AU626516B2 - Extracts of nerium species, methods of preparation, and use therefor - Google Patents

Extracts of nerium species, methods of preparation, and use therefor Download PDF

Info

Publication number
AU626516B2
AU626516B2 AU72785/87A AU7278587A AU626516B2 AU 626516 B2 AU626516 B2 AU 626516B2 AU 72785/87 A AU72785/87 A AU 72785/87A AU 7278587 A AU7278587 A AU 7278587A AU 626516 B2 AU626516 B2 AU 626516B2
Authority
AU
Australia
Prior art keywords
extract
patient
nerium
noi
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU72785/87A
Other languages
English (en)
Other versions
AU7278587A (en
Inventor
Huseyin Ziya Ozel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU7278587A publication Critical patent/AU7278587A/en
Application granted granted Critical
Publication of AU626516B2 publication Critical patent/AU626516B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/415—Assays involving biological materials from specific organisms or of a specific nature from plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU72785/87A 1986-05-13 1987-05-13 Extracts of nerium species, methods of preparation, and use therefor Expired AU626516B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US86272086A 1986-05-13 1986-05-13
US862720 1986-05-13
US4843587A 1987-05-11 1987-05-11
US048435 1987-05-11

Publications (2)

Publication Number Publication Date
AU7278587A AU7278587A (en) 1987-11-19
AU626516B2 true AU626516B2 (en) 1992-08-06

Family

ID=26726121

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72785/87A Expired AU626516B2 (en) 1986-05-13 1987-05-13 Extracts of nerium species, methods of preparation, and use therefor

Country Status (14)

Country Link
US (1) US5135745A (OSRAM)
JP (1) JPS6322025A (OSRAM)
KR (1) KR880013565A (OSRAM)
CN (1) CN87104312A (OSRAM)
AU (1) AU626516B2 (OSRAM)
CA (1) CA1299100C (OSRAM)
DK (1) DK239687A (OSRAM)
FI (1) FI872106A7 (OSRAM)
IL (1) IL82516A0 (OSRAM)
IN (1) IN165073B (OSRAM)
MC (1) MC1811A1 (OSRAM)
NO (1) NO871978L (OSRAM)
NZ (1) NZ220295A (OSRAM)
PT (1) PT84857B (OSRAM)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003227319B2 (en) * 1998-09-24 2007-07-26 Ozelle Pharmaceuticals, Inc. Extract of nerium species, pharmaceutical composition thereof and methods for preparation thereof
CA2354037A1 (en) * 1998-09-24 2000-03-30 Ozelle Pharmaceuticals, Inc. Extract of nerium species, pharmaceutical composition thereof and methods for preparation thereof
KR100478146B1 (ko) * 2002-08-30 2005-03-22 재단법인 포항산업과학연구원 협죽도과 식물의 잎 추출물을 함유하는 고려잔디갈색퍼짐병 방제용 조성물 및 이를 이용하여 갈색퍼짐병을방제하는 방법
US20050112059A1 (en) * 2003-10-06 2005-05-26 Phoenix Biotechnology, Inc. Enhancement of radiotherapy by an exogenous cardiac glycoside
US20050250709A1 (en) * 2003-12-19 2005-11-10 Bionaut Pharmaceuticals Anti-neoplastic agents, combination therapies and related methods
JP2005289963A (ja) * 2004-03-12 2005-10-20 Hokubu Norin Koto Gakko Koenkai 抗腫瘍剤
US20070105790A1 (en) * 2004-09-02 2007-05-10 Bionaut Pharmaceuticals, Inc. Pancreatic cancer treatment using Na+/K+ ATPase inhibitors
US20080027010A1 (en) * 2004-09-02 2008-01-31 Bionaut Pharmaceuticals, Inc. Treatment of refractory cancers using Na+/K+-ATPase inhibitors
EP1789090A2 (en) * 2004-09-02 2007-05-30 Bionaut Pharmaceuticals, Inc. Combinatorial chemotherapy treatment using na+/k+-atpase inhibitors
US20060135468A1 (en) * 2004-09-02 2006-06-22 Bionaut Pharmaceuticals, Inc. Treatment of refractory cancers using NA+/K+ ATPase inhibitors
US20060135442A1 (en) * 2004-09-02 2006-06-22 Bionaut Pharmaceuticals, Inc. Pancreatic cancer treatment using Na+/K+ ATPase inhibitors
US20060135443A1 (en) * 2004-10-18 2006-06-22 Bionaut Pharmaceuticals, Inc. Use of Na*/K*-ATPase inhibitors and antagonists thereof
US20060188536A1 (en) * 2005-02-15 2006-08-24 Phoenix Biotechnology Inc. Particles from processing of oleander leaves
JP2007008879A (ja) * 2005-06-30 2007-01-18 Yanbaru Green Health:Kk 抗腫瘍剤及びこれを含有する食品
US7402325B2 (en) * 2005-07-28 2008-07-22 Phoenix Biotechnology, Inc. Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
EP1803461A1 (en) * 2005-12-27 2007-07-04 Heinz-Herbert Fiebig Therapeutic use of an extract from the leaves of Nerium oleander
WO2008078362A1 (ja) * 2006-12-22 2008-07-03 The Institute Of Biological Resources 抗腫瘍剤及びこれを含有する食品
US8486465B1 (en) * 2007-07-09 2013-07-16 Douglas CRAWFORD Therapeutic nerium oleander extract compositions and methods of using
CN101613414B (zh) * 2008-06-26 2011-09-07 中国科学院上海药物研究所 两种夹竹桃寡糖及其制备方法和用途
RU2530654C2 (ru) 2008-10-14 2014-10-10 Нериум Биотекнолоджи, Инк. Способ экстракции сердечных гликозидов и композиции на их оcнове
CN101416988B (zh) * 2008-12-07 2011-12-21 中国热带农业科学院热带生物技术研究所 采食长春花叶的夹竹桃天蛾幼虫粪便提取物在制备抗肿瘤药物中的用途
TR200900312A2 (tr) * 2009-01-15 2010-08-23 Levent Baş Ahmet Nerium oleander'in tip II diyabet, obezite, yüksek kolesterol ve trigliserid düzeyi ile seyreden hastalıklar ve kardiovasküler hastalıklarda kullanımı@
AU2012325819B2 (en) 2011-10-20 2017-08-03 Nerium Biotechnology, Inc. Therapeutic combination for the treatment of cancer
ES2874187T3 (es) 2016-09-14 2021-11-04 Phoenix Biotechnology Inc Método y composiciones para el tratamiento de una infección viral
US10596186B2 (en) 2016-09-14 2020-03-24 Phoenix Biotechnology, Inc. Method and compositions for treating viral infections
US10702567B2 (en) 2016-09-14 2020-07-07 Phoenix Biotechnology, Inc. Method and compositions for treating viral infection
US10729735B1 (en) 2016-09-14 2020-08-04 Phoenix Biotechnology, Inc. Method and compostitions for treating coronavirus infection
CA3075729A1 (en) 2017-09-14 2019-03-21 Phoenix Biotechnology, Inc. Use of oleandrin to treatn viral infection
ES2965161T3 (es) * 2020-03-31 2024-04-11 Phoenix Biotechnology Inc Método y composiciones para el tratamiento de infección por coronavirus
US11806359B2 (en) 2020-03-31 2023-11-07 Phoenix Biotechnology, Inc. Method and compositions for treating Coronavirus infection
SG11202105728YA (en) 2020-03-31 2021-11-29 Phoenix Biotechnology Inc Method and compositions for treating coronavirus infection
CA3091376C (en) * 2020-03-31 2023-09-19 Phoenix Biotechnology, Inc. Method and compositions for treating coronavirus infection
EP4295854A3 (en) 2020-03-31 2024-04-03 Phoenix Biotechnology, Inc. Method and compositions for treating coronavirus infection
US12097234B2 (en) 2020-05-24 2024-09-24 Phoenix Biotechnology, Inc. Extract containing oleandrin and method of production thereof

Also Published As

Publication number Publication date
FI872106L (fi) 1987-11-14
IL82516A0 (en) 1987-11-30
KR880013565A (ko) 1988-12-21
JPH0529332B2 (OSRAM) 1993-04-30
CA1299100C (en) 1992-04-21
NO871978D0 (no) 1987-05-13
AU7278587A (en) 1987-11-19
FI872106A0 (fi) 1987-05-12
DK239687D0 (da) 1987-05-12
IN165073B (OSRAM) 1989-08-12
PT84857A (en) 1987-06-01
FI872106A7 (fi) 1987-11-14
DK239687A (da) 1987-11-14
CN87104312A (zh) 1988-01-13
PT84857B (pt) 1990-02-08
MC1811A1 (fr) 1988-03-18
NO871978L (no) 1987-11-16
US5135745A (en) 1992-08-04
JPS6322025A (ja) 1988-01-29
NZ220295A (en) 1990-04-26

Similar Documents

Publication Publication Date Title
US5135745A (en) Extracts of nerium species, methods of preparation, and use therefore
Fairley et al. Clinical and biochemical syndrome in lymphadenoma
Shaffer Liquefying nodular panniculitis: report of a case
EP0246069B1 (en) Extracts of nerium species, methods of preparation, and use therefore
Mayon-White et al. A case of limb compression ending fatally in uraemia
CN108186794B (zh) 一种治疗肺癌的中药组合物及其制备方法和应用
CN105687422A (zh) 一种树莓组合物及其用途
CN104784670A (zh) 一种治疗心肌炎的药物组合物及其制备方法
CN103919810A (zh) 一种蕲蛇水溶性总蛋白冻干粉的制备方法
Duncan et al. Argentaffin carcinoma of ileum with raised serum 5-hydroxytryptamine
Butlin On Malignant Disease, Sarcoma and Carcinoma, of the Larynx
CN111298061B (zh) 一种清热解毒、祛瘀散结的中药组合物及其制备方法
Reid Dinitrophenol and diabetes mellitus
Henneford et al. The time of appearance of metastases after surgical removal of the primary tumor
CN120837539B (zh) 一种白术制剂及其用途
KR20040079724A (ko) 만성 간염 치료효과를 갖는 복합 한약제제
CN103751533B (zh) 一种用于精索静脉曲张术后的中药外用制剂及其制备方法
AU2017200088B2 (en) Herbal formulations of carnivorous plants and methods for treating inflammation
Mohs Lack of estrin concentration in adenofibroma of the mammary gland in rats
Kazansky Cancer and Its Prophylactics: Modern Theory of Malignant Tumours
SU1651781A3 (ru) Способ получени экстракта, обладающего противоопухолевой активностью
Williams Pulmonary Consumption: Its Etiology, Pathology, and Treatment...
CN105663434A (zh) 一种治疗变应性皮肤血管炎的中药及制备方法
Sarhat STUDY OF THE EFFECT OF CASTOR SEEDS (RICINUS COMMUNIS LINN.) ON OVARY FUNCTIONS AND CHARACTERS OF FEMALE RABBITS
Prashanth Comparative study on janu basti and janu pichu with murivenna in janu sandhi gata vata