PH12021552953A1 - Tricyclic compounds - Google Patents

Tricyclic compounds

Info

Publication number
PH12021552953A1
PH12021552953A1 PH1/2021/552953A PH12021552953A PH12021552953A1 PH 12021552953 A1 PH12021552953 A1 PH 12021552953A1 PH 12021552953 A PH12021552953 A PH 12021552953A PH 12021552953 A1 PH12021552953 A1 PH 12021552953A1
Authority
PH
Philippines
Prior art keywords
pharmaceutically acceptable
tricyclic compounds
formula
methods
acceptable salts
Prior art date
Application number
PH1/2021/552953A
Other languages
English (en)
Inventor
Sandrine Vendeville
Original Assignee
Aligos Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aligos Therapeutics Inc filed Critical Aligos Therapeutics Inc
Publication of PH12021552953A1 publication Critical patent/PH12021552953A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH1/2021/552953A 2019-05-30 2020-05-27 Tricyclic compounds PH12021552953A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962854597P 2019-05-30 2019-05-30
PCT/US2020/034746 WO2020243199A1 (en) 2019-05-30 2020-05-27 Tricyclic compounds

Publications (1)

Publication Number Publication Date
PH12021552953A1 true PH12021552953A1 (en) 2022-07-25

Family

ID=73552666

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2021/552953A PH12021552953A1 (en) 2019-05-30 2020-05-27 Tricyclic compounds

Country Status (19)

Country Link
US (1) US11136321B2 (enExample)
EP (1) EP3976618A4 (enExample)
JP (1) JP2022534501A (enExample)
KR (1) KR20220016177A (enExample)
CN (1) CN113906029A (enExample)
AU (1) AU2020282707B2 (enExample)
BR (1) BR112021023967A2 (enExample)
CA (1) CA3138938A1 (enExample)
CL (1) CL2021003139A1 (enExample)
CO (1) CO2021017202A2 (enExample)
EA (1) EA202192760A1 (enExample)
IL (1) IL287813A (enExample)
MA (1) MA56058A (enExample)
MX (1) MX2021014458A (enExample)
PE (1) PE20220427A1 (enExample)
PH (1) PH12021552953A1 (enExample)
SG (1) SG11202113214QA (enExample)
TW (1) TW202110845A (enExample)
WO (1) WO2020243199A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220000874A1 (en) * 2019-05-30 2022-01-06 Aligos Therapeutics, Inc. Tricyclic compounds
CN114222746B (zh) * 2019-12-10 2024-08-02 上海翰森生物医药科技有限公司 含吡唑多环类衍生物抑制剂、其制备方法和应用
GB202103704D0 (en) * 2021-03-17 2021-04-28 Pathios Therapeutics Ltd Compounds
EP4251625A4 (en) * 2020-11-24 2024-10-09 Aligos Therapeutics, Inc. Tricyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0701273D0 (en) 2007-01-24 2007-02-28 Angeletti P Ist Richerche Bio New compounds
WO2008157273A1 (en) 2007-06-14 2008-12-24 Smithkline Beecham Corporation Chemical compounds
WO2015065338A1 (en) 2013-10-29 2015-05-07 Medivir Ab Quinazoline based respiratory syncytial virus inhibitors
AU2017231817B2 (en) 2016-03-09 2021-02-25 Emory University Elimination of hepatitis B virus with antiviral agents
CN110066278B (zh) * 2017-06-01 2021-06-08 广东东阳光药业有限公司 稠合三环类化合物及其在药物中的应用

Also Published As

Publication number Publication date
TW202110845A (zh) 2021-03-16
WO2020243199A1 (en) 2020-12-03
US11136321B2 (en) 2021-10-05
IL287813A (en) 2022-01-01
KR20220016177A (ko) 2022-02-08
MA56058A (fr) 2022-04-06
BR112021023967A2 (pt) 2022-03-08
SG11202113214QA (en) 2021-12-30
AU2020282707A1 (en) 2021-12-02
EA202192760A1 (ru) 2022-03-05
AU2020282707B2 (en) 2025-06-19
CL2021003139A1 (es) 2022-09-23
CO2021017202A2 (es) 2022-01-17
CA3138938A1 (en) 2020-12-03
JP2022534501A (ja) 2022-08-01
EP3976618A4 (en) 2023-01-04
CN113906029A (zh) 2022-01-07
MX2021014458A (es) 2022-01-06
EP3976618A1 (en) 2022-04-06
PE20220427A1 (es) 2022-03-29
US20200407361A1 (en) 2020-12-31

Similar Documents

Publication Publication Date Title
MX2024000299A (es) Compuestos antivirales.
PH12021552482A1 (en) Compounds targeting prmt5
ZA202206923B (en) New methylquinazolinone derivatives
PH12021552513A1 (en) Pyrrole compounds
MX2022004451A (es) Heteroaril-bifenil-amidas para el tratamiento de enfermedades relacionadas con el ligando pd-l1.
AU2019231551A8 (en) Substituted 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-ones
ZA202100485B (en) Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same
PH12021550825A1 (en) Quinoline derivatives as alpha4beta7 integrin inhibitors
EP4356975A3 (en) Erbb/btk inhibitors
MX2022004450A (es) Aminas de heteroaril-bifenilo para el tratamiento de enfermedades pd-l1.
MX2021007247A (es) Derivados de rapamicina.
MX2020013297A (es) Compuestos para el tratamiento o la prevencion de enfermedades hepaticas.
EA202192760A1 (ru) Трициклические соединения
CR20210181A (es) Inhibidores de o-glicoproteína-2-acetamido-2-desoxi-3-d-glucopiranosidasa
ZA202204442B (en) Salt forms of a complement component c5a receptor
PH12021550452A1 (en) Methods of treating mycobacterial infections using tetracycline compounds
PH12020552186A1 (en) Cyanotriazole compounds and uses thereof
MX2021009717A (es) Sulfonamidas biciclicas.
SG11201907945YA (en) Azetidine derivative
PH12019502046A1 (en) Pyrrolotriazine derivatives as kinase inhibitor
AU2019296118A8 (en) Isothiazolo(5,4-d)pyrimidine compound as IRAK4 inhibitor
WO2020251871A3 (en) Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
ZA202400679B (en) Dimethyl-substituted thiazololactam compound and use thereof
MA67325B1 (fr) Dérivés de naphtyridinone pour le traitement d'une maladie ou d'un trouble
PH12021550323A1 (en) Dendrimer formulations