
- tek
- polypeptide
- mammal
- soluble
- antibody
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| US13788999P | 1999-06-07 | 1999-06-07 | |
| US60/137889 | 1999-06-07 | ||
| PCT/US2000/015706 WO2000075323A1 (en) | 1999-06-07 | 2000-06-07 | Tek antagonists |
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| AU5328200A AU5328200A (en) | 2000-12-28 |
| AU783960B2 true AU783960B2 (en) | 2006-01-05 |
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| AU53282/00A Ceased AU783960B2 (en) | 1999-06-07 | 2000-06-07 | Tek antagonists |
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| EP (1) | EP1187918B9 (enExample) |
| JP (1) | JP4587626B2 (enExample) |
| AT (1) | ATE324444T1 (enExample) |
| AU (1) | AU783960B2 (enExample) |
| CA (1) | CA2374851A1 (enExample) |
| CY (1) | CY1105078T1 (enExample) |
| DE (1) | DE60027564T3 (enExample) |
| DK (1) | DK1187918T4 (enExample) |
| ES (1) | ES2262518T5 (enExample) |
| IL (2) | IL146482A0 (enExample) |
| NZ (1) | NZ516258A (enExample) |
| PT (1) | PT1187918E (enExample) |
| WO (1) | WO2000075323A1 (enExample) |
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| AU782067B2 (en) | 1999-12-20 | 2005-06-30 | Immunex Corporation | TWEAK receptor |
| EP1427829A4 (en) * | 2001-08-31 | 2005-10-12 | Abmaxis Inc | MULTIVALENT PROTEIN CONJUGATE WITH SEVERAL LIGANDEN BINDING RECORDORDOMAS |
| US7205275B2 (en) | 2001-10-11 | 2007-04-17 | Amgen Inc. | Methods of treatment using specific binding agents of human angiopoietin-2 |
| US7521053B2 (en) | 2001-10-11 | 2009-04-21 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| US7138370B2 (en) | 2001-10-11 | 2006-11-21 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
| US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| CN1315536C (zh) * | 2002-09-13 | 2007-05-16 | 李进 | 肿瘤抗原疫苗及其制备方法和疫苗组合物 |
| JP2007525187A (ja) * | 2003-05-16 | 2007-09-06 | レセプター・バイオロジクス・インコーポレイテッド | イントロン融合タンパク質、ならびにその同定方法および使用方法 |
| RS53476B (sr) | 2003-07-18 | 2014-12-31 | Amgen Fremont Inc. | Sredstva za specifično vezivanje faktora rasta hepatocita |
| US20060286102A1 (en) * | 2004-05-14 | 2006-12-21 | Pei Jin | Cell surface receptor isoforms and methods of identifying and using the same |
| EP1778264A2 (en) * | 2004-06-25 | 2007-05-02 | Licentia, Ltd. | Tie receptor and tie ligand materials and methods for modulating female fertility |
| US7507748B2 (en) * | 2004-07-22 | 2009-03-24 | Amgen Inc. | Substituted aryl-amine derivatives and methods of use |
| WO2006066071A2 (en) * | 2004-12-17 | 2006-06-22 | Mayo Foundation For Medical Education And Research | Prognosis of renal cell carcinoma |
| HRP20110859T1 (hr) | 2004-12-21 | 2011-12-31 | Medimmune Limited | Protutijela usmjerena na angiopoietin-2 i njihova upotreba |
| US20090170769A1 (en) * | 2005-05-13 | 2009-07-02 | Pei Jin | Cell surface receptor isoforms and methods of identifying and using the same |
| AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
| US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| PE20121506A1 (es) | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
| AU2008219166B2 (en) | 2007-02-16 | 2013-05-16 | Amgen Inc. | Nitrogen-containing heterocyclyl ketones and their use as c-Met inhibitors |
| TWI595005B (zh) | 2007-08-21 | 2017-08-11 | 安健股份有限公司 | 人類ｃ－ｆｍｓ抗原結合蛋白質 |
| US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
| US8454960B2 (en) | 2008-01-03 | 2013-06-04 | The Scripps Research Institute | Multispecific antibody targeting and multivalency through modular recognition domains |
| GEP20156390B (en) | 2008-01-03 | 2015-11-10 | Scripps Research Inst | Antibody targeting through a modular recognition domain |
| US8557242B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | ERBB2 antibodies comprising modular recognition domains |
| US8557243B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | EFGR antibodies comprising modular recognition domains |
| EP2247305A4 (en) | 2008-01-28 | 2012-11-14 | Medimmune Ltd | STABILIZED ANGIOPOIETIN-2 ANTIBODIES AND USES THEREOF |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| AU2009262199B2 (en) | 2008-06-27 | 2012-08-09 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
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- 2000-06-07 PT PT00938207T patent/PT1187918E/pt unknown
- 2000-06-07 CA CA002374851A patent/CA2374851A1/en not_active Abandoned
- 2000-06-07 WO PCT/US2000/015706 patent/WO2000075323A1/en not_active Ceased
- 2000-06-07 US US09/590,656 patent/US6413932B1/en not_active Expired - Fee Related
- 2000-06-07 IL IL14648200A patent/IL146482A0/xx unknown
- 2000-06-07 AT AT00938207T patent/ATE324444T1/de not_active IP Right Cessation
- 2000-06-07 DE DE60027564T patent/DE60027564T3/de not_active Expired - Lifetime
- 2000-06-07 EP EP00938207A patent/EP1187918B9/en not_active Expired - Lifetime
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- 2006-07-07 CY CY20061100953T patent/CY1105078T1/el unknown
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| NZ516258A (en) | 2004-02-27 |
| ES2262518T3 (es) | 2006-12-01 |
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| JP2003501090A (ja) | 2003-01-14 |
| IL146482A0 (en) | 2002-07-25 |
| EP1187918B2 (en) | 2009-01-14 |
| AU5328200A (en) | 2000-12-28 |
| US20070025993A1 (en) | 2007-02-01 |
| WO2000075323A1 (en) | 2000-12-14 |
| ES2262518T5 (es) | 2009-05-08 |
| DE60027564T3 (de) | 2009-07-23 |
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