|
WO2000012758A1
(en)
*
|
1998-09-02 |
2000-03-09 |
Diadexus Llc |
A novel method of diagnosing, monitoring, staging, imaging and treating various cancers
|
|
US6902892B1
(en)
|
1998-10-19 |
2005-06-07 |
Diadexus, Inc. |
Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
|
|
JP3764286B2
(ja)
*
|
1998-11-12 |
2006-04-05 |
独立行政法人科学技術振興機構 |
タンパク質AMSHとそのcDNA
|
|
US6699664B1
(en)
|
1998-12-17 |
2004-03-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
CZ303339B6
(cs)
*
|
1998-12-17 |
2012-08-08 |
Corixa Corporation |
Izolovaná protilátka nebo její fragment vázající antigen, jejich použití a farmaceutický prostredek pro lécení ovariálního karcinomu
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6962980B2
(en)
*
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US7888477B2
(en)
|
1998-12-17 |
2011-02-15 |
Corixa Corporation |
Ovarian cancer-associated antibodies and kits
|
|
US20020119158A1
(en)
*
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6670463B1
(en)
|
1998-12-17 |
2003-12-30 |
Corixa Corporation |
Compositions and methods for therapy of ovarian cancer
|
|
US20030009013A1
(en)
*
|
1998-12-30 |
2003-01-09 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
EP1623991A3
(en)
*
|
1999-09-01 |
2006-06-07 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
EP1248800A2
(en)
|
1999-11-30 |
2002-10-16 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
|
US20020146727A1
(en)
*
|
1999-11-30 |
2002-10-10 |
Dillon Davin C. |
Compositions and methods for the therapy and diagnosis of breast cancer
|
|
AU3483001A
(en)
*
|
2000-02-04 |
2001-08-14 |
Corixa Corp |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
AU2001275437A1
(en)
*
|
2000-06-09 |
2001-12-17 |
Idec Pharmaceuticals Corporation |
Gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
|
EP1301524A1
(en)
*
|
2000-06-30 |
2003-04-16 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
|
WO2002002624A2
(en)
*
|
2000-06-30 |
2002-01-10 |
Amgen, Inc. |
B7-like molecules and uses thereof
|
|
US20110177082A1
(en)
*
|
2000-07-17 |
2011-07-21 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
KR100935092B1
(ko)
*
|
2000-07-17 |
2010-01-08 |
코릭사 코포레이션 |
난소암의 치료 및 진단용 조성물 및 방법
|
|
US6891030B2
(en)
*
|
2000-07-27 |
2005-05-10 |
Mayo Foundation For Medical Education And Research |
T-cell immunoregulatory molecule
|
|
ATE532860T1
(de)
|
2000-09-20 |
2011-11-15 |
Amgen Inc |
B7-ähnliche moleküle und deren anwendungen
|
|
US7524509B2
(en)
|
2001-03-09 |
2009-04-28 |
Id Biomedical Corporation Of Quebec |
Proteosome-liposaccharide vaccine adjuvant
|
|
US7309760B2
(en)
*
|
2001-04-17 |
2007-12-18 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions
|
|
CA2443617C
(en)
*
|
2001-04-17 |
2013-12-10 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
|
|
WO2002097046A2
(en)
|
2001-05-25 |
2002-12-05 |
Amgen, Inc. |
B7 related protein-2 molecules and uses thereof
|
|
US9222938B2
(en)
*
|
2001-12-04 |
2015-12-29 |
Michael Tainsky |
Neoepitope detection of disease using protein arrays
|
|
US20030190621A1
(en)
*
|
2002-03-20 |
2003-10-09 |
Ken-Shwo Dai |
Human CrkRS-related gene variant associated with lung cancers
|
|
WO2003097878A1
(en)
*
|
2002-05-21 |
2003-11-27 |
Sysmex Corporation |
Nucleic acid amplification primers for detecting cytokeratins and examination method with the use of the primers
|
|
US9200036B2
(en)
|
2002-07-12 |
2015-12-01 |
The Johns Hopkins University |
Mesothelin vaccines and model systems
|
|
US20090110702A1
(en)
|
2002-07-12 |
2009-04-30 |
The Johns Hopkins University |
Mesothelin Vaccines and Model Systems and Control of Tumors
|
|
CA2492160A1
(en)
|
2002-07-12 |
2004-01-22 |
The Johns Hopkins University |
Mesothelin vaccines and model systems
|
|
WO2004035537A2
(en)
|
2002-10-16 |
2004-04-29 |
Euro-Celtique S.A. |
Antibodies that bind cell-associated ca 125/o772p and methods of use thereof
|
|
UA89348C2
(ru)
*
|
2002-10-16 |
2010-01-25 |
Евро-Селтик С.А. |
Изолированное моноклональное антитело, которое связывает клеточно-ассоциированный полипептид са 125/о772р
|
|
WO2004045553A2
(en)
*
|
2002-11-15 |
2004-06-03 |
The Board Of Trustees Of The University Of Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
|
EP1581641A4
(en)
*
|
2002-12-06 |
2006-11-15 |
Diadexus Inc |
COMPOSITIONS, SPREADING VARIATIONS AND METHODS RELATED TO OVARAL SPECIFIC GENES AND PROTEINS
|
|
WO2004092407A1
(en)
*
|
2003-04-17 |
2004-10-28 |
Genesis Group Inc. |
Pygopus in diagnosis and treatment of cancer
|
|
WO2004101756A2
(en)
*
|
2003-05-09 |
2004-11-25 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
|
US20050163772A1
(en)
*
|
2003-06-16 |
2005-07-28 |
University Of Washington |
B7S1: an immune modulator
|
|
EP2311468B1
(en)
|
2003-08-08 |
2014-01-15 |
Perseus Proteomics Inc. |
Gene overexpressed in cancer
|
|
EP2478912B1
(en)
|
2003-11-06 |
2016-08-31 |
Seattle Genetics, Inc. |
Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy
|
|
US20050186577A1
(en)
|
2004-02-20 |
2005-08-25 |
Yixin Wang |
Breast cancer prognostics
|
|
US7192709B2
(en)
*
|
2004-03-15 |
2007-03-20 |
Digigenomics Co., Ltd. |
Methods for identification, assessment, prevention, and therapy of cancer
|
|
NZ579482A
(en)
|
2004-06-01 |
2011-02-25 |
Genentech Inc |
Antibody drug conjugates and methods
|
|
DK1791565T3
(en)
|
2004-09-23 |
2016-08-01 |
Genentech Inc |
Cysteingensplejsede antibodies and conjugates
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
EP2230517A1
(en)
|
2005-01-07 |
2010-09-22 |
Diadexus, Inc. |
OVR110 antibody compositions and methods of use
|
|
US20090226367A1
(en)
*
|
2005-03-11 |
2009-09-10 |
Euro-Celtique S.A. |
Compositions comprising an anti-ca125 antibody and a cytotoxic compound and their use for the treatment of cancer
|
|
US8759490B2
(en)
|
2005-03-24 |
2014-06-24 |
Millennium Pharamaceuticals, Inc. |
Antibodies that bind OV064 and methods of use therefor
|
|
US8323645B2
(en)
*
|
2005-03-24 |
2012-12-04 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind OV064 and methods of use therefor
|
|
JP3943118B2
(ja)
*
|
2005-04-28 |
2007-07-11 |
Sbシステム株式会社 |
電子情報保存方法及び装置、電子情報分割保存方法及び装置、電子情報分割復元処理方法及び装置並びにそれらのプログラム
|
|
WO2007067991A2
(en)
|
2005-12-08 |
2007-06-14 |
Medarex, Inc. |
Human monoclonal antibodies to o8e
|
|
US20070264407A1
(en)
*
|
2006-05-15 |
2007-11-15 |
Pepsico, Inc. |
Stabilizer for dairy products
|
|
US7989173B2
(en)
|
2006-12-27 |
2011-08-02 |
The Johns Hopkins University |
Detection and diagnosis of inflammatory disorders
|
|
EP2124998B8
(en)
*
|
2006-12-27 |
2015-05-06 |
The Johns Hopkins University |
Methods for detecting inflammation and auto-immune diseases
|
|
US20090142342A1
(en)
*
|
2006-12-27 |
2009-06-04 |
Johns Hopkins University |
B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
|
|
AU2009288730B2
(en)
|
2008-08-25 |
2013-06-20 |
Amplimmune, Inc. |
Compositions of PD-1 antagonists and methods of use
|
|
JP2012500855A
(ja)
*
|
2008-08-25 |
2012-01-12 |
アンプリミューン、インコーポレーテッド |
Pd−1アンタゴニストおよび感染性疾患を処置するための方法
|
|
CA2772204A1
(en)
|
2009-08-31 |
2011-03-03 |
Amplimmune, Inc. |
Methods and compositions for the inhibition of transplant rejection
|
|
JP2013504585A
(ja)
|
2009-09-09 |
2013-02-07 |
セントローズ, エルエルシー |
細胞外標的化薬物複合体
|
|
SI2528625T1
(sl)
|
2010-04-15 |
2013-11-29 |
Spirogen Sarl |
Pirolobenzodiazepini in njihovi konjugati
|
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
US20120121615A1
(en)
|
2010-11-17 |
2012-05-17 |
Flygare John A |
Alaninyl maytansinol antibody conjugates
|
|
US8679767B2
(en)
|
2011-05-12 |
2014-03-25 |
Genentech, Inc. |
Multiple reaction monitoring LC-MS/MS method to detect therapeutic antibodies in animal samples using framework signature peptides
|
|
BR112014009050B1
(pt)
|
2011-10-14 |
2022-06-21 |
Medimmune Limited |
Conjugado anticorpo-fármaco de pirrolbenzodiazepinas, composição farmacêutica que compreende o mesmo, bem como compostos de pirrolbenzodiazepinas
|
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
|
CA2873155C
(en)
*
|
2012-09-11 |
2022-07-26 |
Oncotherapy Science, Inc. |
Ube2t peptides and vaccines containing the same
|
|
EP2906297B1
(en)
|
2012-10-12 |
2017-12-06 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP2906296B1
(en)
|
2012-10-12 |
2018-03-21 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
|
RS57694B1
(sr)
|
2012-10-12 |
2018-11-30 |
Adc Therapeutics Sa |
Pirolobenzodiazepin - anti-psma konjugati antitela
|
|
HRP20182129T1
(hr)
|
2012-10-12 |
2019-02-08 |
Adc Therapeutics Sa |
Konjugati protutijelo - pirolobenzodiazepin
|
|
MX338711B
(es)
|
2012-10-12 |
2016-04-28 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas.
|
|
ES2680153T3
(es)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas
|
|
JP6392765B2
(ja)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
ピロロベンゾジアゼピン−抗体結合体
|
|
CN110627797A
(zh)
|
2012-12-21 |
2019-12-31 |
麦迪穆有限责任公司 |
用于治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物
|
|
CN105189507A
(zh)
|
2012-12-21 |
2015-12-23 |
斯皮罗根有限公司 |
吡咯并苯并二氮杂卓及其结合物
|
|
MX362970B
(es)
|
2013-03-13 |
2019-02-28 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas.
|
|
AU2014229529B2
(en)
|
2013-03-13 |
2018-02-15 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
TWI680766B
(zh)
|
2013-03-13 |
2020-01-01 |
英商梅迪繆思有限公司 |
吡咯并苯并二氮呯及其共軛物
|
|
BR112016002829A2
(pt)
|
2013-08-12 |
2017-09-19 |
Genentech Inc |
Composto e processo para preparar o composto de conjugado anticorpo-¿droga, composição farmacêutica, método de tratamento do câncer, kit para o tratamento do câncer, intermediário ligante¿-droga, porção e composto de porção droga de dímero cbi
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2015052534A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
JP6671292B2
(ja)
|
2013-12-16 |
2020-03-25 |
ジェネンテック, インコーポレイテッド |
ペプチド模倣化合物及びその抗体−薬物コンジュゲート
|
|
EP3082876B1
(en)
|
2013-12-16 |
2018-01-17 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
WO2015095227A2
(en)
|
2013-12-16 |
2015-06-25 |
Genentech, Inc. |
Peptidomimetic compounds and antibody-drug conjugates thereof
|
|
EP3193940A1
(en)
|
2014-09-10 |
2017-07-26 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2016040825A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anthracycline disulfide intermediates, antibody-drug conjugates and methods
|
|
SG11201701128YA
(en)
|
2014-09-12 |
2017-03-30 |
Genentech Inc |
Cysteine engineered antibodies and conjugates
|
|
CN107073136A
(zh)
|
2014-09-17 |
2017-08-18 |
健泰科生物技术公司 |
吡咯并苯并二氮杂卓及其抗体二硫化物偶联物
|
|
CN107148285B
(zh)
|
2014-11-25 |
2022-01-04 |
Adc治疗股份有限公司 |
吡咯并苯并二氮杂䓬-抗体缀合物
|
|
AU2015358532C1
(en)
|
2014-12-03 |
2020-10-29 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
|
AU2016243126A1
(en)
*
|
2015-03-27 |
2017-11-02 |
University Of Southern California |
CAR T-cells for the treatment of B7-H4 expressing solid tumors
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
CR20180243A
(es)
|
2015-10-02 |
2018-07-31 |
Genentech Inc |
Conjugados de anticuerpo-fármaco de pirrolobenzodiazepina y métodos de uso
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
EP3365025B1
(en)
|
2015-10-20 |
2020-07-15 |
Genentech, Inc. |
Calicheamicin-antibody-drug conjugates and methods of use
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
CN108700598A
(zh)
|
2016-03-25 |
2018-10-23 |
豪夫迈·罗氏有限公司 |
多路总抗体和抗体缀合的药物量化测定法
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
CN118436801A
(zh)
|
2016-05-20 |
2024-08-06 |
豪夫迈·罗氏有限公司 |
Protac抗体缀合物及其使用方法
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
WO2017214024A1
(en)
|
2016-06-06 |
2017-12-14 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
|
CN109689111B
(zh)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
吡咯并苯并二氮杂䓬前药及其抗体缀合物
|
|
JP7050770B2
(ja)
|
2016-10-05 |
2022-04-08 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗体薬物コンジュゲートの調製方法
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
RS61795B1
(sr)
|
2017-02-08 |
2021-06-30 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin antitela
|
|
CN110582505B
(zh)
|
2017-04-18 |
2021-04-02 |
免疫医疗有限公司 |
吡咯并苯并二氮杂*缀合物
|
|
WO2018193102A1
(en)
|
2017-04-20 |
2018-10-25 |
Adc Therapeutics Sa |
Combination therapy with an anti-axl antibody-drug conjugate
|
|
CA3064804A1
(en)
|
2017-06-14 |
2018-12-20 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-cd19 adc
|
|
KR102270107B1
(ko)
|
2017-08-18 |
2021-06-30 |
메디뮨 리미티드 |
피롤로벤조디아제핀 컨쥬게이트
|
|
US11306144B2
(en)
|
2017-08-25 |
2022-04-19 |
Five Prime Therapeutics, Inc. |
B7-H4 antibodies and methods of use thereof
|
|
EP3684773B1
(en)
|
2017-09-20 |
2026-04-29 |
pH Pharma Co., Ltd. |
Thailanstatin analogs
|
|
BR112020016986A2
(pt)
|
2018-02-21 |
2021-03-02 |
Five Prime Therapeutics, Inc. |
formulações de anticorpo contra b7-h4
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
KR20200144094A
(ko)
|
2018-03-02 |
2020-12-28 |
파이브 프라임 테라퓨틱스, 인크. |
B7-h4 항체 및 이의 사용 방법
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
JP7708662B2
(ja)
|
2018-10-24 |
2025-07-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
コンジュゲート化された化学的分解誘導物質および使用方法
|
|
JP2022513198A
(ja)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
CN113631560B
(zh)
|
2019-03-15 |
2025-02-18 |
麦迪穆有限责任公司 |
氮杂环丁烷并苯并二氮杂䓬二聚体和用于治疗癌症的包含它们的缀合物
|
|
TW202144388A
(zh)
*
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
EP4426727A2
(en)
|
2021-11-03 |
2024-09-11 |
Hangzhou Dac Biotech Co., Ltd. |
Specific conjugation of an antibody
|
|
WO2024138128A2
(en)
|
2022-12-23 |
2024-06-27 |
Genentech, Inc. |
Cereblon degrader conjugates, and uses thereof
|
|
KR20260012304A
(ko)
|
2023-04-17 |
2026-01-26 |
피크 바이오, 인크. |
항체 및 항체-약물 접합체 및 사용 방법 및 합성 공정 및 중간체
|
|
WO2026006689A2
(en)
|
2024-06-28 |
2026-01-02 |
Firefly Bio, Inc. |
Bcl-xl degrader antibody conjugates and uses thereof
|
|
WO2026006688A2
(en)
|
2024-06-28 |
2026-01-02 |
Firefly Bio, Inc. |
Degrader antibody conjugates and uses thereof
|