SG10201911204WA - Autotaxin inhibitors and uses thereof - Google Patents
Autotaxin inhibitors and uses thereofInfo
- Publication number
- SG10201911204WA SG10201911204WA SG10201911204WA SG10201911204WA SG10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA
- Authority
- SG
- Singapore
- Prior art keywords
- autotaxin inhibitors
- autotaxin
- inhibitors
- Prior art date
Links
Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Nutrition Science (AREA)
- Reproductive Health (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562167216P | 2015-05-27 | 2015-05-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201911204WA true SG10201911204WA (en) | 2020-02-27 |
Family
ID=57393709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201911204WA SG10201911204WA (en) | 2015-05-27 | 2016-05-24 | Autotaxin inhibitors and uses thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10632104B2 (enExample) |
| EP (2) | EP4026549A1 (enExample) |
| JP (2) | JP6873919B2 (enExample) |
| KR (2) | KR20240060887A (enExample) |
| CN (2) | CN107921048A (enExample) |
| AU (4) | AU2016268250B2 (enExample) |
| BR (1) | BR122023011445B1 (enExample) |
| CA (1) | CA2986759C (enExample) |
| EA (2) | EA039684B1 (enExample) |
| ES (1) | ES2915267T3 (enExample) |
| IL (2) | IL280863B2 (enExample) |
| MX (2) | MX2017015225A (enExample) |
| SG (1) | SG10201911204WA (enExample) |
| WO (1) | WO2016191427A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2930737C (en) | 2013-11-22 | 2023-02-21 | Pharmakea, Inc. | Autotaxin inhibitor compounds |
| SG10201911204WA (en) | 2015-05-27 | 2020-02-27 | Pharmakea Inc | Autotaxin inhibitors and uses thereof |
| CN107021915A (zh) * | 2017-04-27 | 2017-08-08 | 李亚庆 | 一种治疗妇科炎症的化合物及制备方法和应用 |
| CN111094581A (zh) * | 2017-08-14 | 2020-05-01 | 4阵营疗法公司 | 治疗肝病的方法 |
| WO2019172651A1 (ko) | 2018-03-06 | 2019-09-12 | 주식회사 엘지화학 | 편광판 및 이를 포함하는 화상 표시 장치 |
| CA3112414A1 (en) * | 2018-09-18 | 2020-03-26 | Metacrine, Inc. | Farnesoid x receptor agonists for the treatment of disease |
| CN112190708B (zh) * | 2019-07-08 | 2023-09-05 | 上海交通大学医学院附属瑞金医院 | 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用 |
| IL313660A (en) | 2021-12-22 | 2024-08-01 | Camp4 Therapeutics Corp | Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs |
| CN114767863B (zh) * | 2022-04-29 | 2024-01-30 | 西北工业大学 | 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用 |
| CN120112527A (zh) * | 2022-05-03 | 2025-06-06 | 迪方知识产权收购有限责任公司 | 自分泌运动因子抑制剂cudetaxestat的多晶型形式和盐形式 |
| US20250281486A1 (en) * | 2022-05-05 | 2025-09-11 | The Trustees Of Indiana University | Therapeutic strategies to manage facial contractures post injury |
| GR1010570B (el) | 2022-12-22 | 2023-11-17 | Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Α.Β.Ε.Ε., | 4-(2-(4-((2,4-διοξοθειαζολιδιν-5-υλ)μεθυλ)φαινοξυ) παραγωγα με δραση αναστολης της αυτοταξινης |
| TW202502735A (zh) * | 2023-03-02 | 2025-01-16 | 印度商吉德斯生命科學有限公司 | 新穎atx抑制劑 |
| CN116239577A (zh) * | 2023-03-27 | 2023-06-09 | 沈阳药科大学 | 一种制备Cudetaxestat的方法 |
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| DE69316741T2 (de) | 1992-11-10 | 1998-09-10 | Caterpillar Inc | Magnetventil |
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| GB9514473D0 (en) | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
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| US6890933B1 (en) | 2000-02-24 | 2005-05-10 | President And Fellows Of Harvard College | Kinesin inhibitors |
| ATE332903T1 (de) | 2000-10-03 | 2006-08-15 | Lilly Icos Llc | Kondensierte pyridoindolderivate |
| CA2444501C (en) | 2001-04-11 | 2009-11-17 | Idenix (Cayman) Limited | Phenylindoles for the treatment of hiv |
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| US7528165B2 (en) | 2001-12-13 | 2009-05-05 | National Health Research Institutes | Indole compounds |
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| DK1537078T3 (da) | 2002-08-29 | 2010-08-02 | Merck Sharp & Dohme | Indoler med anti-diabetisk aktivitet |
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