AU768443B2 - Method for stabilising proteins in complex mixtures during their storage in aqueous solvents - Google Patents
Method for stabilising proteins in complex mixtures during their storage in aqueous solvents Download PDFInfo
- Publication number
- AU768443B2 AU768443B2 AU58164/00A AU5816400A AU768443B2 AU 768443 B2 AU768443 B2 AU 768443B2 AU 58164/00 A AU58164/00 A AU 58164/00A AU 5816400 A AU5816400 A AU 5816400A AU 768443 B2 AU768443 B2 AU 768443B2
- Authority
- AU
- Australia
- Prior art keywords
- protein
- insulin
- storage
- cysteine
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19930676 | 1999-07-02 | ||
DE19930676A DE19930676B4 (de) | 1999-07-02 | 1999-07-02 | Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln |
PCT/EP2000/005666 WO2001002435A1 (de) | 1999-07-02 | 2000-06-20 | Verfahren zur stabilisierung von proteinen in komplexen mischungen bei deren lagerung in wässrigen lösungsmitteln |
Publications (2)
Publication Number | Publication Date |
---|---|
AU5816400A AU5816400A (en) | 2001-01-22 |
AU768443B2 true AU768443B2 (en) | 2003-12-11 |
Family
ID=7913515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU58164/00A Expired AU768443B2 (en) | 1999-07-02 | 2000-06-20 | Method for stabilising proteins in complex mixtures during their storage in aqueous solvents |
Country Status (25)
Country | Link |
---|---|
US (3) | US6339061B1 (zh) |
EP (1) | EP1196447B1 (zh) |
JP (1) | JP4555525B2 (zh) |
KR (1) | KR100754235B1 (zh) |
CN (1) | CN1220703C (zh) |
AR (1) | AR024621A1 (zh) |
AT (1) | ATE423137T1 (zh) |
AU (1) | AU768443B2 (zh) |
BR (1) | BRPI0012150B8 (zh) |
CA (1) | CA2377794C (zh) |
CY (1) | CY1109050T1 (zh) |
DE (2) | DE19930676B4 (zh) |
DK (1) | DK1196447T3 (zh) |
ES (1) | ES2321373T3 (zh) |
HK (1) | HK1047115B (zh) |
HU (1) | HU228936B1 (zh) |
IL (2) | IL147250A0 (zh) |
MX (1) | MXPA01012836A (zh) |
NO (1) | NO329429B1 (zh) |
NZ (1) | NZ516372A (zh) |
PL (1) | PL200145B1 (zh) |
PT (1) | PT1196447E (zh) |
SI (1) | SI1196447T1 (zh) |
WO (1) | WO2001002435A1 (zh) |
ZA (1) | ZA200110507B (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10224111A1 (de) * | 2002-05-29 | 2003-12-18 | November Ag Molekulare Medizin | Verfahren zum Assemblieren von Untereinheiten zu Kapsoiden |
US20060201877A1 (en) * | 2005-03-10 | 2006-09-14 | Baldridge John W | Septic system cleaning |
US8116073B2 (en) * | 2010-01-26 | 2012-02-14 | Amtek System Co., Ltd. | Display structure of slip-cover-hinge electronic device |
CN108404194A (zh) * | 2018-04-20 | 2018-08-17 | 朱清 | 一种快速止血纱布的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4371523A (en) * | 1980-12-29 | 1983-02-01 | The Regents Of The University Of California | Reducing the aggregation of insulin in solution |
EP0906918A2 (de) * | 1997-08-18 | 1999-04-07 | Hoechst Marion Roussel Deutschland GmbH | Verfahren zur Gewinnung von Insulinvorläufern mit korrekt verbundenen Cystinbrücken |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI78616C (fi) * | 1982-02-05 | 1989-09-11 | Novo Industri As | Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt. |
DE3583880D1 (de) * | 1984-04-09 | 1991-10-02 | Takeda Chemical Industries Ltd | Stabile interleukin-2-zusammensetzung. |
DK129385A (da) * | 1985-03-22 | 1986-09-23 | Novo Industri As | Peptider og fremstilling deraf |
US4937085A (en) * | 1986-08-15 | 1990-06-26 | Agra-Research, Inc. | Discoloration preventing food preservative and method |
GB8806893D0 (en) * | 1988-03-23 | 1988-04-27 | Unilever Plc | Cosmetic composition |
KR900003362A (ko) * | 1988-08-24 | 1990-03-26 | 전학제 | 유전공학기법을 이용한 인체 인슈린 유사체의 제조방법 |
JPH0341033A (ja) * | 1989-07-07 | 1991-02-21 | Kyowa Hakko Kogyo Co Ltd | 安定なモチリン類含有製剤 |
US5227293A (en) | 1989-08-29 | 1993-07-13 | The General Hospital Corporation | Fusion proteins, their preparation and use |
IL95495A (en) | 1989-08-29 | 1996-10-16 | Hoechst Ag | Fusion proteins their preparation and use |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
IL139335A (en) * | 1994-01-03 | 2005-08-31 | Genentech Inc | Mpl ligand polypeptides, nucleic acids encoding them, vectors and host cells comprising such nucleic acids, processes for producing such polypeptides pharmaceutical compositions containing them and use thereof in the preparation of medicaments for treating thrombocytopenia |
DE4405179A1 (de) * | 1994-02-18 | 1995-08-24 | Hoechst Ag | Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken |
US6165981A (en) * | 1995-03-07 | 2000-12-26 | Dade Behring Inc. | Stabilizing solutions for proteins and peptides |
US5780431A (en) * | 1996-09-20 | 1998-07-14 | Neurobiological Technologies, Inc. | Pharmaceutical formulations of corticotropin releasing factor having improved stability in liquid form |
-
1999
- 1999-07-02 DE DE19930676A patent/DE19930676B4/de not_active Expired - Lifetime
-
2000
- 2000-06-20 IL IL14725000A patent/IL147250A0/xx unknown
- 2000-06-20 CN CNB008091773A patent/CN1220703C/zh not_active Expired - Lifetime
- 2000-06-20 WO PCT/EP2000/005666 patent/WO2001002435A1/de active Application Filing
- 2000-06-20 KR KR1020027000032A patent/KR100754235B1/ko active IP Right Grant
- 2000-06-20 DK DK00943838T patent/DK1196447T3/da active
- 2000-06-20 DE DE50015562T patent/DE50015562D1/de not_active Expired - Lifetime
- 2000-06-20 AU AU58164/00A patent/AU768443B2/en not_active Expired
- 2000-06-20 BR BRPI0012150A patent/BRPI0012150B8/pt not_active IP Right Cessation
- 2000-06-20 PT PT00943838T patent/PT1196447E/pt unknown
- 2000-06-20 SI SI200031027T patent/SI1196447T1/sl unknown
- 2000-06-20 JP JP2001508222A patent/JP4555525B2/ja not_active Expired - Lifetime
- 2000-06-20 HU HU0202264A patent/HU228936B1/hu unknown
- 2000-06-20 ES ES00943838T patent/ES2321373T3/es not_active Expired - Lifetime
- 2000-06-20 MX MXPA01012836A patent/MXPA01012836A/es active IP Right Grant
- 2000-06-20 NZ NZ516372A patent/NZ516372A/xx not_active IP Right Cessation
- 2000-06-20 CA CA2377794A patent/CA2377794C/en not_active Expired - Lifetime
- 2000-06-20 AT AT00943838T patent/ATE423137T1/de active
- 2000-06-20 PL PL353160A patent/PL200145B1/pl unknown
- 2000-06-20 EP EP00943838A patent/EP1196447B1/de not_active Expired - Lifetime
- 2000-06-29 AR ARP000103312A patent/AR024621A1/es active IP Right Grant
- 2000-06-30 US US09/608,297 patent/US6339061B1/en not_active Expired - Lifetime
-
2001
- 2001-11-26 US US09/991,964 patent/US6734164B2/en not_active Expired - Lifetime
- 2001-12-12 NO NO20016071A patent/NO329429B1/no not_active IP Right Cessation
- 2001-12-21 ZA ZA200110507A patent/ZA200110507B/xx unknown
- 2001-12-23 IL IL147250A patent/IL147250A/en active IP Right Grant
-
2002
- 2002-11-29 HK HK02108639.8A patent/HK1047115B/zh not_active IP Right Cessation
-
2004
- 2004-03-10 US US10/796,160 patent/US7514403B2/en not_active Expired - Fee Related
-
2009
- 2009-05-11 CY CY20091100502T patent/CY1109050T1/el unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4371523A (en) * | 1980-12-29 | 1983-02-01 | The Regents Of The University Of California | Reducing the aggregation of insulin in solution |
EP0906918A2 (de) * | 1997-08-18 | 1999-04-07 | Hoechst Marion Roussel Deutschland GmbH | Verfahren zur Gewinnung von Insulinvorläufern mit korrekt verbundenen Cystinbrücken |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) | ||
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |