AU725760B2 - Process for making flurbiprofen lozenges - Google Patents

Process for making flurbiprofen lozenges Download PDF

Info

Publication number
AU725760B2
AU725760B2 AU79165/98A AU7916598A AU725760B2 AU 725760 B2 AU725760 B2 AU 725760B2 AU 79165/98 A AU79165/98 A AU 79165/98A AU 7916598 A AU7916598 A AU 7916598A AU 725760 B2 AU725760 B2 AU 725760B2
Authority
AU
Australia
Prior art keywords
lozenge
flurbiprofen
forming composition
mixture
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU79165/98A
Other languages
English (en)
Other versions
AU7916598A (en
Inventor
Andrew Day
Huw Lyn Jones
Carl Simon Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of AU7916598A publication Critical patent/AU7916598A/en
Application granted granted Critical
Publication of AU725760B2 publication Critical patent/AU725760B2/en
Assigned to RECKITT BENCKISER HEALTHCARE (UK) LIMITED reassignment RECKITT BENCKISER HEALTHCARE (UK) LIMITED Alteration of Name(s) in Register under S187 Assignors: BOOTS COMPANY PLC, THE
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU79165/98A 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges Ceased AU725760B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9710521.7A GB9710521D0 (en) 1997-05-22 1997-05-22 Process
GB9710521 1997-05-22
PCT/EP1998/003167 WO1998052539A1 (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges

Publications (2)

Publication Number Publication Date
AU7916598A AU7916598A (en) 1998-12-11
AU725760B2 true AU725760B2 (en) 2000-10-19

Family

ID=10812840

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79165/98A Ceased AU725760B2 (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges

Country Status (31)

Country Link
US (1) US6194003B1 (h)
EP (1) EP0983059B1 (h)
JP (1) JP2001527567A (h)
KR (1) KR20010012739A (h)
CN (1) CN1154480C (h)
AR (1) AR015812A1 (h)
AT (1) ATE245021T1 (h)
AU (1) AU725760B2 (h)
BG (1) BG103881A (h)
BR (1) BR9809651A (h)
CA (1) CA2290830C (h)
CZ (1) CZ290816B6 (h)
DE (1) DE69816440T2 (h)
DK (1) DK0983059T3 (h)
ES (1) ES2202871T3 (h)
GB (1) GB9710521D0 (h)
HU (1) HU224954B1 (h)
ID (1) ID22949A (h)
IL (1) IL132999A0 (h)
IN (1) IN187837B (h)
MY (1) MY118410A (h)
NO (1) NO995681D0 (h)
NZ (1) NZ500664A (h)
PL (1) PL190947B1 (h)
PT (1) PT983059E (h)
RU (1) RU2203046C2 (h)
SK (1) SK283701B6 (h)
TR (1) TR199902725T2 (h)
UA (1) UA53714C2 (h)
WO (1) WO1998052539A1 (h)
ZA (1) ZA984260B (h)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124124B2 (en) 1999-12-09 2012-02-28 Reckitt Benckiser Healthcare (Uk) Limited Compressed tablet formulation comprising non-steroidal anti-inflammatory drugs and methods
WO2001078721A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research Aβ42 LOWERING AGENTS
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
US20050042284A1 (en) * 2003-07-11 2005-02-24 Myriad Genetics, Incorporated Pharmaceutical methods, dosing regimes and dosage forms for the treatment of Alzheimer's disease
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
EP1745180A1 (en) * 2004-04-29 2007-01-24 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CA2644400C (en) 2005-02-03 2014-04-08 Nycomed Pharma As Fast wet-massing method for the preparation of calcium-containing compositions
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
EP1909777A2 (en) * 2005-07-22 2008-04-16 Myriad Genetics, Inc. High drug load formulations and dosage forms
CN103622926A (zh) * 2005-11-02 2014-03-12 帝国制药美国公司 感官上可接受的布洛芬口服给药制剂、制备和使用它的方法
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
KR20100020449A (ko) * 2007-07-23 2010-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 기호적으로 허용될 수 있는 인돌 세로토닌 수용체 작용제 경구 투여 제제 및 이를 사용하는 방법
WO2010020772A2 (en) * 2008-08-22 2010-02-25 Reckitt Benckiser Healthcare (Uk) Limited Improvements in or relating to compositions
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
IT1406107B1 (it) * 2010-12-13 2014-02-14 Alfa Wassermann Spa Composizioni solide comprendenti antiinfiammatori non steroidei, processi per la loro preparazione e loro uso.
CA2860373C (en) 2011-04-29 2017-08-15 Moberg Pharma Ab Pharmaceutical compositions comprising a local anaesthetic such as bupivacaine for local administration to the mouth or throat
EP2609911A1 (en) * 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. A novel process for preparing orally disintegrating flurbiprofen formulations
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
US20180228832A1 (en) * 2015-08-18 2018-08-16 Pharma Seeds Create, Llc Stomatological composition containing nsaid or heparin compound
WO2020013781A2 (en) * 2018-03-27 2020-01-16 Pisak Mehmet Nevzat Synergistic effect of flurbiprofen and a gastro protective agent for the treatment of pain and inflammation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753296A2 (en) * 1995-06-13 1997-01-15 American Home Products Corporation Oral formulations of S(+)-ibuprofen
AU2611997A (en) * 1995-11-22 1997-06-11 Reckitt Benckiser Healthcare (Uk) Limited Medical Treatment

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4666716A (en) * 1984-09-04 1987-05-19 Richardson-Vicks Inc. Antidiarrheal compositions and use thereof
RU2026670C1 (ru) * 1988-10-05 1995-01-20 Дзе Апджон Компани Способ получения тонкодисперсного твердого фармацевтического вещества
IT1243342B (it) 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
IT1244698B (it) * 1991-02-01 1994-08-08 Gentili Ist Spa Acidi aril-o arilalchil-acil ammino-alchil-idrossidifosfonici, procedimento per la loro preparazione e loro uso in terapia osteo-articolare e dei tessuti connettori in generale
US5302394A (en) * 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753296A2 (en) * 1995-06-13 1997-01-15 American Home Products Corporation Oral formulations of S(+)-ibuprofen
AU2611997A (en) * 1995-11-22 1997-06-11 Reckitt Benckiser Healthcare (Uk) Limited Medical Treatment

Also Published As

Publication number Publication date
CN1255848A (zh) 2000-06-07
GB9710521D0 (en) 1997-07-16
RU2203046C2 (ru) 2003-04-27
EP0983059B1 (en) 2003-07-16
BR9809651A (pt) 2000-07-11
IN187837B (h) 2002-06-29
NO995681L (no) 1999-11-19
PL190947B1 (pl) 2006-02-28
SK283701B6 (sk) 2003-12-02
US6194003B1 (en) 2001-02-27
NO995681D0 (no) 1999-11-19
CZ412099A3 (cs) 2000-02-16
KR20010012739A (ko) 2001-02-26
BG103881A (bg) 2000-05-31
NZ500664A (en) 2001-01-26
CA2290830C (en) 2006-07-11
ATE245021T1 (de) 2003-08-15
AR015812A1 (es) 2001-05-30
EP0983059A1 (en) 2000-03-08
WO1998052539A1 (en) 1998-11-26
PT983059E (pt) 2003-11-28
PL336624A1 (en) 2000-07-03
HUP0002121A2 (hu) 2000-12-28
JP2001527567A (ja) 2001-12-25
ZA984260B (en) 1999-02-20
ID22949A (id) 1999-12-16
DK0983059T3 (da) 2003-11-03
TR199902725T2 (xx) 2000-02-21
DE69816440D1 (de) 2003-08-21
DE69816440T2 (de) 2004-05-13
SK158899A3 (en) 2000-05-16
HU224954B1 (en) 2006-04-28
CN1154480C (zh) 2004-06-23
AU7916598A (en) 1998-12-11
IL132999A0 (en) 2001-03-19
HUP0002121A3 (en) 2001-04-28
CA2290830A1 (en) 1998-11-26
UA53714C2 (uk) 2003-02-17
ES2202871T3 (es) 2004-04-01
MY118410A (en) 2004-10-30
CZ290816B6 (cs) 2002-10-16

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FGA Letters patent sealed or granted (standard patent)