AU2022257039B2 - Thienopyrrole compounds - Google Patents
Thienopyrrole compoundsInfo
- Publication number
- AU2022257039B2 AU2022257039B2 AU2022257039A AU2022257039A AU2022257039B2 AU 2022257039 B2 AU2022257039 B2 AU 2022257039B2 AU 2022257039 A AU2022257039 A AU 2022257039A AU 2022257039 A AU2022257039 A AU 2022257039A AU 2022257039 B2 AU2022257039 B2 AU 2022257039B2
- Authority
- AU
- Australia
- Prior art keywords
- membered
- pharmaceutically acceptable
- acceptable salt
- heterocyclyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163176109P | 2021-04-16 | 2021-04-16 | |
| US63/176,109 | 2021-04-16 | ||
| US202163216418P | 2021-06-29 | 2021-06-29 | |
| US63/216,418 | 2021-06-29 | ||
| US202263305610P | 2022-02-01 | 2022-02-01 | |
| US63/305,610 | 2022-02-01 | ||
| PCT/US2022/024984 WO2022221642A1 (en) | 2021-04-16 | 2022-04-15 | Thienopyrrole compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2022257039A1 AU2022257039A1 (en) | 2023-10-05 |
| AU2022257039B2 true AU2022257039B2 (en) | 2026-06-18 |
Family
ID=81580723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022257039A Active AU2022257039B2 (en) | 2021-04-16 | 2022-04-15 | Thienopyrrole compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11661431B2 (enExample) |
| EP (1) | EP4323369A1 (enExample) |
| JP (1) | JP2024513945A (enExample) |
| KR (1) | KR20230171469A (enExample) |
| AU (1) | AU2022257039B2 (enExample) |
| BR (1) | BR112023021107A2 (enExample) |
| CA (1) | CA3214808A1 (enExample) |
| CL (2) | CL2023002998A1 (enExample) |
| CO (1) | CO2023013397A2 (enExample) |
| CR (1) | CR20230478A (enExample) |
| DO (1) | DOP2023000219A (enExample) |
| IL (1) | IL307203A (enExample) |
| MX (1) | MX2023012110A (enExample) |
| PE (1) | PE20240919A1 (enExample) |
| TW (2) | TWI908382B (enExample) |
| WO (1) | WO2022221642A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202440078A (zh) | 2021-09-10 | 2024-10-16 | 美商基利科學股份有限公司 | 噻吩并吡咯化合物 |
| WO2023247670A1 (en) * | 2022-06-24 | 2023-12-28 | F. Hoffmann-La Roche Ag | New heterocyclic-carbonyl-cyclic compounds as magl inhibitors |
| EP4619005A2 (en) * | 2022-11-18 | 2025-09-24 | The United States Government As Represented By The Department Of Veterans Affairs | Methods for treating rheumatoid arthritis using a syndecan-1 inhibitor or a syntenin-1 inhibitor |
| WO2024182811A1 (en) * | 2023-03-02 | 2024-09-06 | University Of South Florida | Compositions and methods for treating uterine leiomyomas |
| WO2025024265A1 (en) | 2023-07-21 | 2025-01-30 | Bristol-Myers Squibb Company | Methods of assessing citrullination and activity of pad4 modulators |
| WO2026020127A2 (en) | 2024-07-19 | 2026-01-22 | Bristol-Myers Squibb Company | Methods of assessing citrullination and activity of pad2 modulators |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021067326A1 (en) * | 2019-10-01 | 2021-04-08 | Bristol-Myers Squibb Company | Substituted bicyclic heteroaryl compounds |
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| US5364620A (en) | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5001139A (en) | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
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| RU2385865C2 (ru) | 2005-08-15 | 2010-04-10 | Айрм Ллк | Соединения и композиции в качестве миметиков тро |
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-
2022
- 2022-04-15 US US17/721,636 patent/US11661431B2/en active Active
- 2022-04-15 IL IL307203A patent/IL307203A/en unknown
- 2022-04-15 EP EP22721581.1A patent/EP4323369A1/en active Pending
- 2022-04-15 KR KR1020237039381A patent/KR20230171469A/ko active Pending
- 2022-04-15 WO PCT/US2022/024984 patent/WO2022221642A1/en not_active Ceased
- 2022-04-15 CR CR20230478A patent/CR20230478A/es unknown
- 2022-04-15 JP JP2023562311A patent/JP2024513945A/ja active Pending
- 2022-04-15 TW TW113138376A patent/TWI908382B/zh active
- 2022-04-15 TW TW111114449A patent/TWI861488B/zh active
- 2022-04-15 MX MX2023012110A patent/MX2023012110A/es unknown
- 2022-04-15 PE PE2023002819A patent/PE20240919A1/es unknown
- 2022-04-15 BR BR112023021107A patent/BR112023021107A2/pt unknown
- 2022-04-15 CA CA3214808A patent/CA3214808A1/en active Pending
- 2022-04-15 AU AU2022257039A patent/AU2022257039B2/en active Active
-
2023
- 2023-03-08 US US18/180,438 patent/US20230365594A1/en not_active Abandoned
- 2023-10-06 CL CL2023002998A patent/CL2023002998A1/es unknown
- 2023-10-09 DO DO2023000219A patent/DOP2023000219A/es unknown
- 2023-10-09 CO CONC2023/0013397A patent/CO2023013397A2/es unknown
-
2024
- 2024-04-24 CL CL2024001266A patent/CL2024001266A1/es unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021067326A1 (en) * | 2019-10-01 | 2021-04-08 | Bristol-Myers Squibb Company | Substituted bicyclic heteroaryl compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| PE20240919A1 (es) | 2024-04-30 |
| TW202519532A (zh) | 2025-05-16 |
| WO2022221642A1 (en) | 2022-10-20 |
| CA3214808A1 (en) | 2022-10-20 |
| TWI861488B (zh) | 2024-11-11 |
| CL2024001266A1 (es) | 2024-11-08 |
| CL2023002998A1 (es) | 2024-04-26 |
| BR112023021107A2 (pt) | 2023-12-12 |
| IL307203A (en) | 2023-11-01 |
| AU2022257039A1 (en) | 2023-10-05 |
| CR20230478A (es) | 2023-11-30 |
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