AU2019364542B2 - Polymorphic compounds and uses thereof - Google Patents

Polymorphic compounds and uses thereof

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Publication number
AU2019364542B2
AU2019364542B2 AU2019364542A AU2019364542A AU2019364542B2 AU 2019364542 B2 AU2019364542 B2 AU 2019364542B2 AU 2019364542 A AU2019364542 A AU 2019364542A AU 2019364542 A AU2019364542 A AU 2019364542A AU 2019364542 B2 AU2019364542 B2 AU 2019364542B2
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AU
Australia
Prior art keywords
compound
compound according
xrpd
patient
present
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Active
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AU2019364542A
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English (en)
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AU2019364542A1 (en
Inventor
Silvia LENZINI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Navitor Pharmaceuticals Inc
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Navitor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Navitor Pharmaceuticals Inc filed Critical Navitor Pharmaceuticals Inc
Publication of AU2019364542A1 publication Critical patent/AU2019364542A1/en
Application granted granted Critical
Publication of AU2019364542B2 publication Critical patent/AU2019364542B2/en
Priority to AU2025271494A priority Critical patent/AU2025271494A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/04—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • C07C225/06—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
AU2019364542A 2018-10-24 2019-10-24 Polymorphic compounds and uses thereof Active AU2019364542B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025271494A AU2025271494A1 (en) 2018-10-24 2025-11-28 Polymorphic compounds and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862749922P 2018-10-24 2018-10-24
US62/749,922 2018-10-24
PCT/US2019/057815 WO2020086816A1 (en) 2018-10-24 2019-10-24 Polymorphic compounds and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025271494A Division AU2025271494A1 (en) 2018-10-24 2025-11-28 Polymorphic compounds and uses thereof

Publications (2)

Publication Number Publication Date
AU2019364542A1 AU2019364542A1 (en) 2021-06-10
AU2019364542B2 true AU2019364542B2 (en) 2025-08-28

Family

ID=70328246

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2019364542A Active AU2019364542B2 (en) 2018-10-24 2019-10-24 Polymorphic compounds and uses thereof
AU2025271494A Pending AU2025271494A1 (en) 2018-10-24 2025-11-28 Polymorphic compounds and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025271494A Pending AU2025271494A1 (en) 2018-10-24 2025-11-28 Polymorphic compounds and uses thereof

Country Status (8)

Country Link
US (4) US11345654B2 (https=)
EP (1) EP3870158A4 (https=)
JP (2) JP7644002B2 (https=)
CN (1) CN113164414A (https=)
AU (2) AU2019364542B2 (https=)
CA (1) CA3117336A1 (https=)
MX (2) MX2021004710A (https=)
WO (1) WO2020086816A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016342027B2 (en) 2015-10-23 2021-05-13 Navitor Pharmaceuticals, Inc. Modulators of Sestrin-GATOR2 interaction and uses thereof
PL3615019T3 (pl) 2017-04-26 2026-01-19 Navitor Pharmaceuticals, Inc. Modulator interakcji sestryna-gator2 do zastosowania w leczeniu depresji opornej na leczenie
EP3870158A4 (en) 2018-10-24 2022-08-10 Navitor Pharmaceuticals, Inc. Polymorphic compounds and uses thereof
US11723890B2 (en) 2019-11-01 2023-08-15 Navitor Pharmaceuticals, Inc. Methods of treatment using an mTORC1 modulator
CN115927459A (zh) * 2022-07-19 2023-04-07 华南农业大学 猪ctns基因在促进动物骨骼肌生长中的应用
AU2023374029A1 (en) * 2022-11-01 2025-05-08 Navitor Pharmaceuticals, Inc. MODULATORS OF mTORC1 ACTIVITY AND USES THEREOF

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170114080A1 (en) * 2015-10-23 2017-04-27 Navitor Pharmaceuticals, Inc. Modulators of sestrin-gator2 interaction and uses thereof

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Also Published As

Publication number Publication date
US11697633B2 (en) 2023-07-11
MX2025010903A (es) 2025-10-01
US11345654B2 (en) 2022-05-31
JP2022505849A (ja) 2022-01-14
US20250188017A1 (en) 2025-06-12
WO2020086816A1 (en) 2020-04-30
JP7644002B2 (ja) 2025-03-11
AU2019364542A1 (en) 2021-06-10
MX2021004710A (es) 2021-06-04
EP3870158A4 (en) 2022-08-10
CN113164414A (zh) 2021-07-23
JP2025000975A (ja) 2025-01-07
CA3117336A1 (en) 2020-04-30
AU2025271494A1 (en) 2026-01-08
US20240018091A1 (en) 2024-01-18
EP3870158A1 (en) 2021-09-01
US20200131114A1 (en) 2020-04-30
US12252456B2 (en) 2025-03-18
US20220371985A1 (en) 2022-11-24

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