SI1196447T1 - Postopek za stabiliziranje proteinov v kompleksnih zmeseh pri njihovem shranjevanju v vodnih topilih - Google Patents

Postopek za stabiliziranje proteinov v kompleksnih zmeseh pri njihovem shranjevanju v vodnih topilih

Info

Publication number
SI1196447T1
SI1196447T1 SI200031027T SI200031027T SI1196447T1 SI 1196447 T1 SI1196447 T1 SI 1196447T1 SI 200031027 T SI200031027 T SI 200031027T SI 200031027 T SI200031027 T SI 200031027T SI 1196447 T1 SI1196447 T1 SI 1196447T1
Authority
SI
Slovenia
Prior art keywords
storage
aqueous solvents
complex mixtures
mixtures during
stabilising proteins
Prior art date
Application number
SI200031027T
Other languages
English (en)
Inventor
Franz-Josef Rubroeder
Reinhold Keller
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of SI1196447T1 publication Critical patent/SI1196447T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SI200031027T 1999-07-02 2000-06-20 Postopek za stabiliziranje proteinov v kompleksnih zmeseh pri njihovem shranjevanju v vodnih topilih SI1196447T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19930676A DE19930676B4 (de) 1999-07-02 1999-07-02 Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln
EP00943838A EP1196447B1 (de) 1999-07-02 2000-06-20 Verfahren zur stabilisierung von proteinen in komplexen mischungen bei deren lagerung in wässrigen lösungsmitteln
PCT/EP2000/005666 WO2001002435A1 (de) 1999-07-02 2000-06-20 Verfahren zur stabilisierung von proteinen in komplexen mischungen bei deren lagerung in wässrigen lösungsmitteln

Publications (1)

Publication Number Publication Date
SI1196447T1 true SI1196447T1 (sl) 2009-08-31

Family

ID=7913515

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200031027T SI1196447T1 (sl) 1999-07-02 2000-06-20 Postopek za stabiliziranje proteinov v kompleksnih zmeseh pri njihovem shranjevanju v vodnih topilih

Country Status (25)

Country Link
US (3) US6339061B1 (sl)
EP (1) EP1196447B1 (sl)
JP (1) JP4555525B2 (sl)
KR (1) KR100754235B1 (sl)
CN (1) CN1220703C (sl)
AR (1) AR024621A1 (sl)
AT (1) ATE423137T1 (sl)
AU (1) AU768443B2 (sl)
BR (1) BRPI0012150B8 (sl)
CA (1) CA2377794C (sl)
CY (1) CY1109050T1 (sl)
DE (2) DE19930676B4 (sl)
DK (1) DK1196447T3 (sl)
ES (1) ES2321373T3 (sl)
HK (1) HK1047115B (sl)
HU (1) HU228936B1 (sl)
IL (2) IL147250A0 (sl)
MX (1) MXPA01012836A (sl)
NO (1) NO329429B1 (sl)
NZ (1) NZ516372A (sl)
PL (1) PL200145B1 (sl)
PT (1) PT1196447E (sl)
SI (1) SI1196447T1 (sl)
WO (1) WO2001002435A1 (sl)
ZA (1) ZA200110507B (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10224111A1 (de) * 2002-05-29 2003-12-18 November Ag Molekulare Medizin Verfahren zum Assemblieren von Untereinheiten zu Kapsoiden
US20060201877A1 (en) * 2005-03-10 2006-09-14 Baldridge John W Septic system cleaning
US8116073B2 (en) * 2010-01-26 2012-02-14 Amtek System Co., Ltd. Display structure of slip-cover-hinge electronic device
CN108404194A (zh) * 2018-04-20 2018-08-17 朱清 一种快速止血纱布的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371523A (en) * 1980-12-29 1983-02-01 The Regents Of The University Of California Reducing the aggregation of insulin in solution
FI78616C (fi) * 1982-02-05 1989-09-11 Novo Industri As Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt.
DE3583880D1 (de) * 1984-04-09 1991-10-02 Takeda Chemical Industries Ltd Stabile interleukin-2-zusammensetzung.
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
US4937085A (en) * 1986-08-15 1990-06-26 Agra-Research, Inc. Discoloration preventing food preservative and method
GB8806893D0 (en) * 1988-03-23 1988-04-27 Unilever Plc Cosmetic composition
KR900003362A (ko) * 1988-08-24 1990-03-26 전학제 유전공학기법을 이용한 인체 인슈린 유사체의 제조방법
JPH0341033A (ja) * 1989-07-07 1991-02-21 Kyowa Hakko Kogyo Co Ltd 安定なモチリン類含有製剤
US5227293A (en) 1989-08-29 1993-07-13 The General Hospital Corporation Fusion proteins, their preparation and use
IL95495A (en) 1989-08-29 1996-10-16 Hoechst Ag Fusion proteins their preparation and use
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
IL139335A (en) * 1994-01-03 2005-08-31 Genentech Inc Mpl ligand polypeptides, nucleic acids encoding them, vectors and host cells comprising such nucleic acids, processes for producing such polypeptides pharmaceutical compositions containing them and use thereof in the preparation of medicaments for treating thrombocytopenia
DE4405179A1 (de) * 1994-02-18 1995-08-24 Hoechst Ag Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
US6165981A (en) * 1995-03-07 2000-12-26 Dade Behring Inc. Stabilizing solutions for proteins and peptides
US5780431A (en) * 1996-09-20 1998-07-14 Neurobiological Technologies, Inc. Pharmaceutical formulations of corticotropin releasing factor having improved stability in liquid form
DE19735711C2 (de) * 1997-08-18 2001-04-26 Aventis Pharma Gmbh Verfahren zur Herstellung eines Vorläufers von Insulin oder Insulinderivaten mit korrekt verbundenen Cystinbrücken

Also Published As

Publication number Publication date
EP1196447A1 (de) 2002-04-17
CA2377794C (en) 2011-12-06
JP2003504313A (ja) 2003-02-04
JP4555525B2 (ja) 2010-10-06
IL147250A (en) 2010-02-17
PT1196447E (pt) 2009-04-20
BR0012150A (pt) 2002-05-21
MXPA01012836A (es) 2002-07-30
DK1196447T3 (da) 2009-06-15
ATE423137T1 (de) 2009-03-15
IL147250A0 (en) 2002-08-14
PL353160A1 (en) 2003-10-20
US7514403B2 (en) 2009-04-07
CN1357008A (zh) 2002-07-03
PL200145B1 (pl) 2008-12-31
NO20016071L (no) 2001-12-12
KR20020026515A (ko) 2002-04-10
AU768443B2 (en) 2003-12-11
US6339061B1 (en) 2002-01-15
HUP0202264A3 (en) 2005-01-28
KR100754235B1 (ko) 2007-09-03
AU5816400A (en) 2001-01-22
NZ516372A (en) 2004-03-26
US6734164B2 (en) 2004-05-11
DE50015562D1 (de) 2009-04-02
DE19930676A1 (de) 2001-01-18
US20040230038A1 (en) 2004-11-18
HK1047115B (zh) 2006-02-24
NO20016071D0 (no) 2001-12-12
BRPI0012150B1 (pt) 2016-06-14
CN1220703C (zh) 2005-09-28
HU228936B1 (en) 2013-06-28
ZA200110507B (en) 2002-07-24
CA2377794A1 (en) 2001-01-11
CY1109050T1 (el) 2014-07-02
ES2321373T3 (es) 2009-06-05
AR024621A1 (es) 2002-10-16
EP1196447B1 (de) 2009-02-18
NO329429B1 (no) 2010-10-18
HUP0202264A2 (en) 2002-10-28
US20020058623A1 (en) 2002-05-16
BRPI0012150B8 (pt) 2021-05-25
HK1047115A1 (en) 2003-02-07
DE19930676B4 (de) 2006-01-19
WO2001002435A1 (de) 2001-01-11

Similar Documents

Publication Publication Date Title
HUP0200297A3 (en) Method for acylating peptides and the glutaminic acid derivatives as acylating agents
AU7924700A (en) Dry-cleaning solvent and method for using the same
HK1052699A1 (zh) 3-羥基吡啶甲酸衍生物的製備方法
IL155820A0 (en) System, method and program for storing objects
GB0015426D0 (en) Method for generating soluble highly multimeric proteins
ID30213A (id) Proses untuk karbonilasi diena gabungan
AU3353499A (en) Process for hydrocarbonylations in supercritical carbon dioxide
GB2329875B (en) Inflatable floor,in particular for an inflatable boat
AU2001280831A1 (en) Method and apparatus for unloading gradients
AU2001229556A1 (en) Method and apparatus for low voltage sensing in flash memories
HK1047115A1 (en) Method for stabilising proteins in complex mixtures during their storage in aqueous solvents
AU6124201A (en) A method and device for improving protein stability and solubility
MXPA02012047A (es) Metodo y aparato para modificar el almacenamiento persistente.
HUP0102444A3 (en) Protein c derivatives
HUP0105427A3 (en) Method for drying protein crystals
EP1305331A4 (en) MOTOR PROTEINS AND METHOD OF USE THEREOF
HUP0200058A3 (en) Method for crystallising n-(4-trifluoromethylphenyl)-5-methyl-isoxazole-4-carboxamide
GB9907366D0 (en) Method for expressing proteins
EP1081231A4 (en) METHOD FOR OBTAINING SOLUBLE PROTEIN.
AU2227301A (en) Method and device for drying washed objects
GB9905164D0 (en) Method for protein folding
GB0207050D0 (en) Graphics substream bypass method and apparatus
GB9914524D0 (en) Method for generating soluble highly multimeric proteins
GB0004184D0 (en) Method for protein folding
TW342686U (en) Expansible handling-frame for multi-layers placing addition (I)