AU2020282707B2 - Tricyclic compounds - Google Patents
Tricyclic compounds Download PDFInfo
- Publication number
- AU2020282707B2 AU2020282707B2 AU2020282707A AU2020282707A AU2020282707B2 AU 2020282707 B2 AU2020282707 B2 AU 2020282707B2 AU 2020282707 A AU2020282707 A AU 2020282707A AU 2020282707 A AU2020282707 A AU 2020282707A AU 2020282707 B2 AU2020282707 B2 AU 2020282707B2
- Authority
- AU
- Australia
- Prior art keywords
- optionally substituted
- alkyl
- unsubstituted
- compound
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962854597P | 2019-05-30 | 2019-05-30 | |
| US62/854,597 | 2019-05-30 | ||
| PCT/US2020/034746 WO2020243199A1 (en) | 2019-05-30 | 2020-05-27 | Tricyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2020282707A1 AU2020282707A1 (en) | 2021-12-02 |
| AU2020282707B2 true AU2020282707B2 (en) | 2025-06-19 |
Family
ID=73552666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020282707A Expired - Fee Related AU2020282707B2 (en) | 2019-05-30 | 2020-05-27 | Tricyclic compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11136321B2 (enExample) |
| EP (1) | EP3976618A4 (enExample) |
| JP (1) | JP2022534501A (enExample) |
| KR (1) | KR20220016177A (enExample) |
| CN (1) | CN113906029A (enExample) |
| AU (1) | AU2020282707B2 (enExample) |
| BR (1) | BR112021023967A2 (enExample) |
| CA (1) | CA3138938A1 (enExample) |
| CL (1) | CL2021003139A1 (enExample) |
| CO (1) | CO2021017202A2 (enExample) |
| EA (1) | EA202192760A1 (enExample) |
| IL (1) | IL287813A (enExample) |
| MA (1) | MA56058A (enExample) |
| MX (1) | MX2021014458A (enExample) |
| PE (1) | PE20220427A1 (enExample) |
| PH (1) | PH12021552953A1 (enExample) |
| SG (1) | SG11202113214QA (enExample) |
| TW (1) | TW202110845A (enExample) |
| WO (1) | WO2020243199A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220000874A1 (en) * | 2019-05-30 | 2022-01-06 | Aligos Therapeutics, Inc. | Tricyclic compounds |
| CN114222746B (zh) * | 2019-12-10 | 2024-08-02 | 上海翰森生物医药科技有限公司 | 含吡唑多环类衍生物抑制剂、其制备方法和应用 |
| GB202103704D0 (en) * | 2021-03-17 | 2021-04-28 | Pathios Therapeutics Ltd | Compounds |
| EP4251625A4 (en) * | 2020-11-24 | 2024-10-09 | Aligos Therapeutics, Inc. | Tricyclic compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0701273D0 (en) | 2007-01-24 | 2007-02-28 | Angeletti P Ist Richerche Bio | New compounds |
| WO2008157273A1 (en) | 2007-06-14 | 2008-12-24 | Smithkline Beecham Corporation | Chemical compounds |
| WO2015065338A1 (en) | 2013-10-29 | 2015-05-07 | Medivir Ab | Quinazoline based respiratory syncytial virus inhibitors |
| AU2017231817B2 (en) | 2016-03-09 | 2021-02-25 | Emory University | Elimination of hepatitis B virus with antiviral agents |
| CN110066278B (zh) * | 2017-06-01 | 2021-06-08 | 广东东阳光药业有限公司 | 稠合三环类化合物及其在药物中的应用 |
-
2020
- 2020-05-27 AU AU2020282707A patent/AU2020282707B2/en not_active Expired - Fee Related
- 2020-05-27 JP JP2021570378A patent/JP2022534501A/ja active Pending
- 2020-05-27 CA CA3138938A patent/CA3138938A1/en active Pending
- 2020-05-27 CN CN202080040114.2A patent/CN113906029A/zh active Pending
- 2020-05-27 SG SG11202113214QA patent/SG11202113214QA/en unknown
- 2020-05-27 MX MX2021014458A patent/MX2021014458A/es unknown
- 2020-05-27 PH PH1/2021/552953A patent/PH12021552953A1/en unknown
- 2020-05-27 MA MA056058A patent/MA56058A/fr unknown
- 2020-05-27 PE PE2021001952A patent/PE20220427A1/es unknown
- 2020-05-27 US US16/885,128 patent/US11136321B2/en active Active
- 2020-05-27 KR KR1020217042967A patent/KR20220016177A/ko not_active Ceased
- 2020-05-27 WO PCT/US2020/034746 patent/WO2020243199A1/en not_active Ceased
- 2020-05-27 EA EA202192760A patent/EA202192760A1/ru unknown
- 2020-05-27 BR BR112021023967A patent/BR112021023967A2/pt not_active IP Right Cessation
- 2020-05-27 EP EP20812759.7A patent/EP3976618A4/en not_active Withdrawn
- 2020-05-29 TW TW109118090A patent/TW202110845A/zh unknown
-
2021
- 2021-11-03 IL IL287813A patent/IL287813A/en unknown
- 2021-11-25 CL CL2021003139A patent/CL2021003139A1/es unknown
- 2021-12-15 CO CONC2021/0017202A patent/CO2021017202A2/es unknown
Non-Patent Citations (1)
| Title |
|---|
| FANG, Z. ET AL.: "Discovery of pyrazolo [1, 5-a] pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 27, no. 14, 2017, pages 3201 - 3204. * |
Also Published As
| Publication number | Publication date |
|---|---|
| TW202110845A (zh) | 2021-03-16 |
| WO2020243199A1 (en) | 2020-12-03 |
| US11136321B2 (en) | 2021-10-05 |
| IL287813A (en) | 2022-01-01 |
| KR20220016177A (ko) | 2022-02-08 |
| MA56058A (fr) | 2022-04-06 |
| BR112021023967A2 (pt) | 2022-03-08 |
| PH12021552953A1 (en) | 2022-07-25 |
| SG11202113214QA (en) | 2021-12-30 |
| AU2020282707A1 (en) | 2021-12-02 |
| EA202192760A1 (ru) | 2022-03-05 |
| CL2021003139A1 (es) | 2022-09-23 |
| CO2021017202A2 (es) | 2022-01-17 |
| CA3138938A1 (en) | 2020-12-03 |
| JP2022534501A (ja) | 2022-08-01 |
| EP3976618A4 (en) | 2023-01-04 |
| CN113906029A (zh) | 2022-01-07 |
| MX2021014458A (es) | 2022-01-06 |
| EP3976618A1 (en) | 2022-04-06 |
| PE20220427A1 (es) | 2022-03-29 |
| US20200407361A1 (en) | 2020-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102085121B1 (ko) | 이미다조[1,2-b]피리다진계 화합물, 그를 포함하는 조성물 및 그의 용도 | |
| JP5978317B2 (ja) | 新規なインドリジン化合物、それらの調製方法及びそれらを含有する医薬組成物 | |
| JP7203816B2 (ja) | １，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン類似体 | |
| AU2004290643B2 (en) | 5,7-diaminopyrazolo [4,3-d] pyrimidines with PDE-5 inhibiting activity | |
| JP5642777B2 (ja) | Ｉａｐ阻害剤 | |
| CN105579450B (zh) | 新的吲嗪化合物、其制备方法和包含它们的药物组合物 | |
| JP6395829B2 (ja) | 新規イソインドリン又はイソキノリン化合物、それらの調製のためのプロセス及びそれらを含有する医薬組成物 | |
| ES2349476T3 (es) | Nuevos derivados de 4-ciano, 4-amino y 4-aminometilo de compuestos de pirazolo[1,5-a]piridinas, pirazolo[1,5-c]pirimidinas y 2h-indazol y derivados de 5-ciano, 5-amino y 5-aminometilo de compuestos de imidazo[1,2-a]piridinas e imidazo[1,5-a]pirazinas, como inhibidores de cinasa dependiente de ciclina. | |
| WO2015077193A1 (en) | Inhibitors of lysine methyl transferase | |
| JP2020524148A (ja) | 置換５−シアノインドール化合物及びその使用 | |
| PT2252611E (pt) | (di-hidro)pirrolo[2,1-a]isoquinolinas | |
| CA3197470A1 (en) | Bicyclic compounds | |
| JP2022534501A (ja) | 三環式化合物 | |
| WO2023178035A1 (en) | Multicyclic compounds | |
| ES2208404T3 (es) | Derivados de imidazo-triazina como ligandos de los receptores de3 gaba. | |
| KR20220002971A (ko) | 바이사이클릭 및 트라이사이클릭 화합물 | |
| CA3201456A1 (en) | Tricyclic compounds | |
| CN116262750A (zh) | 一种芳杂环类化合物及其制备方法和用途 | |
| JP2012528168A (ja) | Ｉａｐ阻害剤 | |
| JP2009513640A (ja) | Ｈｉｖインテグラーゼインヒビター | |
| TW509692B (en) | 2-amino-7-(1-substituted-2-hydroxyethyl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-ones | |
| US20220000874A1 (en) | Tricyclic compounds | |
| CN115894376B (zh) | 一种芳香族酰胺类化合物、药物组合物及其用途 | |
| WO2025255442A1 (en) | Trim21-targeted compounds and uses thereof | |
| TW202547470A (zh) | 作為KCa3.1鉀通道阻斷劑之氮雜吲哚啉酮化合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK25 | Application lapsed reg. 22.2i(2) - failure to pay acceptance fee |