ES2915267T3 - Inhibidores de autotaxina y usos de los mismos - Google Patents

Inhibidores de autotaxina y usos de los mismos Download PDF

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Publication number
ES2915267T3
ES2915267T3 ES16800640T ES16800640T ES2915267T3 ES 2915267 T3 ES2915267 T3 ES 2915267T3 ES 16800640 T ES16800640 T ES 16800640T ES 16800640 T ES16800640 T ES 16800640T ES 2915267 T3 ES2915267 T3 ES 2915267T3
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Spain
Prior art keywords
compound
autotaxin
disease
autotaxin inhibitor
condition
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Active
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ES16800640T
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English (en)
Spanish (es)
Inventor
Gretchen Bain
Jillian Frances Evans
John Howard Hutchinson
David Lonergan
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Sabre Therapeutics LLC
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Sabre Therapeutics LLC
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
ES16800640T 2015-05-27 2016-05-24 Inhibidores de autotaxina y usos de los mismos Active ES2915267T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562167216P 2015-05-27 2015-05-27
PCT/US2016/033933 WO2016191427A1 (en) 2015-05-27 2016-05-24 Autotaxin inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
ES2915267T3 true ES2915267T3 (es) 2022-06-21

Family

ID=57393709

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16800640T Active ES2915267T3 (es) 2015-05-27 2016-05-24 Inhibidores de autotaxina y usos de los mismos

Country Status (14)

Country Link
US (2) US10632104B2 (enExample)
EP (2) EP3302490B1 (enExample)
JP (2) JP6873919B2 (enExample)
KR (2) KR20240060887A (enExample)
CN (2) CN116059203A (enExample)
AU (4) AU2016268250B2 (enExample)
BR (1) BR122023011445B1 (enExample)
CA (1) CA2986759C (enExample)
EA (2) EA039684B1 (enExample)
ES (1) ES2915267T3 (enExample)
IL (2) IL280863B2 (enExample)
MX (2) MX2017015225A (enExample)
SG (1) SG10201911204WA (enExample)
WO (1) WO2016191427A1 (enExample)

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KR102367876B1 (ko) 2013-11-22 2022-02-24 사브레 테라퓨틱스 엘엘씨 오토탁신 억제제 화합물
JP6873919B2 (ja) 2015-05-27 2021-05-19 セイバー セラピューティクス エルエルシー オートタキシン阻害剤とその使用
CN107021915A (zh) * 2017-04-27 2017-08-08 李亚庆 一种治疗妇科炎症的化合物及制备方法和应用
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WO2019172651A1 (ko) 2018-03-06 2019-09-12 주식회사 엘지화학 편광판 및 이를 포함하는 화상 표시 장치
WO2020061114A1 (en) * 2018-09-18 2020-03-26 Metacrine, Inc. Farnesoid x receptor agonists for the treatment of disease
CN112190708B (zh) * 2019-07-08 2023-09-05 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
MX2024007790A (es) 2021-12-22 2024-09-06 Camp4 Therapeutics Corp Modulación de la transcripción génica utilizando oligonucleótidos antisentido dirigidos a arn reguladores.
CN114767863B (zh) * 2022-04-29 2024-01-30 西北工业大学 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用
CN120112527A (zh) * 2022-05-03 2025-06-06 迪方知识产权收购有限责任公司 自分泌运动因子抑制剂cudetaxestat的多晶型形式和盐形式
US20250281486A1 (en) * 2022-05-05 2025-09-11 The Trustees Of Indiana University Therapeutic strategies to manage facial contractures post injury
GR1010570B (el) 2022-12-22 2023-11-17 Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Α.Β.Ε.Ε., 4-(2-(4-((2,4-διοξοθειαζολιδιν-5-υλ)μεθυλ)φαινοξυ) παραγωγα με δραση αναστολης της αυτοταξινης
TW202502735A (zh) * 2023-03-02 2025-01-16 印度商吉德斯生命科學有限公司 新穎atx抑制劑
CN116239577A (zh) * 2023-03-27 2023-06-09 沈阳药科大学 一种制备Cudetaxestat的方法

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