AU2016381336A1 - Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists - Google Patents

Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists Download PDF

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Publication number
AU2016381336A1
AU2016381336A1 AU2016381336A AU2016381336A AU2016381336A1 AU 2016381336 A1 AU2016381336 A1 AU 2016381336A1 AU 2016381336 A AU2016381336 A AU 2016381336A AU 2016381336 A AU2016381336 A AU 2016381336A AU 2016381336 A1 AU2016381336 A1 AU 2016381336A1
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Prior art keywords
disease
compound
amino
disorder
pct
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AU2016381336A
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David W. Griggs
Peter G. Ruminski
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Saint Louis University
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Saint Louis University
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Diabetes (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
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  • Neurology (AREA)
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  • Ophthalmology & Optometry (AREA)
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AU2016381336A 2015-12-30 2016-12-30 Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists Abandoned AU2016381336A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562273246P 2015-12-30 2015-12-30
US62/273,246 2015-12-30
PCT/US2016/069511 WO2017117538A1 (en) 2015-12-30 2016-12-30 Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists

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AU2016381336A1 true AU2016381336A1 (en) 2018-06-28

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AU2016381336A Abandoned AU2016381336A1 (en) 2015-12-30 2016-12-30 Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists

Country Status (16)

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US (3) US10035778B2 (enExample)
EP (2) EP3738953A1 (enExample)
JP (1) JP2019500355A (enExample)
KR (1) KR20180107121A (enExample)
CN (1) CN108779077A (enExample)
AU (1) AU2016381336A1 (enExample)
BR (1) BR112018012981A2 (enExample)
CA (1) CA3008023A1 (enExample)
CO (1) CO2018007278A2 (enExample)
ES (1) ES2806276T3 (enExample)
HK (1) HK1244806A1 (enExample)
IL (1) IL259951A (enExample)
PH (1) PH12018501362A1 (enExample)
RU (1) RU2729518C2 (enExample)
SG (1) SG11201805387RA (enExample)
WO (1) WO2017117538A1 (enExample)

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WO2020047208A1 (en) 2018-08-29 2020-03-05 Morphic Therapeutic, Inc. Inhibitors of (alpha-v)(beta-6) integrin
AU2019327475B2 (en) 2018-08-29 2025-06-05 Morphic Therapeutic, Inc. INHIBITING αV β6 INTEGRIN
PT3844162T (pt) 2018-08-29 2025-03-28 Morphic Therapeutic Inc Inibidores da integrina alfa v beta6
EP4034236A1 (en) 2019-09-26 2022-08-03 Abionyx Pharma SA Compounds useful for treating liver diseases
EP4076454A1 (en) * 2019-12-20 2022-10-26 Novartis AG Combination treatment of liver diseases using integrin inhibitors
WO2021216378A1 (en) 2020-04-23 2021-10-28 The Schepens Eye Research Institute, Inc. Methods and materials for treatment of fibrosis
JP7661969B2 (ja) * 2020-05-14 2025-04-15 Ｕｂｅ株式会社 １，４，５，６－テトラヒドロピリミジン－２－アミン誘導体
WO2022189856A1 (en) 2021-03-08 2022-09-15 Abionyx Pharma Sa Compounds useful for treating liver diseases
JPWO2023085396A1 (enExample) 2021-11-12 2023-05-19
EP4733297A1 (en) * 2023-06-22 2026-04-29 Antibody Therapeutics, Inc. Integrin-inhibiting small molecule compound

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