JP7644002B2 - 多形化合物およびその使用 - Google Patents

多形化合物およびその使用 Download PDF

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JP7644002B2
JP7644002B2 JP2021522528A JP2021522528A JP7644002B2 JP 7644002 B2 JP7644002 B2 JP 7644002B2 JP 2021522528 A JP2021522528 A JP 2021522528A JP 2021522528 A JP2021522528 A JP 2021522528A JP 7644002 B2 JP7644002 B2 JP 7644002B2
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JP2022505849A (ja
JP2022505849A5 (https=
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シルヴィア レンツィーニ，
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ナビター ファーマシューティカルズ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/04—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • C07C225/06—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
JP2021522528A 2018-10-24 2019-10-24 多形化合物およびその使用 Active JP7644002B2 (ja)

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JP2024174435A JP2025000975A (ja) 2018-10-24 2024-10-03 多形化合物およびその使用

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US201862749922P 2018-10-24 2018-10-24
US62/749,922 2018-10-24
PCT/US2019/057815 WO2020086816A1 (en) 2018-10-24 2019-10-24 Polymorphic compounds and uses thereof

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JP2022505849A JP2022505849A (ja) 2022-01-14
JP2022505849A5 JP2022505849A5 (https=) 2022-10-31
JP7644002B2 true JP7644002B2 (ja) 2025-03-11

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EP (1) EP3870158A4 (https=)
JP (2) JP7644002B2 (https=)
CN (1) CN113164414A (https=)
AU (2) AU2019364542B2 (https=)
CA (1) CA3117336A1 (https=)
MX (2) MX2021004710A (https=)
WO (1) WO2020086816A1 (https=)

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AU2016342027B2 (en) 2015-10-23 2021-05-13 Navitor Pharmaceuticals, Inc. Modulators of Sestrin-GATOR2 interaction and uses thereof
PL3615019T3 (pl) 2017-04-26 2026-01-19 Navitor Pharmaceuticals, Inc. Modulator interakcji sestryna-gator2 do zastosowania w leczeniu depresji opornej na leczenie
EP3870158A4 (en) 2018-10-24 2022-08-10 Navitor Pharmaceuticals, Inc. Polymorphic compounds and uses thereof
US11723890B2 (en) 2019-11-01 2023-08-15 Navitor Pharmaceuticals, Inc. Methods of treatment using an mTORC1 modulator
CN115927459A (zh) * 2022-07-19 2023-04-07 华南农业大学 猪ctns基因在促进动物骨骼肌生长中的应用
AU2023374029A1 (en) * 2022-11-01 2025-05-08 Navitor Pharmaceuticals, Inc. MODULATORS OF mTORC1 ACTIVITY AND USES THEREOF

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US11697633B2 (en) 2023-07-11
AU2019364542B2 (en) 2025-08-28
MX2025010903A (es) 2025-10-01
US11345654B2 (en) 2022-05-31
JP2022505849A (ja) 2022-01-14
US20250188017A1 (en) 2025-06-12
WO2020086816A1 (en) 2020-04-30
AU2019364542A1 (en) 2021-06-10
MX2021004710A (es) 2021-06-04
EP3870158A4 (en) 2022-08-10
CN113164414A (zh) 2021-07-23
JP2025000975A (ja) 2025-01-07
CA3117336A1 (en) 2020-04-30
AU2025271494A1 (en) 2026-01-08
US20240018091A1 (en) 2024-01-18
EP3870158A1 (en) 2021-09-01
US20200131114A1 (en) 2020-04-30
US12252456B2 (en) 2025-03-18
US20220371985A1 (en) 2022-11-24

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