AU2016268250B2 - Autotaxin inhibitors and uses thereof - Google Patents

Autotaxin inhibitors and uses thereof Download PDF

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Publication number
AU2016268250B2
AU2016268250B2 AU2016268250A AU2016268250A AU2016268250B2 AU 2016268250 B2 AU2016268250 B2 AU 2016268250B2 AU 2016268250 A AU2016268250 A AU 2016268250A AU 2016268250 A AU2016268250 A AU 2016268250A AU 2016268250 B2 AU2016268250 B2 AU 2016268250B2
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compound
autotaxin inhibitor
autotaxin
mammal
administration
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AU2016268250A
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AU2016268250A1 (en
Inventor
Gretchen Bain
Jillian Frances Evans
John Howard Hutchinson
David Lonergan
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Sabre Therapeutics LLC
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Sabre Therapeutics LLC
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Publication of AU2016268250A1 publication Critical patent/AU2016268250A1/en
Assigned to SABRE THERAPEUTICS LLC reassignment SABRE THERAPEUTICS LLC Request for Assignment Assignors: PHARMAKEA, INC.
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Publication of AU2016268250B2 publication Critical patent/AU2016268250B2/en
Priority to AU2020239656A priority Critical patent/AU2020239656B2/en
Priority to AU2022228098A priority patent/AU2022228098A1/en
Priority to AU2024264577A priority patent/AU2024264577A1/en
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C—CHEMISTRY; METALLURGY
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Chemical Kinetics & Catalysis (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Endocrinology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
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AU2016268250A 2015-05-27 2016-05-24 Autotaxin inhibitors and uses thereof Active AU2016268250B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2020239656A AU2020239656B2 (en) 2015-05-27 2020-09-22 Autotaxin inhibitors and uses thereof
AU2022228098A AU2022228098A1 (en) 2015-05-27 2022-09-06 Autotaxin inhibitors and uses thereof
AU2024264577A AU2024264577A1 (en) 2015-05-27 2024-11-12 Autotaxin inhibitors and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562167216P 2015-05-27 2015-05-27
US62/167,216 2015-05-27
PCT/US2016/033933 WO2016191427A1 (en) 2015-05-27 2016-05-24 Autotaxin inhibitors and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020239656A Division AU2020239656B2 (en) 2015-05-27 2020-09-22 Autotaxin inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
AU2016268250A1 AU2016268250A1 (en) 2017-12-14
AU2016268250B2 true AU2016268250B2 (en) 2020-08-27

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Family Applications (4)

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AU2016268250A Active AU2016268250B2 (en) 2015-05-27 2016-05-24 Autotaxin inhibitors and uses thereof
AU2020239656A Active AU2020239656B2 (en) 2015-05-27 2020-09-22 Autotaxin inhibitors and uses thereof
AU2022228098A Abandoned AU2022228098A1 (en) 2015-05-27 2022-09-06 Autotaxin inhibitors and uses thereof
AU2024264577A Pending AU2024264577A1 (en) 2015-05-27 2024-11-12 Autotaxin inhibitors and uses thereof

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AU2020239656A Active AU2020239656B2 (en) 2015-05-27 2020-09-22 Autotaxin inhibitors and uses thereof
AU2022228098A Abandoned AU2022228098A1 (en) 2015-05-27 2022-09-06 Autotaxin inhibitors and uses thereof
AU2024264577A Pending AU2024264577A1 (en) 2015-05-27 2024-11-12 Autotaxin inhibitors and uses thereof

Country Status (14)

Country Link
US (2) US10632104B2 (enExample)
EP (2) EP3302490B1 (enExample)
JP (2) JP6873919B2 (enExample)
KR (2) KR20240060887A (enExample)
CN (2) CN107921048A (enExample)
AU (4) AU2016268250B2 (enExample)
BR (1) BR122023011445B1 (enExample)
CA (1) CA2986759C (enExample)
EA (2) EA039684B1 (enExample)
ES (1) ES2915267T3 (enExample)
IL (2) IL280863B2 (enExample)
MX (2) MX2017015225A (enExample)
SG (1) SG10201911204WA (enExample)
WO (1) WO2016191427A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015077503A1 (en) 2013-11-22 2015-05-28 Pharmakea, Inc. Autotaxin inhibitor compounds
AU2016268250B2 (en) 2015-05-27 2020-08-27 Sabre Therapeutics Llc Autotaxin inhibitors and uses thereof
CN107021915A (zh) * 2017-04-27 2017-08-08 李亚庆 一种治疗妇科炎症的化合物及制备方法和应用
EP3668993A4 (en) * 2017-08-14 2021-05-12 Camp4 Therapeutics Corporation HEPATIC DISEASE TREATMENT METHODS
WO2019172651A1 (ko) 2018-03-06 2019-09-12 주식회사 엘지화학 편광판 및 이를 포함하는 화상 표시 장치
CN113056266A (zh) * 2018-09-18 2021-06-29 梅塔科林公司 用于治疗疾病的法尼醇x受体激动剂
CN117018202A (zh) * 2019-07-08 2023-11-10 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
IL313660A (en) 2021-12-22 2024-08-01 Camp4 Therapeutics Corp Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs
CN114767863B (zh) * 2022-04-29 2024-01-30 西北工业大学 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用
CA3251769A1 (en) * 2022-05-03 2023-11-09 Sabre Therapeutics Llc POLYMORPHIC AND SALINE FORMS OF THE AUTOTAXIN INHIBITOR CUDETAXESTAT
US20250281486A1 (en) * 2022-05-05 2025-09-11 The Trustees Of Indiana University Therapeutic strategies to manage facial contractures post injury
GR1010570B (el) 2022-12-22 2023-11-17 Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Α.Β.Ε.Ε., 4-(2-(4-((2,4-διοξοθειαζολιδιν-5-υλ)μεθυλ)φαινοξυ) παραγωγα με δραση αναστολης της αυτοταξινης
TW202502735A (zh) * 2023-03-02 2025-01-16 印度商吉德斯生命科學有限公司 新穎atx抑制劑
CN116239577A (zh) * 2023-03-27 2023-06-09 沈阳药科大学 一种制备Cudetaxestat的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012024620A2 (en) * 2010-08-20 2012-02-23 Amira Pharmaceuticals, Inc. Autotaxin inhibitors and uses thereof
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